HsaEX1040763 @ hg38
Exon Skipping
Gene
ENSG00000156299 | TIAM1
Description
T-cell lymphoma invasion and metastasis 1 [Source:HGNC Symbol;Acc:HGNC:11805]
Coordinates
chr21:31182421-31187087:-
Coord C1 exon
chr21:31187001-31187087
Coord A exon
chr21:31185738-31185988
Coord C2 exon
chr21:31182421-31182645
Length
251 bp
Sequences
Splice sites
3' ss Seq
TTTATCCTCTCGCCGTTTAGGAG
3' ss Score
8.85
5' ss Seq
ATTGTGAGT
5' ss Score
7.35
Exon sequences
Seq C1 exon
GGTTTTCACTTTCTTCTGTGGAAGAAGATGGTATTCGAAGGCTGTACGTGAATAGTGTGAAGGAAACCGGTTTAGCTTCCAAGAAAG
Seq A exon
GAGGCCAGAAGTCTGAAATTAAGGTATTGGCAAGATTGATTTCTCTGAAGCCTCTGAGGGAAGAATGGCTTCATGCCTCCTTCTGGTTTCTGGTGTGAAAGCAGCACTTGGCATTCTGTGGCTTATGGCTGTATCACTCCAATCTCTGCCTGAAGTCACATGGCTTCTGCCCTGTGTGTGTCTCTGTGTCATTAACATGGCTTTCTTATAAGAACACCAGTCATTGGATTTAGGACCTACACTAAATCATT
Seq C2 exon
GCCTGAAAGCAGGAGATGAGATTCTTGAGATCAATAATCGTGCTGCTGACGCCCTGAACTCTTCTATGCTCAAAGATTTCCTCTCACAGCCCTCGCTGGGCCTCCTGGTGAGGACCTACCCCGAGCTGGAGGAAGGAGTGGAGCTGCTGGAAAGCCCGCCCCACCGAGTGGACGGCCCTGCCGACCTTGGCGAGAGCCCCCTCGCCTTTCTCACCAGCAACCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000156299_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.007 A=0.000 C2=0.421
Domain overlap (PFAM):
C1:
PF0219610=RBD=PD(18.9=46.7),PF0059519=PDZ=FE(35.8=100)
A:
NO
C2:
PF0059519=PDZ=PD(45.7=48.7)
Main Inclusion Isoform:
ENST00000286827fB28057
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGAAGAAGATGGTATTCGAAGGC
R:
CTGGGTTGCTGGTGAGAAAGG
Band lengths:
294-545
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains