HsaEX1027409 @ hg38
Exon Skipping
Gene
ENSG00000128655 | PDE11A
Description
phosphodiesterase 11A [Source:HGNC Symbol;Acc:HGNC:8773]
Coordinates
chr2:177623252-177663949:-
Coord C1 exon
chr2:177663866-177663949
Coord A exon
chr2:177656532-177656675
Coord C2 exon
chr2:177623252-177629562
Length
144 bp
Sequences
Splice sites
3' ss Seq
TTCTGTCTCTTCCCCATTAGACG
3' ss Score
6.88
5' ss Seq
GAAGTAAGC
5' ss Score
6.95
Exon sequences
Seq C1 exon
GCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCATCTGCATGCCTTTGTATCAG
Seq A exon
ACGGGTTTCCTGGAGCCACCATATTCCTGGCACCTAGCACAGTGCTAGCACATTAGAGCTGCTCAGCCAATGTTTGTTGAACAAAGGAATGAAGAAACAGAAAAGTGAATGATGGGATGCAGTATAAGCAGTGGAATGTATGAA
Seq C2 exon
GCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGAAGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCCTCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAACTAAACCTCCAGGTCAGCTGCAGCTGCAAAATGACTACAGCCTGAAGGGCCATTTTCAGTCCAGCAATGTCATCCTTTTGTTCTTTTAGCTCAGAAAGACCTAACATCTCAAGGATGCACTGGGAAGCATGCCTGGGCTTTCACCTTGAAGCATGGTCAGCAGCAGAGAGAGCAACGGGAAGGACAAAGAAAGAGGTGGGGCAGGGAGCACACCCCAGGACCCTCACTTTTCCCTAATGAACACGCATGGGCTGAAATGAAGGCTCTGGGTAGGGGACTGTTTTGGATCCAAGGACCTGTGGACAGTCGGCCTACTTACTCTGAGCTGAGGGAACACTGAACAGTAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000128655_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.176
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=FE(11.2=100)
A:
PF0023314=PDEase_I=PD(1.3=18.8)
C2:
PF0023314=PDEase_I=PD(7.9=36.5)
Main Inclusion Isoform:
ENST00000286063fB22182
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGGATGAACTGCCTCGGTTG
R:
GCTGTAGTCATTTTGCAGCTGC
Band lengths:
256-400
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains