HsaINT0031163 @ hg19
Intron Retention
Gene
ENSG00000117335 | CD46
Description
CD46 molecule, complement regulatory protein [Source:HGNC Symbol;Acc:6953]
Coordinates
chr1:207930885-207933069:+
Coord C1 exon
chr1:207930885-207930987
Coord A exon
chr1:207930988-207932983
Coord C2 exon
chr1:207932984-207933069
Length
1996 bp
Sequences
Splice sites
5' ss Seq
GGGGTAAGT
5' ss Score
9.65
3' ss Seq
CCCTTTCTTTTCTCATTTAGTTA
3' ss Score
9.73
Exon sequences
Seq C1 exon
GAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGGGACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGG
Seq A exon
GTAAGTTGCTCCTTAGAGGAAATAAGGGAAGTGTTAGTAATTTTATTTTTGTTTTGCTTCTCTTCTTAAGCATTCCTGTAAACTTAATTTTGCTTTCTATGTGACAAGTTATACTTCTAGCCAAACAACTCTTGGATGTTTTATGGAGATAGGCAAGATATATAGTAAATAGAAAGTAATTGATATTTAAGGAAAGCAAAACTACTTGCTGTTTCTGACAATAAGTCTGTTGTAAGCATTAAGAATGTAGTAATCATGAGAATTTGTCCTTCACAACTGAGTGTCCCCTATTTAAATCTGCCAACTCTTAGAGTTGAAGTAGGGCTCACAAAAATGAGAAATAGAATTGCCAACTAAAGATACACTTGTATCCAGATGACTCTGTAAAGTGTTATCAGACCAAAACTGACGCGGTTAGCCTTTACCATCATGTTGATCAAAATCTCTCAGTTGAAAAACCTTATTTTTGAGACTGCTACAGTGTGAAGCATCTCAAGAGCAGGTACTGAGCCCTCGGTAATAGCCTTTGTTCTGTAGGGTTTTGAAGTTGTATATATTGGAGATACTAGACATTTAAGATAAATGTGCATTTATAGAGTAAATGTAAGTATTCTGCTATAACAGAATACTTGAGGCTAGGCATTTATAAAGAAAAGAAATGTATTTGGCTCATATTTCTGGAGGCTGGAGAGTTCAAGGGGATGGCAGTAGTGTCTGGCAAGGGCTTTTGTGCTGCATCATAACATGCTGGAAAGTGAAAGGGAAATTTAGCATGTGCAAAAAAGACAAAGCACAAGGGAGGGGGTTCTCGCTTTATAACAACGTGCTCTTATGGTAATGAATCCAAGCCTACAAGAATGAGAACTCATTCCCTGAAGAATTAATGAAGACCCTCTAGAAAGGCATTATACCTCTTAATGACCTAGTCATTTCTTAAAGGCCCCACCACCTCTCAATGCTGTTACACTGGCAATTAAATTTCAATATGAGTTTTGGTAGAGACAAACCAGATTCAAACAATAGCAGTAACACACCATAATATAGAAAAAGTAAGTGAGTCTTGGAGGAAAAATCAGCTGTGACTATGTAAGGCAACTGACAGTTTTTAAAATTTGGTCAAGTAGAAATATTGGAATATTCAGTTGACACATACTGCTTGCTAGGCACACCGAGGGATACCAAAACTTTAAGACAGTGACCTTCCTAAAAGAAGTTCTAACCTTATTGAGAAATAATATATACTGAGAGCAATAAAAGCAAAATACTAAATGAGAAATACCAAATAAGTAGAATTATTCATGATAATTACTCTAAGAGTCCAGAAGGAGGAGAGATTCCTGTGAATTTAAATCAGGGAAGATTTCATTGAGTATAGGGGTATACTTAATGAAAGTATTCTTATACTCAGTGAGCTATTCCTAGAAATACACTCTGTTCTAAATAATATTAATAGAAGCTAAAACTCATGTAGCACTATCTATGTGCCAAATGCTAACTTATCTAATCCCCTAAACAACCCCATGTACTGTTATCCCCTTTTAATCAATTAGGAAGCTGAGTGAAGGAACTTTAAGTGACTTACCCAAGCTCAAGAAACTAGATAAGTTGAGAAGCAGGGACTTGAATCTATCCATTCCAGCTCTAGGGCCTGTTCTCTCTACACAGTCCTTGTCCTTACTGTGCAAAGTGGTGTGAGAAAAGGCACAGAAATGAATGTGTAATGTGATTGCAGGAGGCAGCAAAGAGGCTGGGTGGAAAGGCACAGCAGATTTATTTAGACATCTTTGCTCTTGGCCAATATATATTCAAATGGGGAAACTCTATTTGATTAAATTGCAGATTTATTTAGCACTTTCGTTATATAGTATGTTGTTTAAGAAACCACCCCCTCAAACTACTGTAGTGTAGAAAAGAAACCATATAAAAAATTCCTTCATTATTATGTGTGTCTTATTAATTGCTATACAAAACAGTAACCCTTTCTTTTCTCATTTAG
Seq C2 exon
TTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCAATTTGGAGCGGTAAGCCCCCAATATGTGAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000117335-CD46:NM_172361:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008415=Sushi=PU(52.5=88.6),PF060117=TRP=FE(10.3=100)
A:
NA
C2:
PF0008415=Sushi=PD(45.8=90.0),PF060117=TRP=FE(8.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACATGTCCATATATACGGGATCCT
R:
TCACATATTGGGGGCTTACCG
Band lengths:
182-2178
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)