HsaEX1018358 @ hg38
Exon Skipping
Gene
ENSG00000173826 | KCNH6
Description
potassium voltage-gated channel subfamily H member 6 [Source:HGNC Symbol;Acc:HGNC:18862]
Coordinates
chr17:63542241-63543660:+
Coord C1 exon
chr17:63542241-63542434
Coord A exon
chr17:63542690-63542985
Coord C2 exon
chr17:63543576-63543660
Length
296 bp
Sequences
Splice sites
3' ss Seq
TTATTATCCCCAATTTTCAGATG
3' ss Score
9.25
5' ss Seq
AAGGTATAA
5' ss Score
7.08
Exon sequences
Seq C1 exon
GAAAGAATGACATCTTTGGGGAACCCGTCAGCCTCCATGCCCAGCCAGGCAAGTCCAGTGCAGACGTGCGGGCTCTGACCTACTGCGACCTGCACAAGATCCAGCGGGCAGATCTGCTGGAGGTGCTGGACATGTACCCGGCCTTTGCGGAGAGCTTCTGGAGTAAGCTGGAGGTCACCTTCAACCTGCGGGAC
Seq A exon
ATGAGGAAACTGAGGATTAGAGACAATAAATAAATTGGCCAAAGCCATTCAGCTAGTCAACGGCAGAGCCAAAATGTGAATTTAATTTGTCTGACTCCAAAGCCCAGGCATTCCTACTACATCATACCAAGCTGAAAAAGGGGGTGCCTTCTGTCCAGAGGGCTCACAGTGCCAGACACAGGGGCTGCCAAGAGGTGACAAAGCTGTCTCTTCTCATGCTCATCCCTCAGTAGAGGAGATTTTGACAACTCAAGAAAAATAAAGAGCCACAAAGTAAAACAGCCAAAGTCACGAAG
Seq C2 exon
GCAGCCGGGGGTCTCCACTCATCCCCCCGACAGGCTCCTGGCAGCCAAGACCACCAAGGTTTCTTTCTCAGTGACAACCAGTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000173826_MULTIEX1-1/4=C1-2
Average complexity
C1*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.802
Domain overlap (PFAM):
C1:
PF0002724=cNMP_binding=PD(53.4=72.3)
A:
NO
C2:
NO
Main Inclusion Isoform:
ENST00000456941fB17982
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAAGAATGACATCTTTGGGGAACC
R:
GACTGGTTGTCACTGAGAAAGA
Band lengths:
276-572
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains