HsaEX1024853 @ hg38
Exon Skipping
Gene
ENSG00000095777 | MYO3A
Description
myosin IIIA [Source:HGNC Symbol;Acc:HGNC:7601]
Coordinates
chr10:26202964-26212527:+
Coord C1 exon
chr10:26202964-26203107
Coord A exon
chr10:26204085-26204264
Coord C2 exon
chr10:26211843-26212527
Length
180 bp
Sequences
Splice sites
3' ss Seq
ATCTTTATTTGCTTTTTCAGAAT
3' ss Score
10.72
5' ss Seq
TGAGTTAGT
5' ss Score
-1.34
Exon sequences
Seq C1 exon
TCAGGGAAAATTATTAGATTTGGAAGATTTCTATTATAAGGAATTTTTGCCCAGTCGTTCTGGACCAAAGGAACATAGCCCTAGTTTAAGAGAACGAAGACCACAGCAAGAACTCCAGAATCAATGTATTAAGGCTAATGAAAG
Seq A exon
AATCCATCTAAACTATGATATTTGCCCTTTGCCTCCAAAAGAAGATGTGCTCTTCCATCTTGGGATCCAGCACTGTAACATGTTGGAGCTTAGAGATGTTCTAGTCTAATCTCAGAGCTCTGTACAGAAGAACACCAAATGCCAGAAAGATTAAGTGATTTGCCCAAGATCACACACTGA
Seq C2 exon
GTGCTGGGCGGCGGAGAGCCCCGAGAAGGAGGAGGAGAGAGAGCCAGCAGCCAACCCCTACGACTTCAGGAGGCTCCTGCGCAAAACCTCCCAGCGCCGGCGCCTCGTCCAGCAGTCCTAACCGTTCAACGAGGCAGTCACCGCCGTCGGAAGGCGCTGGAGCCTGCGGGGCAGCAGGGGCCAAGCAGGCACTCTGGGGCTGGCACCAGCAGGCACTGAAGCTGCGGCCCTGATCTCCGCAGAGGCTGCCTGCTGCGCTCGGCCCTCAAGTGCCCGGGCCGGCCTTCGTGCTCCGAAACAAGAGACCTGGGAGCCCTCGGGAAACCTCCCCCGACGCTCTCTCTCGGAACTCCCGCACCCTCCTTTCTCACCAGCCCGCCAGTTGTGGCAACCCTGTCCTTGTTCCCCTAATCTATCACTTTGTTCTTTTTTTTTGTGACTCCTGTGGACTCCACTGCGCCTGGGATCTCGCCAACCCCTCTCTCATTTGGGGTGACTGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000095777-'71-75,'71-74,72-75
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.442 A=0.000 C2=0.776
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0006316=Myosin_head=PD(0.4=1.4)
Main Inclusion Isoform:
ENST00000265944fB20564
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGAATTTTTGCCCAGTCGTTCT
R:
CTGCCTCGTTGAACGGTTAGG
Band lengths:
243-423
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains