HsaINT0003963 @ hg19
Intron Retention
Gene
ENSG00000160323 | ADAMTS13
Description
ADAM metallopeptidase with thrombospondin type 1 motif, 13 [Source:HGNC Symbol;Acc:1366]
Coordinates
chr9:136313720-136315086:+
Coord C1 exon
chr9:136313720-136313849
Coord A exon
chr9:136313850-136314903
Coord C2 exon
chr9:136314904-136315086
Length
1054 bp
Sequences
Splice sites
5' ss Seq
TCGGTGAGT
5' ss Score
11.11
3' ss Seq
CTGACTCCAGTTTGCTCCAGGTG
3' ss Score
4.45
Exon sequences
Seq C1 exon
GTCTGATGGAGCTGCGTTTCCTGTGCATGGACTCTGCCCTCAGGGTGCCTGTCCAGGAAGAGCTGTGTGGCCTGGCAAGCAAGCCTGGGAGCCGGCGGGAGGTCTGCCAGGCTGTCCCGTGCCCTGCTCG
Seq A exon
GTGAGTGAGGGGAGCAAGACTGTGTGCTGGCCTTCTCCCTGTAAGTGGGAGACCCGAGCCTTGGCTCCATGCCCGGTGACCTGCGGAGGGGGGCAGGTGCTGCTGGCTGTGCACTGTGTGAGGCTGGACCATGGCCGCCCCATCCCCCTGCCTCACTCCAAGTGCAGGCCAGAGCCCCGGCCCAGCCCCTTTGAGGACTGCAACCCAGAGCCCTGCCCTGCCAGGTGGGCCCCTTCCCAAGGAGACAGGGGGTGCTAGGTCTGCATCCTGGCTCTTTCCTCACCTCCAAGCCAGACCTTTTGACCCTCAGTGTCCTCACCAGTGGGAGCAGGTCATTTTGTGCCCCCAGAAGACTGGGGGAGTTTAATGAAAGGATTAGATGCATGTAAAGTACATGCTAAATGCAATGAGTGTAAAATGCATGCTCGATGCAACGCGTGTAAAGTACATTGCACAGGATCTGGGATGCTGTGGGTGCACATGGTTGCTGGTGCGTTTCTTCATCGCCTGCTCTTTATGGAGCACCTAGGCCCCGGGGCCGTCCTGGAGCTAGGGGACACAGCAGAGAACAAGGCAGACAAATGTCCCTGACCTCCTGGAGCAAATGCAGGGGGAAAGGGGGACAGATAATAATAGGACAGGCGGGGAATGCAGTTTGATGGATGGTGTTCAGTGCGATGCAGCCAAACACAGCGGGAGGGGAGGAGGGGAGGGCTGGCGGGGTGGGCTCCAGGGCGGTGGTGCTGGGATCACTGTTGAAGACAGACATGCAGGGCCCTTGGGTGCCCGGACCCCTGCCCCCACTGTCTCTGGGATACGACATCTGTCGTTTGCCCTCACCTTTCTCTTCTGTAAAATGGGTTTGTCCAAATGTTCTGTCCACTCTGCCAAGCCTCTTGGTGAGGACACAAGGGGGCCTCCAGAAAGAGAACCTCTCCGGGCCCTTCCCAGCTTCCTGTCTCTTCCTAGTCTGGGGAAATGAAGGGGAGACCTGGCTCCCCTGGGTTCCCAGGCCCTGGGGCTGTTTGGGGTCCCTGACTCCAGTTTGCTCCAG
Seq C2 exon
GTGGCAGTACAAGCTGGCGGCCTGCAGCGTGAGCTGTGGGAGAGGGGTCGTGCGGAGGATCCTGTATTGTGCCCGGGCCCATGGGGAGGACGATGGTGAGGAGATCCTGTTGGACACCCAGTGCCAGGGGCTGCCTCGCCCGGAACCCCAGGAGGCCTGCAGCCTGGAGCCCTGCCCACCTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160323-ADAMTS13:NR_024514:12
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0009014=TSP_1=WD(100=90.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCTGATGGAGCTGCGTTTCC
R:
CTAGGTGGGCAGGGCTCC
Band lengths:
313-1367
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)