HsaEX1028307 @ hg38
Exon Skipping
Gene
ENSG00000065243 | PKN2
Description
protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:9406]
Coordinates
chr1:88771663-88784824:+
Coord C1 exon
chr1:88771663-88771879
Coord A exon
chr1:88779151-88779212
Coord C2 exon
chr1:88784639-88784824
Length
62 bp
Sequences
Splice sites
3' ss Seq
TCTCTGCTCCCTCCTTACAGCAG
3' ss Score
11.53
5' ss Seq
AAGGTAAGT
5' ss Score
11
Exon sequences
Seq C1 exon
GCTCAAGCAAGATTTAATGAATCAAGTCAGAAGTTGGACCTTTTAAAGTATTCATTAGAGCAAAGATTAAACGAAGTCCCCAAGAATCATCCCAAAAGCAGGATTATTATTGAAGAACTTTCACTTGTTGCTGCATCACCAACACTAAGTCCACGTCAAAGTATGATATCTACGCAAAATCAATATAGTACACTATCCAAACCAGCAGCACTAACAG
Seq A exon
CAGGCTGCCATCTTCAATACTGCCCCCAAGGTATTGGGAGTGAAGGGAGGGATGAGGCAAAG
Seq C2 exon
GTACTTTGGAAGTTCGTCTTATGGGCTGCCAAGATATCCTAGAGAATGTCCCTGGACGGTCAAAAGCAACATCAGTTGCACTGCCTGGTTGGAGTCCAAGTGAAACCAGATCATCTTTCATGAGCAGAACGAGTAAAAGTAAAAGCGGAAGTAGTCGAAATCTTCTAAAAACCGATGACTTGTCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000065243_MULTIEX3-1/2=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
No structure available
Features
Disorder rate (Iupred):
C1=0.157 A=0.000 C2=0.264
Domain overlap (PFAM):
C1:
PF0218511=HR1=PD(43.8=43.8)
A:
NO
C2:
NO
Main Inclusion Isoform:
ENST00000370521fB22684
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCACTTGTTGCTGCATCACCA
R:
ATCTTGGCAGCCCATAAGACG
Band lengths:
132-194
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains