HsaINT0059106 @ hg38
Intron Retention
Gene
ENSG00000088926 | F11
Description
coagulation factor XI [Source:HGNC Symbol;Acc:HGNC:3529]
Coordinates
chr4:186274116-186275896:+
Coord C1 exon
chr4:186274116-186274275
Coord A exon
chr4:186274276-186275786
Coord C2 exon
chr4:186275787-186275896
Length
1511 bp
Sequences
Splice sites
5' ss Seq
TCGGTGAGT
5' ss Score
11.11
3' ss Seq
TCCTTTTTCTTTTTATTCAGTAA
3' ss Score
8.05
Exon sequences
Seq C1 exon
CTTGCAACAAAGACATTTATGTGGACCTAGACATGAAGGGCATAAACTATAACAGCTCAGTTGCCAAGAGTGCTCAAGAATGCCAAGAAAGATGCACGGATGACGTCCACTGCCACTTTTTCACGTACGCCACAAGGCAGTTTCCCAGCCTGGAGCATCG
Seq A exon
GTGAGTGAGTCCCAGGACATTCGAGTGGTCGATGAAAAACAGAATCGTGATTTACTAAAAAGCTTTTGCCATCAACTTTATGCCAGAATTTATTTTGAACCCCTAAAAGACATTTCTATAATAGTACTCCTAGTTTTCTTCATGAAAAATACACTTAAAGCCTAATTTGGATGCATTTCATTTATGGTAAGGAGTCTATCTTTTAATAACACTGTCAGAAAAATATATATACTTGGCTAATTTCAAAAGCGCTACACTTTTAAATTGGCACTTTTGAAACAGCTGCAATTGGTATGATTGTCAGTGCCCTTCCCAGTCTAAAAAATGTTACAGTCTAACAGAATAAAAATAAAAACCTACTCTCTCTCTCTCTAAATAACAGTTCCTTACCTAAGACAAAATACTCATGTAAAAAGTCTTATCCTGCTCCATACTGGATTTTGAAATATTTCAAGGATAAATCTATCACATAAGGATTTAAAAATTATCTGATCTCTAATAACCAAATCTGTGTTCTCATCTTTAAAAATTTACTAGGGAAATAGATTATTAATTTGTATATTCAGAAATATTTGAGATGATTTAGATTTTCATAGTAAACTGCATTTATCTGGAATCAACAGAAAAGTGAAAAACATTCAAATTACTAATACTTGCGTTTTAACATTGGATTTTAACATTCTGCTCTCCACATTCACAAAGAGGAGTGAACAGAAAGCAAACAAAGCATCAACGAGTTATTTCAAAAACAACAGTGGTGAAAAACACACACACCAAACCCCTAAATTCATGATTTGACTTGTAAGGCTTATCTTTAGCTCAGCTCAGACGACAGCTTTTATGTCTAAGACTTAACAGAATGTGAACTGCAAGACAAGAAATTGGAGGTTTCTAAGCAAGATAAAGTTAAGTCATTAAAAGTAAGAAGGACTTAGCCAGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACCTGAGGTCAGGAGTTCGACACCAGCCTGACCAATATGGTGAAACCCCGTCTCTACTAAAAAAGAATACAAAAATTAGCCAGGCGCGGTGGTGGGCGCTTGTAATCCCAGCTACTTGGGAGGCTGAGACAAGAGAATCGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCAAGATCGTGCCATTGCACTCCAACCTGGGCAACAGAGTGAGACTCCGTCTCAAATAAAAAAAAACAAAAAATGAGAAGGGCTTGAGAAGTCATTCATTCATGCACTCTCCTTCTTCATGTGGTCACTCTCTCAAGCTGTCATTATACTGAAGAAGAAATAAACTTACACAATTCACAGGTGCTTAGCAACACTGCTGGGACCATGCCCAGCCATTCAGCCTCCCAGATGGATGCTTCGGGGTCTCGCAGGTCCTCTCTCCAAAGGGGACTTTCTTAATATCTCATGTTTTTTCCTCCTTGCAGTTGGAAGAATAAGACACTTTTCCTTTTTCTTTTTATTCAG
Seq C2 exon
TAACATTTGTCTACTGAAGCACACCCAAACAGGGACACCAACCAGAATAACGAAGCTCGATAAAGTGGTGTCTGGATTTTCACTGAAATCCTGTGCACTTTCTAATCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000088926:ENST00000403665:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0002421=PAN_1=PU(61.9=96.3)
A:
NA
C2:
PF0002421=PAN_1=PD(36.9=81.6)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTGCAACAAAGACATTTATGTGGAC
R:
CCAGATTAGAAAGTGCACAGGA
Band lengths:
270-1781
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development