HsaEX1041380 @ hg38
Exon Skipping
Gene
ENSG00000186452 | TMPRSS12
Description
transmembrane protease, serine 12 [Source:HGNC Symbol;Acc:HGNC:28779]
Coordinates
chr12:50858785-50872521:+
Coord C1 exon
chr12:50858785-50859053
Coord A exon
chr12:50859237-50859430
Coord C2 exon
chr12:50872421-50872521
Length
194 bp
Sequences
Splice sites
3' ss Seq
ACCTTTTTTTTTTTTTCCAGACA
3' ss Score
11.15
5' ss Seq
CTGGTCTTG
5' ss Score
-6.11
Exon sequences
Seq C1 exon
CGATCCTTTAATGTGGACAGCTGTGATTGGAACTAATAATATACATGGACGCTATCCTCATACCAAGAAGATAAAAATTAAAGCAATCATTATTCATCCAAACTTCATTTTGGAATCTTATGTAAATGATATTGCACTTTTTCACTTAAAAAAAGCAGTGAGGTATAATGACTATATTCAGCCTATTTGCCTACCTTTTGATGTTTTCCAAATCCTGGACGGAAACACAAAGTGTTTTATAAGTGGCTGGGGAAGAACAAAAGAAGAAG
Seq A exon
ACAGAGTCTTGCTCTGTTGCCCAGGATGGAGTGCAGTGGCACGATCTCGGCTCACTGCAGCCTCCACCTCCCAAGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGACATGCGCCACCATGCCCTGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCTCCATGTTGGTCAGGCTG
Seq C2 exon
GAGAATGGCGTGAACCCGGGAAGCGGAGCTTGCAGTGAGCCGAGATTGCGCCACTGCAGTCCGCAGTCTGGCCTGGGCGACAGAGCGAGACTCCGTCTCAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186452-'2-4,'2-3,3-4
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=NA
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(38.1=100)
A:
PF0008921=Trypsin=PD(8.4=35.1)
C2:
NA
Main Inclusion Isoform:
ENST00000398458fB28427
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGACGCTATCCTCATACCAAGA
R:
CCGGGTTCACGCCATTCTC
Band lengths:
242-436
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains