HsaEX6036987 @ hg19
Exon Skipping
Gene
ENSG00000185842 | DNAH14
Description
dynein, axonemal, heavy chain 14 [Source:HGNC Symbol;Acc:2945]
Coordinates
chr1:225576081-225580153:+
Coord C1 exon
chr1:225576081-225576193
Coord A exon
chr1:225577436-225577575
Coord C2 exon
chr1:225579993-225580153
Length
140 bp
Sequences
Splice sites
3' ss Seq
TGTGGTCTGCCTTCCACTAGGTA
3' ss Score
10.87
5' ss Seq
AAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
AAACACGCCTACAGATCTTGTAAGCCACTGAGTTCCTGGATTGATGATCTCATCCAGCGACTGAATTTCTTCAATACTTGGGCCAAAGTGGCTTATACTGCAATACAGCGTCG
Seq A exon
GTATATGAGATTTGTCACAGTTTGGAAGCAGTCTATTCCATCAACTAGCCAAAAATGCAAACACCCTGAGGATTCAGAGAACAATTTCTTTGAAGGGTTTCCTTCAAGATACTGGCTCCCAGCTTTCTTCTTTCCACAAG
Seq C2 exon
CCTTTCTTGCTGCTGTGCTTCAAGACTATGGGAGGTCCCGAGGAATCGCTGTGGATGCCCTCACCTTCACCCACCATGTGATTTCCAACACCACTGACAAGGATGAGAAGTTCTCCGTATTTATGCCAAAGAAACTCAACATAGTCAGGAGAGCGTTTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185842-'114-120,'114-118,115-120=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.042 C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(16.5=100)
A:
PF0302810=Dynein_heavy=PD(2.2=10.4),PF0302810=Dynein_heavy=PU(16.7=70.8)
C2:
PF0302810=Dynein_heavy=FE(26.2=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCACTGAGTTCCTGGATTGA
R:
ACGCTCTCCTGACTATGTTGAGT
Band lengths:
246-386
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)