HsaEX6065075 @ hg19
Exon Skipping
Gene
ENSG00000175899 | A2M
Description
alpha-2-macroglobulin [Source:HGNC Symbol;Acc:7]
Coordinates
chr12:9232235-9241847:-
Coord C1 exon
chr12:9241796-9241847
Coord A exon
chr12:9232690-9232773
Coord C2 exon
chr12:9232235-9232411
Length
84 bp
Sequences
Splice sites
3' ss Seq
TGATTTGCTTATTTCTCTAGGTG
3' ss Score
10.48
5' ss Seq
TGGGTGAGT
5' ss Score
8.73
Exon sequences
Seq C1 exon
CCTGAAGGACTAGAGAAGGAAACAACATTCAACTCCCTACTTTGTCCATCAG
Seq A exon
GTGGTGAGGTTTCTGAAGAATTATCCCTGAAACTGCCACCAAATGTGGTAGAAGAATCTGCCCGAGCTTCTGTCTCAGTTTTGG
Seq C2 exon
GAGACATATTAGGCTCTGCCATGCAAAACACACAAAATCTTCTCCAGATGCCCTATGGCTGTGGAGAGCAGAATATGGTCCTCTTTGCTCCTAACATCTATGTACTGGATTATCTAAATGAAACACAGCAGCTTACTCCAGAGATCAAGTCCAAGGCCATTGGCTATCTCAACACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175899-'34-41,'34-40,35-41=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.056 A=0.069 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF105694=Thiol-ester_cl=WD(100=51.7),PF076789=A2M_comp=PU(0.4=1.7)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCAACTCCCTACTTTGTCCATCA
R:
GGCCTTGGACTTGATCTCTGG
Band lengths:
182-266
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)