HsaEX1018045 @ hg38
Exon Skipping
Gene
ENSG00000082781 | ITGB5
Description
integrin subunit beta 5 [Source:HGNC Symbol;Acc:HGNC:6160]
Coordinates
chr3:124769013-124773912:-
Coord C1 exon
chr3:124773690-124773912
Coord A exon
chr3:124772416-124772822
Coord C2 exon
chr3:124769013-124769111
Length
407 bp
Sequences
Splice sites
3' ss Seq
TTTCTGCTCCATTTATACAGATA
3' ss Score
8.26
5' ss Seq
CTGGTCAGT
5' ss Score
6.6
Exon sequences
Seq C1 exon
GCCATGGCGAGTGTCACTGCGGGGAATGCAAGTGCCATGCAGGTTACATCGGGGACAACTGTAACTGCTCGACAGACATCAGCACATGCCGGGGCAGAGATGGCCAGATCTGCAGCGAGCGTGGGCACTGTCTCTGTGGGCAGTGCCAATGCACGGAGCCGGGGGCCTTTGGGGAGATGTGTGAGAAGTGCCCCACCTGCCCGGATGCATGCAGCACCAAGAG
Seq A exon
ATAATAGAACACGGGCTCTGTGCTGCTGCTGAATGCAGAGATTGTCTAGACCTGGGCCCCAGCCTTCGCTGACTCGGCCATGGCCTCCCATAGCCGTGCTGACCTCCTCCTGCTCAGCCCCGCATGCTCCACCAGAGTGCAAATGAGAGGGAATTACAGAATGATGCCCCTGGAAAGCAGGAGTGACATTTGCTCTTGGAGTTTGCTGGAGAAACAGCTGTGTCATCATTACCCATGCTAAGGAGGAAGGGACACAGAGGATCAGAAACAAATCATAATACAAACGTCGCTTCTCTTTGGCTGAGGAACGCATCTGTGATTTTCTCTTGGCAGATTTCCCTTCCAAATGTCTGGCTCGGGCTGATAATGAAATGAGTTCATGCTCCCTGCGCCTGCAGCGGCTGCTG
Seq C2 exon
ATTGCGTCGAGTGCCTGCTGCTCCACTCTGGGAAACCTGACAACCAGACCTGCCACAGCCTATGCAGGGATGAGGTGATCACATGGGTGGACACCATCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000082781_CASSETTE2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF079748=EGF_2=PD(64.5=26.7),PF079657=Integrin_B_tail=PU(4.7=5.3)
A:
NO
C2:
PF079657=Integrin_B_tail=FE(40.0=100)
Main Inclusion Isoform:
ENST00000296181fB17793
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCATGGCGAGTGTCACTG
R:
GGTGTCCACCCATGTGATCAC
Band lengths:
318-725
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains