HsaINT0000035 @ hg38
Intron Retention
Gene
ENSG00000175899 | A2M
Description
alpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7]
Coordinates
chr12:9112377-9113543:-
Coord C1 exon
chr12:9113360-9113543
Coord A exon
chr12:9112537-9113359
Coord C2 exon
chr12:9112377-9112536
Length
823 bp
Sequences
Splice sites
5' ss Seq
GCTGTGAGT
5' ss Score
7.39
3' ss Seq
GGATCGGTCCTGTATTTCAGGTC
3' ss Score
8.58
Exon sequences
Seq C1 exon
GCAGTATATGGTTCTGGTCCCCTCCCTGCTCCACACTGAGACCACTGAGAAGGGCTGTGTCCTTCTGAGCTACCTGAATGAGACAGTGACTGTAAGTGCTTCCTTGGAGTCTGTCAGGGGAAACAGGAGCCTCTTCACTGACCTGGAGGCGGAGAATGACGTACTCCACTGTGTCGCCTTCGCT
Seq A exon
GTGAGTGTGGCTGTTTGACTTAATATACTTGGTTCTTTTAGTCAGGGTCATAGGGATCTAGTATTCTGTCAGATGAGGCTTTGGGAGGTTGGTAAGAACTGCAGGAAGGAATCCAAATGTAGCAAACTAAGTATAGAAATTAAGGAGCAATGCATGACTCTCCAGCCATGGGAGACAAATATTTACAGGCAAACTAAAAGTCAGCTTAATAATCACATAGAAACCCTATTAGCCAGAAAGGAAAAAAAAAAAAAGAAAATGTGACTTCTTAAAATTAAGATGGAAAAAATATTAATAAAGCAAACTAGACCAAGGCTCAACATGAGCCACCCGTGGTGGACTGACAGGAACACATCACTCCACACTACTTCTAAGAGTAAAAATTGTAGAAATTACCCTGAGCAAAGGTGTAATATCTCTTCAGAGTTGTCCACATGTGAGATGCTTACAGCCTAGTGTCAGTAAAATACGGGGTTTTTTTCCATAGCCTGTAAAACATGCTTCGACCATGCCCTTTTAGCATGTAATATCAGCCTGGTAAAGCTCAGCGTATAATTGAATCAAGACTGTTTCTGTGAGCTGTATGAAGGTGTGAATCTCACTTACAACCTCTCTTACTGATTTATTTTCCTCCACCTTGTGTCCTGTCTCCCCATTTGTAAAATGGCAGAAGTGATTCCTGTCCATGCCAACTTTCCCTGCTGAGAACAAGGGAGTGAAGTTAAGTAAGAAGGGCAAGATCTCCAGGGAAGAGTGCAACAGCAAATAGGGGAGGAGACCTGCGGGTGCTGAATGGGGTTTCAGGATCGGTCCTGTATTTCAG
Seq C2 exon
GTCCCAAAGTCTTCATCCAATGAGGAGGTAATGTTCCTCACTGTCCAAGTGAAAGGACCAACCCAAGAATTTAAGAAGCGGACCACAGTGATGGTTAAGAACGAGGACAGTCTGGTCTTTGTCCAGACAGACAAATCAATCTACAAACCAGGGCAGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175899:ENST00000318602:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.014
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0183514=A2M_N=PU(17.0=29.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAGTATATGGTTCTGGTCCCC
R:
CTGTCTGCCCTGGTTTGTAGA
Band lengths:
344-1167
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development