HsaINT0046718 @ hg19
Intron Retention
Gene
ENSG00000205744 | DENND1C
Description
DENN/MADD domain containing 1C [Source:HGNC Symbol;Acc:26225]
Coordinates
chr19:6475495-6475762:-
Coord C1 exon
chr19:6475717-6475762
Coord A exon
chr19:6475597-6475716
Coord C2 exon
chr19:6475495-6475596
Length
120 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGC
5' ss Score
8.7
3' ss Seq
CCGACCCCGCTTTTCCGCAGAGA
3' ss Score
8.14
Exon sequences
Seq C1 exon
CGCGCCCATGCCCTACCTCATTGGAGTGCACGCCAGTCTCGCCGAG
Seq A exon
GTGAGCGTGGATCTACCCAGACGACGGGGACGTGAGGGTTCCCCCTTCCTCTACATCCCCAGATGCCCTCCTCTGCCAAGGACTCCCGGGCTCTGAGCGGCCGACCCCGCTTTTCCGCAG
Seq C2 exon
AGAGTACGAGAAAAAGCCCTGGAGGACGTCGTGGTGCTGAACGTGGACGCCAATACCTTGGAGACGACCTTTAACGACGTGCAGGCGCTGCCTCCAGACGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000205744-DENND1C:NM_024898:12
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0214116=DENN=FE(7.4=100)
A:
NA
C2:
PF0214116=DENN=PD(8.3=50.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCCATGCCCTACCTCATTG
R:
CGCCTGCACGTCGTTAAAGG
Band lengths:
130-250
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)