HsaINT0035190 @ hg38
Intron Retention
Gene
ENSG00000101204 | CHRNA4
Description
cholinergic receptor nicotinic alpha 4 subunit [Source:HGNC Symbol;Acc:HGNC:1958]
Coordinates
chr20:63349653-63356084:-
Coord C1 exon
chr20:63355975-63356084
Coord A exon
chr20:63351028-63355974
Coord C2 exon
chr20:63349653-63351027
Length
4947 bp
Sequences
Splice sites
5' ss Seq
CAAGTGAGT
5' ss Score
9.1
3' ss Seq
TTCGCTCTCTTCCTGCCCAGTGC
3' ss Score
8.55
Exon sequences
Seq C1 exon
GAGTGGCACGACTACAAGCTGCGCTGGGACCCAGCTGACTATGAGAATGTCACCTCCATCCGCATCCCCTCCGAGCTCATCTGGCGGCCGGACATCGTCCTCTACAACAA
Seq A exon
GTGAGTCCTCTACAACAAGTGAGTCCTCTACAGGGCCTTGGTGGGCAGGAGTGGCCAGGGCCTGCCCCTGCCCAGACAGGGAGCTCCACCAAGGCCCAGCCTGGCCCAGCGGGGCCTATGCCAGCCCCATGCATGCCAGCCCAGGCCCAGGAAGGAAGAAGCAGGAGCAATGGAGAAATTGGTGTGGGTTGAGGAGGGAAGGGTCCCCCCAGGCCAGCAAAGAGGCTGAGGGCATCCCTGGGTCTCAGCACTGGAGCGTCAGAGCCGGAGGGGCCTGAGAGTGGCTATGGCACCTGGACACAGTGTCCCTGCCTGGACCAGTCCTGAGGCCTGGGGGCTGGCTCCTGACCCGCGACGTCTTTGCCCCCACCCTTGACAGCTGCAGGAGAGCCCTTTTGGGCAGGAGTGCTTTTCGCCATCAGACCCCATCCTGGCCTTTCTGGGAGAATAGTGTGGACTGCAGGGTGCCCTGGAGAGGGGTGAGGAAGCCCCAGATGGTTCTCATGCCACTAGGGCCTCTGCTTTCTCTGCATACTCACGCTCTGCCCAGGACATGTCACGCCAGGTCCCCAGCAAACAAACAAAGCCTCGGGCTGGGCCAAGCCCATGTCAGGCTCCTAGGAGGCCAAGATGAAGTCTGGTCATGGAAACGGGTTTTCTGTGCCTGGAAGCCAGGGCAGCGTTGCCACGGATTGGCCGTGGCAGATGGTGGCCTCCGGAGGCTGCTGTCCTCTAACTTGTCCTTCCTGCAGATCTGTGCCGAGGGCCCTGCGCCCGGCAGCCAGCGCTCTCTGAGCTGAGTCCTCCAGGGATGATCTCTGGCCACAGGCTCAGGGTCTGGGTGTGGCAGGGTCACAGCTCCCACAAACAAAGCAAATGGAAGCTCTTCCTCCTCTCCCGTCCCAGCCATCTGCCCACAGCCCTTTCCAGGCCCCAGGGCACCCGCCTGACCTACAAACCCTGCTGTATGATTAAGAACGATTGGGCTCCTCTTCCAACTCAATTGATTCCAGTAATGGCAGCGGGAAGGGCCTCCGGCAGTGGGAGGGCCGGACGCTTTTCCAGAGTGCATTGGGGAGGTGGTCAGTGGTGAGTGGGCAGCGGGTGGTCTTCCCTTAGGACAGACTCCCTGCCCCCTGCAAGCCACCCAGCCACCTAGCTCCCCGCCACCAGGACCATGCACCGAATCCGCCTGTGTGACTCGCATGGACACATTTCAGGGAGAAGTGGAAACGCCCAGGATGGGCCGGGCAGAGAAGCCGCTCTGGGTGCCTGTGCACAGCCCTCCAGGAATGCAGCCCCCAGGAACGAAGCCTCTGAGGACCACAGCCCCCACTGTGACCTCAAACCCCCAGGACCACAGCCCCCCGAGTACTGCAGCCCCCCCCACTTCCACAGCCTCACCAGGACCACGGCCCTCCAAAGACTGCAGCCCCCACCAGGTTCACAGCTCCCCCAGGACCACAGTTCCTCTAGGACCACAGCCCCCTAGGACCACAGGCCCCCAGGACCACATTCCCTGCCAGGACCACAGTCCTCCCAGGACTTCATCCCACCCTAGGGCTACAGTGCCTCCTGCAGAACTGCAGCCCCCACAAGGATCACAGTTCTTGCCTGACCACAGCCCCCTAGGACTACAACACCCCTAGGACAGCAGCTCCCCCCCAGGACCACAGCCCCCTAGGACCACAGCCCCCCAGGACTACAGCCCCCCAGGACCACAGCCCCATTTAGGACCACAGCCCCCTAGGACCACAGCCCCCCAGGACCACAGCCCCCCCAGGACCACAGCCCCCCAGGACCACAGGCCCCCAGGACCACATTCCCTGCCAGGACCACAGTCCTCCCAGGACTTCATCCCACCCTAGGGCTACAGTGCCTCCTGCAGAACTGCAGCCCCCACAAGGATCACAGTTCTTGCCTGACCACAGCCCCCTAGGACTACAACACCCCTAGGACCGCAGCCCCCCCGCCAGGACCACAGCCCCCCAGGACCACAGACCTCCCAGGACCGCAGCCCCCCCGAGGGTCACAGCCCCCTAGGACCACAGCCCCCCAGGACCACAGCCCCCCAGGACCACAGCCCGCTAGGACCACAGTCCCCCCAGAACCACAGCCCCCCCGAGGGTCACAGCCCCCTAGAACCACAGCCCCTCCAGGACCACAGCCCCCTCTAGGACCATAGCCCCCTAGGACCGCAGCCCCCTAGGACTACAGCCCCCCAGGACCACAGCCTCCTAGGACCACAGCCCCCCCAGGACCGCAGCCCCCCCAGGACCACAGCCTCCTAGGACTGCAGCCCTCCCAGGACCACAGCCCCCTAGGACTACAGCCCCTCCAGGACCACAGCCCCCTCTAGGACCACAGCCCCCTAGGACTGCAGTCCCCCCAGGACCGCAGCCCCCCCAGGACCACAGCCCCTCCAGGACCATGGCCCCCTCTAGGACCACAGCCCCCCAGGACCGCAGCCCCCCCTAGGACCACAGCCCCCCCAGGACCACAGCCCCCCTAGGACCACAGCCCCCTAGGACCACAGCTCAGGAGAGCAGGGATTGCTGCCACCCCATGTTCTCCTGTGTCTCCTCCTCACCATGGCCTGTGGGATGTAGTGGGGTGACCCCAGTTTTCTCTTTGGGGCTGGGATTGTCACCGAGGCTCTCTCCGGACAGGACCCAGGGTTCCTGGAGTGGCCGCTGGTGCTGGGTCTGCTCCCGCTGAGGAGGCCTGTTTCTGGGGCAGCAGGTGGCTGTGGCTGGTGGCCGGCCAGGCTGCAGGGTGGGAGGCCTCGGCCCTTCTCTGGGATTTGGCCACCCCCAGTTGGGGGCCCTGCTGTCCACTTGGGGCAGGTGCCCAGAAATCCCTGACCTGGACTGGGGTCGGGGTGGAGGGGACAGAGGGTCTCACGCCAGCCTGTGGGCCCTGGAGCAGGAACCTGGACCTGCTGGACTGGGCGGCTCCTCAGACCCTGTCTGCTCCCAGGGTGCAGCTTTATGGTGCGAGTCCAGAGCCGGCTCACGGCCGGGTGGTTCAGCCCAAACGGGGTTCTCCTCAAAGGCTCCCCAGAGGGCGGCTGGAGCCAGGGGTGGGCGGGGCAGGGAGCAGCAGTGATGCAGCCCAGGGGTGCTGTGGGACCTGGGGGCTGGGGGACCTGGCCCTGACCTTGTCCCGTTTCCTGTGGCGCGGGCAGAGGACCCTGGGGGAGGGGGGCCCTGCCCAGAGTGGCGCAGACCTGCACTGTTCCCTGAGCATGGCCCTGGCGTTCCCTGTAGAGTGTGTGCTGAACAGAGTAGTCACCCGCTTGCCATATGAGAATCTTTTAATTTGTGCCTCAGAAGGTGGAGGGCGTTGGTTTTTGGAGAGATGGGCTGGGGAGAGGGAGCAAACTTGAGCCTGATTCCACCCAGACTGACTTGGTGGTAAAGCCCCGCCCCCCGCTGGAGGGACGCTCGGGAGCCAGGCTGTGCTGGGCCGGAGCCGCATTGAGATGCAGCTGGTGGCTCTTGCTGGGTCTCCCTCCCTCTGCAGCTGAGCGGCAGCCCAGCCGGCGGTGTTGGCTCAGGACCAGTTCAGGGGGGCAGAGGCTCAGCACCGACTGAGACCGTGGGGGGCCAGGTCTCCACGACCTGGAGGGCAGAGCTCCAGCAGTGGCGGCTCCACAAAGGGAGGGTCCCTGAGGGTTGGGAGGGAGGTTGAGGTGCAGGTCCAGCCCTGGGACTCGGGGGCAGGCACAGAGGAAGCTCAGGGAACAGTCGCCAGCTCTGCCCAAGTACCTGGAGAGGCCCTGGCCTTTGAGCAGGCTCTCAGGGAATGAGGCAGAGGAGGGATGGGCAGGGGTCCAGGCAGCTTGGCAGAGGTGGAGCAGGAGGTGTGTGGCTGGGCAGCCGCTCCCCCCGACGCGTCGTGCCCCAGCGCCCTCCACAGAGCTGAGCCTGGCCCCATGCCTGCCAACGCTGGGGATTTAATGGGGCCTCAGGCTTCCCATTGGTGGGGACTTCTGTGGGTGGGGGTGGAGGGTCGGCTGCTGCCCCCGTGAGCCTGGCTGCCTCAGCCCTGAATGTGCTCCTGCAGTGCGTCCCACCCAGCCAGCCGCTGTCTATGGAACCAGGGGCTGGGGCTGGGAGCTCTGCCTACCGGGAGGAGTTCAAGGGACATCAGCCCCTCGCTCCATTGCTCTGTTGCCCACCTGGGCCTGTGGACAGAACACCCACGTCCCCCAAGGCAAAAGAGAGTCCAGAGCCAGTGGCTCAGACGTGGCCCTGGAACTGGGCAGTGCGTATGCAGCCCCACTGCATTGGCCCTGGGTGGCCAGAACACCTGTCCTTGCCTCTGTGGCCCCTGGTGTCCTCATGCTCACACACTGGGAGGTGGCCTCCAAGTCCTTGGGGTTAACGGCAGAAGCTGGGTGAGGAATTCCCATGGTGGCCCGGGGTGCTGCTTGGAGGGGCGGGGACATAGGGATGCCGTGTGTCCCAGGAGGTGACGCTGGGAGACTAGCCCCATCCATGCGCCACTCATGGATAAGGGTAATCACCAGCAGCAGTGATTATGTGTGTCAGGCACTCGTAGGTCCCTTCCCGTTCTCTGAACCACGTGCTACGCCCAGCTCAGGGATGATAAACTGAGGTGCACGAGTAGGTGAGAAGACGAACAGTGTACCCGGGCAAGGCCGCCAGCCCTTTTGTGCTCCTGTGACGTGAGAATGCCTCTGTGTGTGGACGTGGACGTGGACGTGGACGTGGGTGTGGATGTGGGCGTGGACGTGGACGTGGGTGTGGATGTGGGCGTGGGACATGGATGTGGGCGTGGACGTGGATGTGGGCGTGGACGTGGATGTGGGCGTGGATGTGGGTGTGGGTGTGGACGTGGGCATGGGTGTGGCAGTGGGCGTGGGTGTGGACGTGGGCATGGATGTGGGGGTCTCACACCCTTCGCTCTCTTCCTGCCCAG
Seq C2 exon
TGCTGACGGGGACTTCGCGGTCACCCACCTGACCAAGGCCCACCTGTTCCATGACGGGCGGGTGCAGTGGACTCCCCCGGCCATTTACAAGAGCTCCTGCAGCATCGACGTCACCTTCTTCCCCTTCGACCAGCAGAACTGCACCATGAAATTCGGCTCCTGGACCTACGACAAGGCCAAGATCGACCTGGTGAACATGCACAGCCGCGTGGACCAGCTGGACTTCTGGGAGAGTGGCGAGTGGGTCATCGTGGATGCCGTGGGCACCTACAACACCAGGAAGTACGAGTGCTGTGCCGAGATCTACCCGGACATCACCTATGCCTTCGTCATCCGGCGGCTGCCGCTCTTCTACACCATCAACCTCATCATCCCCTGCCTGCTCATCTCCTGCCTCACCGTGCTGGTCTTCTACCTGCCCTCCGAGTGTGGCGAGAAGATCACGCTGTGCATCTCCGTGCTGCTGTCGCTCACCGTCTTCCTGCTGCTCATCACCGAGATCATCCCGTCCACCTCACTGGTCATCCCACTCATCGGCGAGTACCTGCTGTTCACCATGATCTTCGTCACCCTGTCCATCGTCATCACGGTCTTCGTGCTCAACGTGCACCACCGCTCGCCACGCACGCACACCATGCCCACCTGGGTACGCAGGGTCTTCCTGGACATCGTGCCACGCCTGCTCCTCATGAAGCGGCCGTCCGTGGTCAAGGACAATTGCCGGCGGCTCATCGAGTCCATGCATAAGATGGCCAGTGCCCCGCGCTTCTGGCCCGAGCCAGAAGGGGAGCCCCCTGCCACGAGCGGCACCCAGAGCCTGCACCCGCCCTCACCGTCCTTCTGTGTCCCCCTGGATGTGCCGGCTGAGCCTGGGCCTTCCTGCAAGTCACCCTCCGACCAGCTCCCTCCTCAGCAGCCCCTGGAAGCTGAGAAAGCCAGCCCCCACCCCTCGCCTGGACCCTGCCGCCCGCCCCACGGCACCCAGGCACCAGGGCTGGCCAAAGCCAGGTCCCTCAGCGTCCAGCACATGTCCAGCCCTGGCGAAGCGGTGGAAGGCGGCGTCCGGTGCCGGTCTCGGAGCATCCAGTACTGTGTTCCCCGAGACGATGCCGCCCCCGAGGCAGATGGCCAGGCTGCCGGCGCCCTGGCCTCTCGCAACACCCACTCGGCTGAGCTCCCACCCCCAGACCAGCCCTCTCCGTGCAAATGCACATGCAAGAAGGAGCCCTCTTCGGTGTCCCCGAGCGCCACGGTCAAGACCCGCAGCACCAAAGCGCCGCCCCCGCACCTGCCCCTGTCGCCGGCCCTGACCCGGGCGGTGGAGGGCGTCCAGTACATTGCAGACCACCTGAAGGCCGAAGACACAGACTTCTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000101204:ENST00000370263:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.196 A=NA C2=0.348
Domain overlap (PFAM):
C1:
PF0293118=Neur_chan_LBD=FE(17.4=100)
A:
NA
C2:
PF0293118=Neur_chan_LBD=PD(55.6=25.1),PF0293211=Neur_chan_memb=PU(91.1=73.2)
Main Inclusion Isoform:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development