HsaINT0000079 @ hg38
Intron Retention
Gene
ENSG00000166535 | A2ML1
Description
alpha-2-macroglobulin like 1 [Source:HGNC Symbol;Acc:HGNC:23336]
Coordinates
chr12:8863794-8868057:+
Coord C1 exon
chr12:8863794-8864008
Coord A exon
chr12:8864009-8867841
Coord C2 exon
chr12:8867842-8868057
Length
3833 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAAC
5' ss Score
7.82
3' ss Seq
CGTTTGGTTGTTTCCCTCAGGAT
3' ss Score
9.17
Exon sequences
Seq C1 exon
GAGAATCCATTTACTGGAGCCAGAAACCTACTCCATCATCGAACGCCAGCCCTTGGTCTGAGCCTGCGGCTGTAGATGTGGAACTCACAGCATATGCATTGTTGGCCCAGCTTACCAAGCCCAGCCTGACTCAAAAGGAGATAGCGAAGGCCACTAGCATAGTGGCTTGGTTGGCCAAGCAACACAATGCATATGGGGGCTTCTCTTCTACTCAG
Seq A exon
GTAAACAGCCTGTTCTCCCACTGCCACTTATCAGGTAGAATTAGATCTTGTGTGGAGATAGAGGAAAACATATTGTCCTTGCCTTCTCGGTCCAGGGGCTTAGAGAGAGGAAAAGCCTGTGAACAATATATGGAAGTATTCATAAAATGGGTTATAAGAGCACATTAATAGTACCAGATGTATTTAATTTTCTTTTTTTTTTTGTTGAATGTGAAACATTGGGGCCGGGCATGGTGGCTCATGCCTGTCATCGCAGCACTTTGAGAGGCCGAGGCAGGCGGATCACCTGAGGTCAGGAGTTCGAGACCAGTCTGGCCAACATGATGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGTGCGATGGCAGGTGCCTGTAATCCCAGCTACTTAGGAGGCTGAGACAGGAGAATCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCATGCCATTGCACTCCAGTCTGGGTGACAAGAGTGAAACTCTGTCTCCAAAAAAAAAAAAAAAAAAAAAGCAACATCATGAGGTCCATGTTTTACATGCAAGTAGGATATATATAATTATGGCTAAATGTACATATTAATAAACTAGGAAGACCATTATGGGGTCTGTAAAGATAACACCAAGATTCATGGGCACATATCCTTCTATCCTTCTTCTGCTATTGCAGGTATTAGAAAGCTAATAAGATATAGTCTGAACTCTAAAAAGTTTACAGTCTAGAAGAAAAGCGAGGACAAAGTCTATGTATTACAAAGAGGATCTGGTTTATAATATAAGAAACATGCAAAAGGTACAACATATCGAATTTCAAAATGGGAGAGAAAGCTCATATCAGCTTGAGGGATAAGAAAAGTCTTAGCCGGGCACAGTGACTCACGCCTATAATCCCAGCACTTTGGCAGCCTGAGGCGGTTGGATCACTGGAGGTCAGGAGTTCAAGATCAGCCTGGTCAACATGGTGAAACCCCATCTCTACTAAAATACAAAAATTAGCTGGATGTGGCCCCATCTCTACTAAAGATACAAAAATTAGCTGGATGTGGTGACATGTTCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGAAGAATTGCTTGAACCCGGAAGGCAGAGGTTGCAGTGAGCTGAGATCGTGCCACTGCACTCCAGCCTGAGTGACAAAGCAGCACTCTGTGTCAACAACAACAATAAACAAAAACAAACAAAAACAACAACAAACAAAAATTTTTTAGGCTGGACACAGCAGCTCATGCCTGTAATCCCAGTGCTTTGGGAGGCCGAGGCAGGCGGATCACCTGAGGTCGGGAGTTCGAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCAGGCGTGGTGGCGGGTGCCTGTAATCCCAGCTACCTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTTGCGGTGAGCCGAGATGGCGCCATTGCACTCCAGCCTGGGCAACAAGAGTTAAAACTCCGTCTCAACAACAACAACACAACAACAACAACAACAATTTTAACTTTGTTTCAGAAAGATTAATCAGCCACTTGGTGTGTGAGATAATTTAGAGAGGAGAAACATTGGACTTGAAGAGATCAGGAGACTGTTTCCTTTATCTAGGTTAGGGGTAAGGGGAAATTGGGAAATTGAATGAGTGGTGTGGCAGTATGGAAAAAACAGAGGGGTAGAATTGTATGATAAACTCAAATCATAAAAAATTATTTTAGATTATAATGAAGAGAGTAGTCATTAATCTATGTATTCTGAAAATATTAAATATCTACCATGTCCAAATCACTTTGATGAGGCTACAGAAATAACTAAGAAAATATATTTCTTGTTCTCATGAAGATTATATTCTGATTTGTTGAAATTAGCCAATTTCACTGAAGATATAACATGTAAATCAGACCTGAAAGAATGAACATCTTTTAATAGGTTGCATGTTTGGTAAAAATGTTAAAAGCACCAAGTTTAGGCCAGGTGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACGAGGTCAGGAGATCGAGACCACGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCCGGGCACAGTGGTGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGGAGGCAGAGCTTGCAGTGAGCCAAGATCGCGCCACTGCACTCCAGCCTGGGAGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAGCACCAAGTTTAAATATGGTAATGACTTAATTGAAACTTAAAAAAATTATATGGTACTATGCCTCCCTGTTTCAGGGAAATTCTTGGCCAAAGATCACAAAATACTCCTTCTTGCTCGGTCCTGAATAATTATAATATATAATAATATTTTTGGAAAGCAGTGGGTGAAATGTTTACAACTCTCAGTGACAGGTATATGTCAGAATCCTTTTTCAATGAAATCCTTGGCTATCACAAGAAGTCATATATCATATATTACCCACACTGGTTTTTCAGCTGACAGTGAGGTCCCTTTCTTTGAATTGTCTCCATATGTTCAAGCAGTAAAAAACCTCCCTGGCTCCAGTCCACAAAAGGTAAACAAAAATTGTTTGTAGATGGTGAAGCTGCACAGATAGAACTTCTTCACAGCTTCACCAGGGTGGGTGACCTGTCTTCCTGTTTTGTAGGACAGTGATAATGTCGAAATAAGAATGTATTTTTCATTTGTGAGATGAAGAAATCGGGTTTTTTTTTGTAATAGATATTTTTTGTAATAGATATTTTACACGAGTGAGATATAACAATTTTGTTGAACACTTCATTCATTTTTCTTTCCCCTTGTAATTTATATGAATTATGTTTTCAGAATGAAACAGTTCAAATATCACTGTACCATGCTCACTTAGTGACAGTTTATCTGTCTTATTCCCAGAGAAATAAAAGATTGTCACATGGTATAATGGCTAAGAAGCCAGCCTGCAGGGAAGGACTTTCCTAGGGTCCCTTATACTCCTTCCAACTGTCATGTAGAAGATCATTACACAGTTAAATGACTTCATAGACTGCAATTTCTAGGGCTATCAAGTTACTACTGTTTCTCCCCCAAATAAGGAAGCTGTAAAATATATACTGAACAATTATCCACTTGCTTCTAGCAATAACTCATTCTGAAACTGTTGGTTTCTGAACATGAATTGATTAGGTTAACCAAGTAATCTGTGGATGTTCAGTAGTACCTTGTTGATGGTGATTTTCTATAAAAGCATGCTACTGGCTGGGTATGGTGGCTCATGCCTGTCATCCCAGCATTTTGGGAGGCCAAGGCAGCCGGACCACCTGAGGTTGGGAGTTCAAGACTAGCCTGACCAACATGGAGAAACCCCTTCTCTACTAAAAATACAAAATTAGCCGGATGTGGTGGCACACGCCTGTAATCCCAGCTACTTGGGAGGCTTAGGGAGGAGAATCACTTGAACCCAGGAAGCGGAGGTTGCAATGAGCTGAGATCGTGCCATTGCACTCCAGCCTGGGCAACAAAAGCAAAACTCCATCTGAAAAAAAAAAAAAGCAAGCTACTGTGATTTCTAGGCCAGCTTCTCCAGAGGAGGTGGGTATAGTTCTCTAAATACTTAAAGAAGTCATCATCCAAGCCAACTAACAACAACCAGATGTGTGGGTTATAGAGTTGTTCAAGGTTAATTCCAATGGCTCACAAAATGGTAAGTATACGTTTGGTTGTTTCCCTCAG
Seq C2 exon
GATACTGTAGTTGCTCTCCAAGCTCTTGCCAAATATGCCACTACCGCCTACATGCCATCTGAGGAGATCAACCTGGTTGTAAAATCCACTGAGAATTTCCAGCGCACATTCAACATACAGTCAGTTAACAGATTGGTATTTCAGCAGGATACCCTGCCCAATGTCCCTGGAATGTACACGTTGGAGGCCTCAGGCCAGGGCTGTGTCTATGTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000166535:ENST00000299698:29
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.083 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF076789=A2M_comp=FE(28.9=100)
A:
NA
C2:
PF076789=A2M_comp=PD(5.3=18.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development