HsaEX1024860 @ hg38
Exon Skipping
Gene
ENSG00000071909 | MYO3B
Description
myosin IIIB [Source:HGNC Symbol;Acc:HGNC:15576]
Coordinates
chr2:170235991-170335450:+
Coord C1 exon
chr2:170235991-170236136
Coord A exon
chr2:170319336-170319587
Coord C2 exon
chr2:170335385-170335450
Length
252 bp
Sequences
Splice sites
3' ss Seq
GTTCTTTTTCACCATTTTAGGCT
3' ss Score
10.22
5' ss Seq
GAGGTGAGA
5' ss Score
7.66
Exon sequences
Seq C1 exon
GTCATTGCCTGTGAGCAGCAGTATGACTCTTCCTATGACGCTCGCTGTGACGTCTGGTCCTTGGGGATCACAGCTATTGAACTGGGGGATGGAGACCCTCCCCTCTTTGACATGCATCCTGTGAAAACACTCTTTAAGATTCCAAG
Seq A exon
GCTGCCTCCATCCCACCCCAATGATGGTGAAAAGTATAATTGTTGAAATGAAAAAAATTAATTATGGATCTCATCAGATTTGAGATGGTAAAAGAAAGAATTAGTGAATCTGAAGAGAGATCTATAGAAATTAACCAACCTGAAGAACACAGAGGGAAAAAAAGACATTGAAGAAAAATTAACAGAGCTACAAAGACCCATGAGACACCATAATGCATTACAACATACATGTAAAGGAACTTCCAGAAGGAG
Seq C2 exon
AAATCCTCCACCTACTTTACTTCATCCAGAAAAATGGTGTGAAGAATTCAACCACTTTATTTCACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000071909_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.003 A=0.667 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(18.0=100)
A:
PF0006920=Pkinase=PD(4.7=68.8)
C2:
PF0006920=Pkinase=FE(8.2=100)
Main Inclusion Isoform:
ENST00000408978fB20570
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCATTGCCTGTGAGCAGCAG
R:
AAAGTGGTTGAATTCTTCACACCA
Band lengths:
204-456
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains