HsaEX6016862 @ hg19
Exon Skipping
Gene
ENSG00000128655 | PDE11A
Description
phosphodiesterase 11A [Source:HGNC Symbol;Acc:8773]
Coordinates
chr2:178540176-178545631:-
Coord C1 exon
chr2:178545554-178545631
Coord A exon
chr2:178542609-178542675
Coord C2 exon
chr2:178540176-178540246
Length
67 bp
Sequences
Splice sites
3' ss Seq
AAATTGTTTTACAACTACAGAAC
3' ss Score
4.9
5' ss Seq
GAGGTATGT
5' ss Score
9.81
Exon sequences
Seq C1 exon
GAGGAGAACTGAATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCG
Seq A exon
AACAAATCAAGAAGATAATGATTGTCACAAGATTATTATTGAAATAATTTTGGCATATAGAGGAGAG
Seq C2 exon
ATCAATGTTAATGACAGCCTGTGACCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGCAAGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000128655-'26-34,'26-30,27-34=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=FE(10.8=100)
A:
NA
C2:
PF0023314=PDEase_I=PU(20.4=95.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACTGAATTCTTTGAACTTGTCAGT
R:
CACTTGCCTGTCTGGAGATCT
Band lengths:
143-210
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)