HsaEX6070614 @ hg19
Exon Skipping
Gene
ENSG00000197616 | MYH6
Description
myosin, heavy chain 6, cardiac muscle, alpha [Source:HGNC Symbol;Acc:7576]
Coordinates
chr14:23863277-23866026:-
Coord C1 exon
chr14:23865903-23866026
Coord A exon
chr14:23865493-23865629
Coord C2 exon
chr14:23863277-23863532
Length
137 bp
Sequences
Splice sites
3' ss Seq
CATCTACCCCTTGCCTGCAGGTG
3' ss Score
10.15
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
Exon sequences
Seq C1 exon
GTATCGCATCCTGAACCCAGTGGCCATCCCTGAGGGACAGTTCATTGATAGCAGGAAGGGGACAGAGAAGCTGCTCAGCTCTCTGGACATTGATCACAACCAGTACAAGTTTGGCCACACCAAG
Seq A exon
GTGTTCTTCAAGGCAGGGCTGCTTGGGCTGCTGGAGGAGATGCGGGATGAGAGGCTGAGCCGCATCATCACGCGCATGCAGGCCCAAGCCCGGGGCCAGCTCATGCGCATTGAGTTCAAGAAGATAGTGGAACGCAG
Seq C2 exon
GGATGCCCTGCTGGTAATCCAGTGGAACATTCGGGCCTTCATGGGGGTCAAGAATTGGCCCTGGATGAAGCTCTACTTCAAGATCAAGCCGCTGCTGAAGAGCGCAGAGACGGAGAAGGAGATGGCCACCATGAAGGAAGAGTTCGGGCGCATCAAAGAGACGCTGGAGAAGTCCGAGGCTCGCCGCAAGGAGCTGGAGGAGAAGATGGTGTCCCTGCTGCAGGAGAAGAATGACCTGCAGCTCCAAGTGCAGGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197616-'18-20,'18-19,19-20=AN
Average complexity
A_S
Mappability confidence:
88%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.070
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(6.0=100)
A:
PF0006316=Myosin_head=PD(0.4=6.5)
C2:
PF0157614=Myosin_tail_1=PU(27.0=61.6)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGGAAGGGGACAGAGAAGCT
R:
CGGACTTCTCCAGCGTCTCTT
Band lengths:
249-386
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)