HsaEX1040882 @ hg38
Exon Skipping
Gene
ENSG00000146872 | TLK2
Description
tousled like kinase 2 [Source:HGNC Symbol;Acc:HGNC:11842]
Coordinates
chr17:62565001-62576775:+
Coord C1 exon
chr17:62565001-62565137
Coord A exon
chr17:62565811-62566056
Coord C2 exon
chr17:62576709-62576775
Length
246 bp
Sequences
Splice sites
3' ss Seq
CATTTCTTCTGGATCCACAGAAA
3' ss Score
6.76
5' ss Seq
CAGGTATTT
5' ss Score
7.51
Exon sequences
Seq C1 exon
TCAAAACAAGAGAAGATGGCGTGTAGAGATAAGAGCATGCAAGACCGCTTGAGACTGGGCCACTTTACTACTGTCCGACACGGAGCCTCATTTACTGAACAGTGGACAGATGGTTATGCTTTTCAGAATCTTATCAA
Seq A exon
AAAAATGAAATGTGAAAGGACCTGAGAAAGAATTTCCTGAGATAAGTTTAGGTATAAAGCAGAATAAAACCACTGAAGAACTTTATAGGACATGTTCCTGGGATTATTTAAGGAGACAGTGTCCAGTCATCAGAGAGTCACTTCCTGGAAGGCAGTGGTGACCAGCCCCACTGTGTGTGCCTGTGTGCAGCTTGGAATCTTGAACATTCATTGTCTTTGTCATAACTTTTGATTTGAAACATTCAG
Seq C2 exon
GTTAACGTTAGCAGAATACCATGAACAAGAAGAAATCTTCAAACTCAGATTAGGTCATCTTAAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000146872_MULTIEX2-9/22=8-12
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.440 A=0.000 C2=0.086
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
ENST00000326270fB28138
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAAAACAAGAGAAGATGGCGTGT
R:
AGATGACCTAATCTGAGTTTGAAGA
Band lengths:
196-442
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains