HsaINT0048787 @ hg19
Intron Retention
Gene
ENSG00000187908 | DMBT1
Description
deleted in malignant brain tumors 1 [Source:HGNC Symbol;Acc:2926]
Coordinates
chr10:124392707-124395715:+
Coord C1 exon
chr10:124392707-124392857
Coord A exon
chr10:124392858-124395506
Coord C2 exon
chr10:124395507-124395715
Length
2649 bp
Sequences
Splice sites
5' ss Seq
CCAGTAAGT
5' ss Score
9.09
3' ss Seq
GGTGTGTCCTCTCTCTGCAGGCT
3' ss Score
11.04
Exon sequences
Seq C1 exon
CAGATTATTCCTGCGGAGGCTTCCTATCCCAACCATCAGGGGACTTTTCCAGCCCATTCTATCCCGGGAACTATCCAAACAATGCCAAGTGTGTGTGGGACATTGAGGTGCAAAACAACTACCGTGTGACTGTGATCTTCAGAGATGTCCA
Seq A exon
GTAAGTGTGCGCCCAGAAGAATGCCTTGGGGCCCCACAGACCTTTCAAGAGGGAATAAATGGTGCTTAAGTGTGCGCCCAGAAGAATGCCTTGGGGCCCCACAGACCTTTCAAGAGGGAATAAATGGTGCTTAGAAAGCCAGGAGAGAAGTTTGCTGAGAGACATTTTTGACCTAGCCCAGAGGCATCCCGTGGAGAGTTGGGGAGGGGGCACGAGAGCCTTGGAGTGGACAAAAGCTCTGGTTTCAAGTCCTAGGTCTTTCACCAATTTGCTGTGTGACCACAGGAAGTCACTCAACTTTCCTGAGCCTCAGTCAAAAGAGGGGAATAAAATACCTGCTTTCCTCACCTCACTGTTTACTGGGAAGGTCACGAGAAACAGAGAGGAGAGAGAGGGAGAGAGATGTGAAAATATTTACAAAATGTTGTCCAGTGGAAAAGATGGTTGTTAAGTAGTAATGATAGACTTAGGGGCAATAATAGCACTAATAATCCTATTAACAACCACACTGGCCAGGTATGCTGCCTCAGGGTTGTAATCCCAACACTTTGGGAGGCCGAGGCAGGAGGATCACCTGAATGCAGGAGTTCAAGACCAGCCTGAGCAATATAGGGAGACCCCCCATCTCTACAAAAAAGTACAAAAATTAGCTGGGTGTGGTGGCCTGCACCTGTAGTCCCAGCTACTAAGGAGGCTGAGGTGGGAGAATCGCTAGAGCCCTGGGAGTTGAAGGTTGTGGTGAACTATGATAGCGCCAGTGCACTCCAGCTTGTGGAACAAAACGAGACCCTGTCTCAGGAAAACAAAACAAAACAAAAAGAACAATTGTATCTGTTTTGTGGAACCCTTTTTCTCCACCCATTCCTTTCTTCATGTGAGTTCCCCAGGGGTCGGGCAGAGATGGAGGAATTGCTGCTCCAGAGGGTAGGGTATCTGCTCTGCATCCAATCATAAGTAGAAATCATCGTTTTAAGCAGAGAGGACATTACTAAAAGCACTTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTTCTTTCTTTCTCTCTCTCTCTCTCTCTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTTTCTCTCTTTTTCTTTCTTTCTTTTTTTTTCCGGACATGGAGTCTCGCTCTGTCACCCAGGCTGGAATGTAGTGGCACGGTCTCGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTTTCAAGTAGCTGGGCTTACAGGCACACGCCACAATGCCTGGCTAATTTTTGTATTTTTATTAGAGACGGGGTTTCACCATATTGGTCAGGCTGGTCTTCAACTCCTGGCCTCAGGTTATCCTCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCATGCCTGATGTCAAAAGTACATTAATATATGATTTATCCAAGGAGGCGGGTGGCCCAGCTAACTGTGAAGAGGCACCAGTGTTTGCTAGTGTCCTGAACAAGGGGCTACACTAATTTCTTCTCTAACAGCCACTGTTGAACAAAATAGTTTTCCCTGTTGATTTCTGTTTGCAGTGGGCTTTGGAGTCTCTGCTTTAGTGATTCATTTGGGATTTTGCAAAAGATACATCATTTTATTCTCTTTGTCATTACAATACAAAGATTGCACTTAAAGCTGATGCAGTCCTATGGGAAAAGGTTGACCATGACTGGTTCTTTAACCAGCATCTTGATAGCAATGACCATCACCATTTGTGACATTTTACAAAGCCCTTTTCTGTATGTTGTTTTATTTGAGCTTCACCATAGCCCTCTTCAGTGTGCATGGATCAGATTACTTTGCCTTTGTAAATAGGAAAAGCTTTAGAGAGATTATTTGACTTGCCCAGTATTTATTTATTCAATTATTTATTTCTCTCACTATGAATTCATGCATATTGATTTTATTCTGTGGGGGCACTAGGGACTTTTCGATGGAAGAAAAATGGTCTAAATCAGGATGCGAGCCCTTCCTTTCCTGATGTAAAGGGCTGACAGGTGAGGGGCTGTAGATTTCATATGTGTGATTGCAAAGGGCAGGACTAAGACCCAGGCATGGAGGTTGAGGGAAGATGAGACTCTCTTGATTTAAGGATACCTATGACTTTCTTTTGTTTCAATTTTTATTTTTCTTTTTATTTTTTGAGACAGGGCCTCACTCTGTCGCCCAAACTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAACCTCTGCCTCCTTGGTTCAAGTGATTTTCCTGCCTCAGCCTCCTGAGTAGCCTCCCTCACCCTACAGGCTTGTGCCACCACGCCCGGCTAATTTTTGGATTTTTAGTAGAGACAGGGTTTCACCACGTTGGCCAGGCTGGTCTCGAACTTATGACCTCAGATGATCCACCTGCCTTGGTCTCCCAAAGTGCTGGGATTATAAGTGTGAGCTACTGCGCCCAGCCAAGGAGACCTATGACTTTCATCGATGAACTTTGTCAGAGTTTCTGGCACAGAGGTGTGACCCCACCCTGAGATCTGACCCCCTGCGTCAAATTCTGGGAGGAAATGAAGCCAAATGGTGTGTCCTCTCTCTGCAG
Seq C2 exon
GCTTGAAGGTGGCTGCAACTATGATTATATTGAAGTTTTCGATGGCCCCTACCGCAGTTCCCCTCTCATTGCTCGAGTTTGTGATGGGGCCAGAGGCTCCTTCACTTCTTCCTCCAACTTCATGTCCATTCGCTTCATCAGTGACCACAGCATCACAAGGAGAGGGTTCCGGGCTGAGTACTACTCCAGTCCCTCCAATGACAGCACCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000187908-DMBT1:NM_004406:36
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0043115=CUB=PU(43.0=90.2)
A:
NA
C2:
PF0043115=CUB=PD(56.1=84.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)