HsaINT0037727 @ hg38
Intron Retention
Gene
ENSG00000188986 | NELFB
Description
negative elongation factor complex member B [Source:HGNC Symbol;Acc:HGNC:24324]
Coordinates
chr9:137266331-137267086:+
Coord C1 exon
chr9:137266331-137266426
Coord A exon
chr9:137266427-137266943
Coord C2 exon
chr9:137266944-137267086
Length
517 bp
Sequences
Splice sites
5' ss Seq
ATGGTAACG
5' ss Score
6.05
3' ss Seq
ATGGCCTCCCCTCCTCGTAGGAG
3' ss Score
8.78
Exon sequences
Seq C1 exon
GACAGCCCCGACCTCCTGCTGCTGCTCCGGCTGCTGGCGCTGGGCCAGGGAGCCTGGGACATGATCGACAGCCAGGTCTTCAAGGAGCCCAAGATG
Seq A exon
GTAACGAGCCTCCTGTGGGGGCTGCCAGTTTCCTACGAGGGGTTGTGGGCTGGAAGTGGGGTGGAGGGGGAGGCGCTAGCAAGGTGATTGTGGAGGCCCCTTTGGTCCCAAAGCTTCCTTCCTGGAGCTGCCCACCTTCCTTTTGGGAAAATGCCCACCAGGGAGGTTCTGGGGTGTCTCCGTGGACCCTGGCTGGTTCTGGGGTATCTCCATGGCCCGTGGCTGGTTCTGGGGTGTCTCCGTGGACCGTGGCTTGTTCTGGGGGTGTCTCCATGGACCATGGCTGGCCACAGGTGGTGACTACTCCATGTGGGTCCAGACCTAGAAGGGGGTTTGAGGAGATGGCCTGGGTGGGGGACTCGGGAGGTGGGAAGAGGGACCTGGGGACCTGGAGAGGAGGGAGGGTCGGTGAGGTATCTGGGGGAGTGGGAGGGCCAGGGGCAGGGTGTGTGTCACGTCAGGGTGGGGTGGGGCAGGGCCCGGGCCCGCGCCCGCTCATGGCCTCCCCTCCTCGTAG
Seq C2 exon
GAGGTAGAGCTCATCACCAGGTTCCTCCCGATGCTCATGTCCTTCCTGGTGGATGACTACACTTTCAATGTGGATCAGAAACTTCCGGCTGAGGAGAAAGCCCCAGTCTCATATCCAAACACACTTCCCGAAAGCTTCACTAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188986:ENST00000343053:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.035
Domain overlap (PFAM):
C1:
PF062098=COBRA1=FE(6.5=100)
A:
NA
C2:
PF062098=COBRA1=FE(12.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACAGCCCCGACCTCCTG
R:
TAGTGAAGCTTTCGGGAAGTGTG
Band lengths:
238-755
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development