HsaEX1027411 @ hg38
Exon Skipping
Gene
ENSG00000128655 | PDE11A
Description
phosphodiesterase 11A [Source:HGNC Symbol;Acc:HGNC:8773]
Coordinates
chr2:177669493-177675518:-
Coord C1 exon
chr2:177675455-177675518
Coord A exon
chr2:177673469-177673698
Coord C2 exon
chr2:177669493-177669567
Length
230 bp
Sequences
Splice sites
3' ss Seq
GTGATTCATTCTCCCTCCAGCAG
3' ss Score
8.46
5' ss Seq
GTGGTGAGT
5' ss Score
8.95
Exon sequences
Seq C1 exon
ATCAATGTTAATGACAGCCTGTGACCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAG
Seq A exon
CAGACAAAATATACCCATCCTTCCTCCAAGAAAGACAACCCAAATGTCCCATCAGTCACGGCATCAAACTCTTAAGTCCAGGATCTCTGGGAGATACATGCTAGTCTCTACAACAGATCTGGATGCAGATTAAAGACCTACACACACCCAAAATACAGAGTCCAACATGCACCCAAAGACTCCCATTCGGAAAGGGAAGAGATGAGCGATATTCATAGCAATGTGGAGTG
Seq C2 exon
GTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAGATTAGAGCTCAAACTCACTCCTTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000128655_MULTIEX2-1/2=C1-2
Average complexity
C1*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=1.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=FE(12.1=100)
A:
PF0023314=PDEase_I=PD(2.9=20.0)
C2:
PF0023314=PDEase_I=FE(10.0=100)
Main Inclusion Isoform:
ENST00000358450fB22184
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTAATGACAGCCTGTGACCTTGG
R:
TGAAGGAGTGAGTTTGAGCTCT
Band lengths:
132-362
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains