HsaINT0037722 @ hg19
Intron Retention
Gene
ENSG00000188986 | COBRA1
Description
cofactor of BRCA1 [Source:HGNC Symbol;Acc:24324]
Coordinates
chr9:140150781-140151506:+
Coord C1 exon
chr9:140150781-140150880
Coord A exon
chr9:140150881-140151275
Coord C2 exon
chr9:140151276-140151506
Length
395 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGGG
5' ss Score
8.76
3' ss Seq
CAGCCTGTGGTGTCATGTAGGTT
3' ss Score
5.89
Exon sequences
Seq C1 exon
GTACAAGAAGCTGGAAGACCTTCTGGAGAAGAGCTTTTCTCTGGTGAAGATGCCGTCCCTGCAGCCCGTGGTGATGTGCGTCATGAAGCACCTGCCCAAG
Seq A exon
GTAGGGCCCTAACCCTAACCCTGATGGCGTGGACCGTCCGCCCACTCTCATGCCCTTGGTTAGTGGAAGTTCCGGTGGCCGCCTAGCTCCGGGAGCTTCCTGTGCTGCCTGCCCAAGTGCTGTCCATGGTGAGCTCTGTGCTGACTTCTCCCACATGAGCCGCGTGGAGACCGAACCTTAGCACTGGAGTTAGGGTGTGGGGCCCCTCCTGGGAAAGAGCTGTTGGTATTTAGCATGTCTGTCTGACATGCTGGGGCCGGGGAACCAGTCATAGGTGCCCTGTGGGGTGGAGCTTAGCTCGAGGTGGTCTCTGCGGGGCTGAGGCCTCTTGGCTTGTCTTGAAGGAGACCCAGGGACACAGGTGCCACTCACAGGCAGCCTGTGGTGTCATGTAG
Seq C2 exon
GTTCCGGAGAAAAAACTGAAGCTGGTTATGGCTGACAAGGAGCTGTATCGAGCCTGCGCCGTGGAGGTGAAGCGGCAGATCTGGCAAGACAACCAGGCCCTCTTCGGGGACGAGGTTTCCCCACTCCTGAAGCAGTACATCCTGGAGAAGGAGAGCGCTCTCTTCAGTACAGAGCTCTCTGTCCTGCACAACTTTTTCAGTCCTTCCCCCAAGACCAGGCGCCAGGGCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188986-COBRA1:NM_015456:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF062098=COBRA1=PU(3.4=47.1)
A:
NA
C2:
PF062098=COBRA1=FE(16.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTACAAGAAGCTGGAAGACCT
R:
CTGGTCTTGGGGGAAGGACTG
Band lengths:
318-713
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)