HsaINT0026561 @ hg19
Intron Retention
Gene
ENSG00000165995 | CACNB2
Description
calcium channel, voltage-dependent, beta 2 subunit [Source:HGNC Symbol;Acc:1402]
Coordinates
chr10:18789741-18795476:+
Coord C1 exon
chr10:18789741-18789877
Coord A exon
chr10:18789878-18795399
Coord C2 exon
chr10:18795400-18795476
Length
5522 bp
Sequences
Splice sites
5' ss Seq
CAGGTATGA
5' ss Score
9.46
3' ss Seq
AAATTTTTGCTTTACTCCAGTAA
3' ss Score
5.15
Exon sequences
Seq C1 exon
AAATTTAACAATGACTGGTGGATAGGGCGATTGGTAAAAGAAGGCTGTGAAATCGGATTCATTCCAAGCCCAGTCAAACTAGAAAACATGAGGCTGCAGCATGAACAGAGAGCCAAGCAAGGGAAATTCTACTCCAG
Seq A exon
GTATGAGACAGATGTCAAGTGTTTGCATAAAACTTAGATTATACCACTATCTGTGTACTGTTGTCTGCTGTATTCTGTATCCTTTATTATGTATTAACAAGGAGGCTGGTAATATGGTTTATTGATAGCATCACAAATCTTGCATTTTCCTGCATTTAAAAAACTTCAGTCCAGCACCTGATTTTCACCCTATTTGGGAAAGTGTCAAATTATTATCATTAATGAAAAGAGCTAAGGTCATAGAGTATTAAATTCAGGCTCCAGGGCAGAGGAAAATCTGAAACCTTAATCATTTACTGAAAAATAGTCTGGCACATCATAGCCCTGGTGACTAATCCCACTGTCTGTAGCTGCCTGGTATGGCTGGGAGATGTTTGAGAGATGACATTCTCAGACATCATCAGGCAGTGGCAGCTCTTGTCATCCGTTAGTTTCATTTTCACCTGAGAAACTCAATTTTCAGTTCTACCCACTGTTAAGCACTTAAAGAGAAGCGAAGTATGAAACAAGTTAAAACTGCCTGTGCAGATGGCAATTAGATGAGTTATGTAAGAAGCTGGGGCTGAATAATCCCTCCTAGGATTTGTGAGGTTGTCTGTCCCTCTCTGAAAGAATCACTAGAAAGGCTTCTCGTAGATGTACTGAATTTTCCATGGAATCGTATGCAGACGGGTCTAAGGACGCAGCATGCCTCTCCCAATGTGAAAGGATGGGACATGGGCAAGGCCTTTCTTAAATACGAATCGCTGGATTTCTCTTTTCTCCATCTTACATCTTATTTGTTTATCTAAGATGCAAATCCCTTTGTCAGTGATAATACTTTACTGTGAGCAAGTATTTTTTTCAAGCGTCAGCAGATGAGTGAAACAGAATATGCTTTGTGGTTTGGAACACCCATCCTCATTAACTGGCTTTTCATAATTGTCAAGTTCATTTAGTTCAGACGGATTCCTCTGTGTTTTGAGACCTCCACCCCAGAATTGACTTTCATTAATTCCTGGGTTATTGAGAGCACTCAGATGGTGAGATGCATTCAGTCATATAAAAGTAGAGGCATGCATAAAAAAGAACAAAGATTGGCCGGGCATGGTGGCTCATGCCTGTAATCCCAGCACTGGGAGGCCGAGGCAGACAGATCACCTGAGGTCAGGAGTTCAAGACGAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATCCAAAAATTAGCTGGGCATGGTGGCGGGAGCCTGTAATCCTAGCTACTCGGGAGGCTGAGGCAGGAGAATTACTTGAATCTGGGAGGTGGAAGTTGCAGTGAGCCCAGATTCGTGCCACTGCATTCCAGCCTGGGCGACAGAGTGAGACTCTATCTCAAAAAAAAAAGAACAAGATCATGTCTTTTGCAGCAACATGGATGGAGCCGGAGGCCATTATCCCAAGCAAACTAACACAGGAATAGAAAACCAAATACGGGGGCCACGTGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCATATCACAAGGTTAAGAGATTGAGACCATCCTGGGCAACATTGTGAAACCCCGTCTCTACTAAAAAAAAAAAAAAATTAGCTGGGTATGGTGGTGTGTGCCTATAGTCCCAGCTACTTGAGAAGCTGAGGCAGAGAATCACTTCGAACCCGGGAGGCAGAGGTTGAAGTGAGCCAAGATCGCACCATTGCACTCCAGCCTGGCGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACCGCATGTTTTTACTTATAAGTGAGAGCTAAACATTGAGAACATACACCAGGAAGGGAACATAAGACACTGGGGACTACTTGAGGGTGGAGGATGGGAGGAGGGTGAGGATCAGAAAAACCACCTCCTGGGGCATTATGTTCATTATCTGGGTGACAAAATAATCTGTACACCAAACCCCTGTGACATGCAGTTTACCTGTGTAACAAACCTGGACATGTACCCCGAAACTAAAAGTAAAAAAAGAAAAAAAAGTTGCCTGTAAAGATAACCCTCTTAGGATTAAAATACTTTACTCTGAATTAAGTTATCATTATCATTAGCAGCAGTAAATTATTCATTAGACCAACATACATATAATGCATATTTTGATATGCAATATTAAATATTAAACTTTTGTTGAAAATGCATTTCTTAATGAGAAAAAAAAGTAAAGACATGCAGATGAACAGCGCATGTGCATTCTGCCTGCAGGGTGTTTGAAGACCCGATAGGATTCTTTCAATCCTTAATGTTCCATTGGCCTTATTTTGTGTTTTCCTACCCTCTGTATTGAAAATGGTATCATAATACTAGCTAATGAAACCTTATGGCCAAGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAAGCAGGTGGATCGCTTGAGGCCAGGAGTTCGAGACCAGCCTGGTCAATATGGTGAAACCCTGTCTCTACCAAAAGTATGAAACTAGCTGGGTGTGGTGGTGCACACCTGTAACCCCAGCTACTTGGGAGCCTGAGGTATGAGAATCACTTCAACTTGGAAGGCGGAGGTTGCAGTGAGCCGAGATCATGTTCCAACTTGGGCGTCAGTGAAACTCTGTCTGAAAAAACAAACAAAAAAAAGAACCACCTTATATGGAAACATTTTGTTTTAATAGGGTGTAGACATTGCTCCTGTCAACTAGGTAGTATATCGTTTGTTGAGGTTTGAAGTTATCCCAGCTGGGGGTGTTTTGTTTTTAGTTAGGACAATTCAGCATTTTTCAGAATTTTCTTGTCAAATGACTTGAGAAAGGGGTTCCAAGATGAAATAAATTAAGGATAGTTCTAGGTAATAGAAAGTTACTTCAGGATTTTTTTATAGCCTTTTAATGTCATCATGTACACTGTGAATCTCTGGTGGAATGGGAATTTTTTTAAGTATAGTATTTACTAAAATTGCTTTCTCATAAAAACTCCCCTGGCTCATGTCTTAGGAATAGTGTTTTGTAGAATACATTTTGGAAAATTTGGGATGGATTTTTGCAGAGGCAGGCTTGTGTGTCTTTCTTTGCCTCTTCATATAGAAACTGAGAAATGAGAACAACTTCAAAGGGAGTAGAAATCTTTCCCAAAATTGTTTGAGAAATGTAGTCTCCTGTGTCTCCCAAATGGGCTTGCCTAGGCTAACATTAGTGCTCCACTCATCTTTGTAAGGACCTGTGGGAGCAGTGGGTATTAGATCTTACAGGTCACAGATGAGAAAACAGGTTAAGAGAAGTTAGGGAACTTGATCGAGGTCGCAGAGCTAGTAAGCGTCAGAACCAAGATGGTAGCCTGACCTCCACGCTGTACAGACTTCCATGCTGCACTGCAGATTAAGGAGCCAGGTCTTGCCTGGCACAGCAAGCCCAGGACAGATGGTTATTGCCATCTGTTATTATTTACTTTATTAGATATGTTGTTTTGCTCTTGCATTTTTTTCCCTTAGGACTCTGAGTTATCCGTATTTGAGGGAATGTAACATCTCAGAACTTACTCCAGAGAACTAGATTACCTTTTCTTACAGCCATATATCTTTTCCTTTGATTTTCTTCATTTTATTTTGGCCCAAGATTTTGCCTAAGTATGTGAAAATACTTTTACTTGCTTTCATAGGTTTTTACATTTCTCTCCTTTTGTGTGTGTGTGTGCGTGTGTGTGAGACAGAGCCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCAGTCTCGACTCACTGCAACCTCCGCCTCCCCGGTTCAAGCGATTCTCCTGCTTCAGCCTCCCAAGTAGCTGGGACTACAGGCATGCACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACTGTGTTGGCCAGGCTGGTCTCAAACTCCCAACCTTAGGTGATCCACCCACCTTGGCCTACCAGAGTGTTGGGATTACAGGCGTGAGCCACCGTGCCCGGCCTCTCCTAACATTTTAAATGTAGTTTTGTTTTGAGGACATAACCAGAATCCGGCAGTCTTTAAAAACTCTGATACAGAAATTATAAAAATTGACAGAACTCAATGGAAATGGAATTGGGGTACCGTTCAAGAACTTGGCATTTTAATAGAATTAAAAGTCAAGGACAAATCTGCATCCTGGTCATTGTCACCATTTGCAGCATTTGTCACAATTTTACATAAATAATATTTTGGCTGTTACTAAAATTCAAAGGGAATATAAAACCCATGAACTTAAACTGAAATTAGACTTAATACTTCAGAAAAAAAAAAAAAACTTCTGGGGAAAAAAATGTTTTGGTCTTGGTAATAGGTCCTTGTATAACTGCCAGAAACTGCTTCTATAGATATCACTTGTCATTAATTTCACATACTGTCTGATGCCCTTATTAAATGTATTTGAGTATCTCTTAAGAACCTTAAAAAGATATACAGCCCTCCTGCTAATTGCCTAATAAAGTTTTTGATGTTTATGCATTAAAATGCTAGAACAGTAGCAATAACATTCAGCCTGTTACTGATACTTTAATAAAACTTTTATTTCCATATTAATATTTACGTAAGTAAATATTGCCCTTTGATGCATAAACACTGTAGCAAATTCTTTCAACTAGACCCTGGCTCGGCCATAATAATAAACATTAGGCAGTGAGATCATTTTGCCCAAATGTAAAATGTTCTTCTTATCTTCATCTGAGAGAGGGGTCATTCGGTAACACGTTATTTAGCATGCTAGTAGGCTGGTGAAAAACACAAATGCTGTTGTTCTAATATTAACTCCAATGTTTCTGAGACACTGCAGTATATCATATCAAACTTTCAAATTTGGTAGTTCGGAAATGTATGATCTTCAAATTATTCCTAAATTAACCACGTTTCATTCTCCACGTGAGTCACGCTTGAGAAGTATTCTGGGTACTATCTGATGGCTACATCATATCATATTCTGTTTAGTCATGTTTCTTCGTGTGTCCGTTAGTGGTTGGCAAGTTTTCATATGGCTCTGTTGTTCTTTGATAGATTGCTCATGAAAGCGTGAGTGCTTTCAATCTTAGTGTACTATTAATAAAATAAGCCTAAAACAGAGGAGCTGAAACCAAACAAGAAGGAAATATTAATCTTGGGTGTTAGCCTTAAGGTTCTGTGCATCGCCTCTGAGGGTCTCTAAAATAAAAAGCAAAATAAATCTGTGCTATTTCACTGTCTGTGATCTGGGCAAGTAACTTGGGGGCTGCAGAAATTACACTGGTTCTCTTCCATTCTCTCAGGTCCTTTTAAAATTAAACCTTGAATTTGAAATCAGAGACCATCATGTGGCTATTTCAAGTACTCCAGGAATCTCCACTGGGAAATATTGTTTTCCTCCTTAAATGAAAGATAAATTTAAAGTTGAATAAAACCATAATGAATTATGTTTACTGAATAATATAAATGTTTGAGGATGCGAAATAAGTGTCAGATTTAATAGAAATTTTTGCTTTACTCCAG
Seq C2 exon
TAAATCAGGAGGAAATTCATCATCCAGTTTGGGTGACATAGTACCTAGTTCCAGAAAATCAACACCTCCATCATCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000165995-CACNB2:NM_000724:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.380 A=NA C2=0.838
Domain overlap (PFAM):
C1:
PF0001823=SH3_1=PD(51.2=47.8)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)