HsaINT0027369 @ hg38
Intron Retention
Gene
ENSG00000137225 | CAPN11
Description
calpain 11 [Source:HGNC Symbol;Acc:HGNC:1478]
Coordinates
chr6:44173218-44176151:+
Coord C1 exon
chr6:44173218-44173386
Coord A exon
chr6:44173387-44176067
Coord C2 exon
chr6:44176068-44176151
Length
2681 bp
Sequences
Splice sites
5' ss Seq
GAAGTAAGC
5' ss Score
6.95
3' ss Seq
CCTCCCTCTCTGTTCTGTAGGTC
3' ss Score
11.45
Exon sequences
Seq C1 exon
GCTGAGTGGGTCCTATGAAGCATTGTCAGGGGGCAGTACCATGGAGGGCCTTGAGGACTTCACAGGAGGCGTGGCCCAGAGCTTCCAACTCCAGAGGCCCCCTCAGAACCTGCTCAGGCTCCTTAGGAAGGCCGTGGAGCGATCCTCCCTCATGGGTTGCTCCATTGAA
Seq A exon
GTAAGCAAAGCATGGTCCCACCTCAGGGCCTTTGCACCTGCTGTTGCTGTCACCCAAAAGGCTCTTCCCCCAGTATCTGCACGGCCAGCACCTTCTCATTCAGTTCAACTGCCCTTTCCCCAGACTAGCCTTCCCTACCTCCCCGTCTAAAGTCGCCGTCCCCACCCTATTTACTTTCTTTTTGTTTTTTTTTGTTTGTTTGTTTTGTTTTTTTGAGACAGGGTCTCATTCTGTCTCCCAGGCTGGAGTGCAGTGGCAAGATCTCGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGTGATTCTCCTCCCTCAGCCTCCCAAGGAGCTGGGATTACAGCCGTGTGCCACCCTGCCTGCGTAGTTTTTTGTATTTTTAGTAGAGAAGGGGTTTTGTCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAACTGATCCACCCACCTCGGCCTCCCATAGTGCTGGGATTACAGGCATGAGCCACGGTGCCCAGCCAGCCCTGTTTACTTTCTATCTGGTTTTTACTTTCTCCCCAACATTTATTGTGACCTGAAATTATCTTGCTTATCTATGTTTTCACTCATAGCCCATCTTCTCCAGATAGTAGTCACATTCCATGAGGGCAGTGACCTTCTTTGTCTCATTCACTGCTGGACCCTGGAACTTAGGAAGGAGCCCAGCATGCAATAGGCACCCAACCAACATTTGCTCGACAAAATACATGAACCCAGGGTGCTACATATGACCCTGCATTCTTGGCATTTATCCCAGAGAAATGAAGACATGTCTCCAAAAATGTTTGTACACAAATGTTTACAGCAACTTTATTCATTATAGCCCCGAAACAGGAAACAACCTAGATGTCCTTCAATGAGTAAATGGTTAAACAAACTGTTTATTACACACCGTGGAATACTACTTAGCAATAAAAAAGAACAAACTATTGATACTCAGAGAAACTAGGACAGATCTCAGGGGAATTATGCTGAATGAAAAAAGCCAACCCTAGCCAGGTGCAGTGGCTCATGCCTGTAATTCCAACACTTTGGGAGGCTGAGGTGGGAGAATTGCTTGAACCCAGGTGTTCAAGACCAGCCTAAGAAATATAGTGAGACCTCATCTCTACCAAAAAAAAAAAAAAAAAAGAAATTAATTAGCTGAGAAAAAAGAAAAAAAAAAAGACAATCCCCTCCAAAGGTGGTTACACACTGCATGATTCACGATATTCTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGATGCGATCTCGTTTCACTGCAACATCCACCTCCTGGGTTCAAGAGATTTTCCTCCCTCACCCTCCTGAGTAGCTGGGATTGCAGGCACCTGCTGCCATGCATGGCTAAGTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGACTGGTCTTGAACTCCTGACCTCAGGTGATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTGCGGGTGTGAGCCACTGTGCCTGGCCTTAAATGACATTCTTGAAATGACAAAATAATAGAAATTAAGAACAGATGAGTGGTTGCCAAGGTTTAGGGAGGTGGAGTCATGAGAAGAGATGGGTTTGGTTATAAAAGGGCGACTCAAGGGATGCTTGTGGTGATAGAAATGTTCTATATCTTGACAGTGGTGGTGGCTACATGAAACTACACATAATGGAATTGCATAGAGCACACAAAAGTGAGCACTTGTAAAACTGGGGAAATCTGTATAAGGTTTACAGATTGCATCCATATCAGCATTCTGGGCTGGGCACGGTGCCTCACACCTGCAATCCCAGCACTTTGGGAGGCTGAGGAGGACAGATTGCTTGAGCTCAGAAGTTTGAGACAAGCCTGGGCAACATGGCAAGACCCAATCTCTACTAAAAATACAAAAATTAGCTGGGCATGGTGGCAAGAGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGTGAGAGGCTCGTTTGAATCTGGGAGGTTGAGGCTGCAGTGAACCGAGATCACACCACTGCACTCCAGCCTGGGTGACACAGCGAGACCCTGTCTCAAAAATAATAATAAAGCCGGGTGCGGTGGCTCATGCTTGTAATCCCAGCACTTTGGGAAGCCGAGGTGGGCGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTAAAACCCCATCTATACTAAAAATACAAGAAATTAGCCAGGCGTGGTGGCGGGCGCCTGTAATCCCAGCTACTTGGGAGTCTGAGGCAGGAGAATCCCTTGAACCTGCGAGGCAGAGGTTGCAGTGAGCCGAGATCTCACCACTGCACTCCAAGAGCAACAAGAGCAAAGCTCTGTCTCAAATAATAATAAATAATAATAATAATTTTTAAAACGTTCTAGTTTTGATATTTCACTGTAGTTTTGCCAGATGTTACCACTGGGGGAACCTGAGTATGGGATACACGGGATTTCTCTGTATTATTTGTTACAATTGCATGTGAATCTGCAATTATTTCAAAATAATGATAATAATTTAAAAGTTTAGTTTAAAAAAATTAACCTGGAGAGCTCGCCCCTTCCTTTGGGTGCCCAGTCCAGGTCCTCCATGCCCTCCATGCCCTCCATGCTCTCCCTCCCTCTCTGTTCTGTAG
Seq C2 exon
GTCACCAGTGATAGTGAACTGGAATCCATGACTGACAAGATGCTGGTGAGAGGGCACGCTTACTCTGTGACTGGCCTTCAGGAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137225:ENST00000398776:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0064816=Peptidase_C2=FE(18.7=100)
A:
NA
C2:
PF0064816=Peptidase_C2=FE(9.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development