HsaINT0028685 @ hg19
Intron Retention
Gene
ENSG00000137944 | CCBL2
Description
cysteine conjugate-beta lyase 2 [Source:HGNC Symbol;Acc:33238]
Coordinates
chr1:89420832-89426970:-
Coord C1 exon
chr1:89426850-89426970
Coord A exon
chr1:89420909-89426849
Coord C2 exon
chr1:89420832-89420908
Length
5941 bp
Sequences
Splice sites
5' ss Seq
TAGGTACCA
5' ss Score
3.96
3' ss Seq
TTTTTTCCTCCTCTGTTTAGCTA
3' ss Score
9.29
Exon sequences
Seq C1 exon
GTGTATAACAGAGAGGAACTGCAAGTAATTGCTGACCTTTGCATCAAATATGACACACTCTGCATCAGCGATGAGGTTTATGAATGGCTTGTATATTCTGGAAATAAGCACTTAAAAATAG
Seq A exon
GTACCAACTATAACACAGAGTCACATATCTAAATGTGTTTGGGCACATATGGAAGAACTGATTGGAAAGCATCCCAGACCAACTCTAAAACAGTCTTTGTAATGGGTATCTGTCTGTATGAACACTTTAAAATAGTATTTAAATGAGCAATACTTTAGTGAATTGATGAATAGTTCAAAGGACAAAGAGTAAGAGATTTTGGATCATACTATAAAGCTATGATACCAGAAAAGTAGTTCTTTTGCCCATATATCCCTGGCTTCTTAGCAGAAATCCAGCAATTACTTGGTACATAAGACACAGGGAGCTTTCTTGTGCCTGAAAAGGTTCTAGACGGTCTATGCTGAACAACTTACCAAAATGCCAAGTCAACAGAAAGAAATTACAGGGGTAGTCAGGTATGCTGCTTGGCCCTTGCTTGAGATTCAGCCATTACTACTGGGCTATCTCATGAATGCCGTACTGTCTGCTGGGGTAGTCCAAACCATGTCAACTATAGGATTACAAACTGGGCTGCAACTTTTGGGTCTTCGCACCTCCCTTTCCTTTGCCTGGAAACACTTTTCCTCCAGGTATCCACCTGACTTCAAATATCCTTCACCTCCTTCAGGCCTTTGTCCAATGTCAGTTTTCATGACCATCACATTGAAAATAGTTAACACCTCTCCCTCCAGCATTTGCTTTGTCCTTTTTCTGTTTTGTTTTGTTTTTTCCTCTATAGTAAATATCAGAATCTATATATTTTACTTCTAAACCACAGTAATGGAGGGATTTTGTTTGTTTTAGTCTCTTCTGCATCCCCATTTTCCATAGAATCTTGTACATGGTAGAGAATTAGAAAGAAATTGTTGAATAAATGAAGATGAAAGATGAAAAGATTAAGAGAAGGATGACTAAAAAATGTGGCAGAGATAGATAAATTTTAAAATTTAGGCCAGGTACAGTGGCTCATGCCTGTAATCCCAGCACTTTGAGAGGCTAAAGTGGGTGGATTGCTAGAGTCCAGGAGTTCAAAACTGGCCTGGGCAACATGGAGAAACCCCGTCTCTACACAGAAATTCAAAAAATCAACCAGGTATGGTGGTCTGTGCCTGTAGTCGCAGCTACTTGGAGGCTGAGGTGGGAGGATCCCTTGAGCCCAGGCACCACTGGCTCACTGCAGCCTCCATCTCCTGGGCTCAAGCAATCCTCCCACCTCAGCCTCCCAAGTAGATGGGACTGCAGGCACAGACCACCATACCCGGCTAATTTTTTTTAAGAAAAATAAAAATAAGAAATGTAATGCACTTATATATTAAATTGTTGCATTGTTGCATGTGCCATAATTATTCCTATAGTATATTACAAGTTGCTATAGAGATGGGAAGAGAAAGCGACTGTTTGAGGGGAATAAAAAAGGAGTGGCCAAAAGATAGAGAATTAGCTAAACAGAGAAATAGAAACTAAACTCCTAAAACATAAACTAGCATGTACTTAGATAAGGAGGTATGAAAGATCAAGATACACTTAAGAAAGGTAAATGATTATTGAAATTTTAAAAACAAAGAAGAAGAAAGGTAAATAAGTTATTTAATTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTTGCCCAGGATGGAGTGCAGTGGTGCGATCTCAGCTCATTGCAACCTCTGCCTCCTGGATTCCAACAATTCTCCTGCCTCAGGCTCCCAAGTAGCTGGGATTACAGGTGCATGCCACCATGCCTGGCTAATTTACTTTTAGTAGAGATGGGGTTTCACCGTGTTGGCCAAGCTGGTCTCAAACTCCTGACCTCGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGTGCCCAGCCTTAATTTTTTTTTTTTTTTAAGAGACAGGGTCTCGCTGTGTCACCCAGGCTGGAGTGCAGTGGCTCAGAGCTCACTGTAATCTCAAACTTTTGCTTTCAAGCAATCCTTCCACCTCAGCCCCCCAAATAGCTATGACTACAAGTCTGCACCCCCTCATCTGGCTAATTTTTTAAAAATTTTTGTAGAGATAGCATCTCACTATGTTGCTCGGACTGTTCTCAATCTCCTAGACTCAAGCGATCCTCCTGCCCTGGCCTCCCAAAGGGCTGTGATTACAGGCATAAGCCATAGAACCTCGCCTCAGTTTGATTTATGAGGGTGTGTTTTAGTAACTGGCATAGATCAGGGTGGAAAACTAGGGTGATTCTAAAGGACTTTGAATATGAGATAGAGTATAAACTTTGTTGAGGAGGTCAGTGGTTCTGAAACTTACTTTAGTGGTAGATCACCATGAGATCACAGTGTTCTACATCATGAAATGGTGATATTGTGAATTCCATCCTGAAAGTAATAGCAATTTTCCTAAAAGAAATCCAACAATTAGAAGCCAATATAAAAATCACACTTCTGTTCATACTTGTCCACAACAAAAAGCTATTGAAATAAACACATTTGAGTTTTTCTGATTTTGCCATTAATATGCATTTACTAAATGCTCATCTGTTTCACTATTGGAGCATCCACTATCAGATAAGTGGTAGTATTTGCTAAAGGCTTAAGAAAATTGTGTGGTAGAAAACTTAACATTGATTTTTTAAAATTCTGCACATTAATTTGATCACCAGAGTGCCAGTGAGCTTACTTTGAGAACTATTGCAAAAGGTGTAACAAAACAGGAGAAATGGTTCCATGACTAGATTTTTTTTTTTTTTTTTTTACAAAGATGAGAGCCAGCCACAGAGGAGGGTCTTAAGCAAATCAGATAACCTAGCAGTGAAGATGGTACATCGGGGCTATTTAGAAACTATAGAGTATAGCATTTGAAGGTGGGAAGAAAACAAGCATGCTACTAAGATCTCTAGCCTGAACTACTCAGCAGTGATGAGACCTTTAACCAGGGTAAATATGGAGAGGAGCAGATTTGTATGGAAGGGCTGAGCAAAGGGAATTCCTGCTTCTCATGCTTTAAACTTGCTGAGTTTGGGTGTCTGTGGGACATAGAAGAATAGATATCTGGGGACAAGTGGAATTATAGGCCTGATCGTCAGAATCAAATTATAATGGGATATATTTTTGGCAGTCATCAAAATGTTGGTGGTAGCTGGACACATGGAAGAGAATGAATTTTCTCAAGGGGAATATATAAACAGAGAAGGCAGCCAGAGATTTGCAGGGTGTGACACCTTAATACACCAAAATGTTATCATGTTTTAAATTGTATCAGAGGCCACAATTGCCCATCTTGTTGGTGACCTCTGTCTCAAGTAATTTGAACTGTTTCCCAGTGGAAAATCAGATTAACATGAACAATTACTTTCTTGTTGTAATTAACTCAGTGTAGCAATATTCATCCCAAAAAATCACTTTAGATCATCTTGAAATTTATTGTTTAGATCTACTCATTTTAAGCCCTTCAGGGTAAAGCATAACTGGTAACATTATTTACTAAAGATATGCAACAGTATTTACTAAAGATATGCAAGATGTATATTTTGAACTTAGATTTTTTTATTTGTAGCAGCCCATAAAGTTTAAATAAGACCAAAAAATGGATACACTATTTCATTATTTAGAAAGTGCAATTTGTTTGCATTAAAACTTAGGTATTCTATCGAATACAATAGTCTTTGTTACATTAAAGATGCAAAATGGCTACAAAATGGCCATTACATCAATTTGCAAAGTGCAACAGTAGTCCTTTAATATATGATGTATCCTTTACTTTAAAGGAAGTGATAATCTGCATTATACGTAGTTTAGATTTTCTCTGATCAAATAGAAAAGTGGGGCATGTGTCATAGTGTTCTTTTGGAGTATTTTGGAAGACCAGAAATGTCTCAGAAGGGATATAATTATTTATATCAAATCTTAAAGTATTCCTTCTTCAAGTGGACATTCTAACTATTTTTCTCATTTATCTTTTTGGGTTTTGTCATATTCCACAGAGAATAAAATTATAACTTTTCTGATTTATATGCTTTTCCTACTGTTTCAAATTTAGCAGGTATTTCAGGGTAGACTGAAATTACTTATACGTTGTTTTGGAAATTTCTGTAGCTGCCTTACATTTTAGTAGGCACTTTACTTGCTTATGAGCAGATTACTTCAAGAAAGCAGAAGCTTAGATTCCCAGAGATGAGCATTTATTTTCCCTTTGTGTGTACCAACACTCTAAGGACAATACAAGAGCCCCCACTTGTGCTTCTGAAAAACAAGTGGAAAAACTTGTGGGTTGCATGGAAAGAACTTCACAAGTAAATTACTTGAGGAATCCACAAAGCAGTATTGTGGGTGGCATTGTCAGAAGAGTGACAGAATGGTAATTTACCAGTTATTACCAATGTCTAGCAAAATTTACAAACTCTTGCATTTTAGACCTCTAGACCTTTGTTACCTGCATTTTCTTAGCCCAAAATATCTTCATTCCCCTTCTCTGCCTGGCTACAGCCTATGTGGTCTTCTATGTCTCAGCTTAAGAATTACTGGCTGCAGAAAGCCACCCTCAACACCCTCTTCTATTCTTGCATCACCCTCCATGCCTCCTACTACAGCATTTATCACACTGCATTACAGTTGTCATTGTATGTGGCTCATGTCCCTACTAGACATTAAATTTTTTGAAGAATTGCATCTTATTCATTTTTGGTTCCTCTAGACCTTAGTCCTTAGCACCTGGTGGTTGCTAATGAATATTTGATGTATGAATGAATCAATGTCTTTATTAAAGATGTTAAACAACTTGAAAACCATTATACAGCCAATTCACATTATTCTTGAGTTCTGTATTTGCAAATTTGCCTACTTCCTAAAATATATGTGTAATTCCAAAATCAATAAAGGGGAAATTTGAGTCACCCTACACACATTCCCAGTCGAGGTCAAACAAGGCAACATTATGCTTCTGTTTCAATTCACACTATAAGCAATTGTTCTCTGTACAGTGATTTTGCTGTTTAAAATGGCCCCCAAGCCTAGTGCTGAAGTGCTGTCTAGTATTCCTAAGTGCAAGAAGGCTGTGATGTTCCTTACGGAGAAAATATGTGTGTTTGATAAGTTTCATTCAGGCACAATGGCCATGAGGATATTAAAGAGTGATAGCTAAAAGGTACAGGGCTTCTTTTGAGATAAAAAAAGTGTTCTGAAATTGGTTATGGTGATAGTTGCACAGATCTATAGATATACTAAAAAAATCACTGAATGGCATACTTTAAATTGGTGAATTTATGGGATTTATATCCCAATAAAGTTGTTAGCAAAACACACGCCCATACACACATACACACACACATGCACACACACACACACATGTGCACACATGATTACTGGGTCCCACTCCCAGAGTTTCTGATTCAGTAGGTCTGGGATGAGGCCCAGTGATTTGCCTTTCTTACAAGTTGCCCAGTGATGCTGATATTGCTAGTGTGAGATCACATTTTAAGAGCCATTGCTCTAGGAAGCCTGGAGAAATACACTCAGAAAATAGGCAAAATAAAGGGGCCTAAACAATAATCAGGATCACAACCTAAGCCCTGCCACTGGCCTATTTTATCGAACCTGCAGTCACTGCTAACATTGAACACTGAATGCTACAGCTCCTGTGACAGCTGCCACTTAAGGCAGTCTGGAACACTGCCTGCTGGTGCCCCTGACACTCCTGCCCCAGAACTAATTTTAAAATTATTAAATCTATTTATATACTATCTTGGTGCAACATTACAGTATTGTAAACTTTTCGTCTGTGTTTTGCATTAAAGTTACATTATCTAAAAAAAAAACTAGAAATAACTATACTGGCTAAATTATAACACACTTATTTTCATTGAATTTATGTATCTTTGTTATGTTTTTAGATTATACTAAATGTGATTAATTGGAAAACAATATTTACCCTTTTTTCCTCCTCTGTTTAG
Seq C2 exon
CTACTTTTCCAGGTATGTGGGAGAGAACAATAACAATAGGAAGTGCTGGAAAGACTTTCAGTGTAACTGGCTGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137944-CCBL2:NM_001008661:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0015516=Aminotran_1_2=PD(19.1=92.7)
A:
NA
C2:
PF0015516=Aminotran_1_2=FE(6.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)