HsaEX1022024 @ hg38
Exon Skipping
Gene
ENSG00000134013 | LOXL2
Description
lysyl oxidase like 2 [Source:HGNC Symbol;Acc:HGNC:6666]
Coordinates
chr8:23316949-23320052:-
Coord C1 exon
chr8:23319885-23320052
Coord A exon
chr8:23318523-23318659
Coord C2 exon
chr8:23316949-23317114
Length
137 bp
Sequences
Splice sites
3' ss Seq
CCAGATATTTTTCTTCCCAGTCA
3' ss Score
5.09
5' ss Seq
GAGGTGGGT
5' ss Score
7.07
Exon sequences
Seq C1 exon
CTGCGCCTGAACGGCGGCCGCAATCCCTACGAGGGCCGAGTGGAGGTGCTGGTGGAGAGAAACGGGTCCCTTGTGTGGGGGATGGTGTGTGGCCAAAACTGGGGCATCGTGGAGGCCATGGTGGTCTGCCGCCAGCTGGGCCTGGGATTCGCCAGCAACGCCTTCCAG
Seq A exon
TCAGCTCATTCCTAAGACACCTGGGCCTCAGCTGGGGTCTTGAAATAGGCCTGGGACTGACATTTGTACCAAATCTGCCACTGATTACAAGCCCCATCCCTTCTCAAGTCCTCATTTTTTTCATCTGGAGGATGGAG
Seq C2 exon
GAGACCTGGTATTGGCACGGAGATGTCAACAGCAACAAAGTGGTCATGAGTGGAGTGAAGTGCTCGGGAACGGAGCTGTCCCTGGCGCACTGCCGCCACGACGGGGAGGACGTGGCCTGCCCCCAGGGCGGAGTGCAGTACGGGGCCGGAGTTGCCTGCTCAGAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134013_MULTIEX2-7/7=6-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0053013=SRCR=PU(48.6=92.9)
A:
PF0053013=SRCR=PD(5.3=60.0)
C2:
PF0053013=SRCR=PD(49.5=94.6)
Main Inclusion Isoform:
ENST00000389131fB18949
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGAAACGGGTCCCTTGTGTG
R:
TACTGCACTCCGCCCTGG
Band lengths:
252-389
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains