HsaINT0061951 @ hg19
Intron Retention
Gene
ENSG00000078098 | FAP
Description
fibroblast activation protein, alpha [Source:HGNC Symbol;Acc:3590]
Coordinates
chr2:163051211-163055391:-
Coord C1 exon
chr2:163055267-163055391
Coord A exon
chr2:163051259-163055266
Coord C2 exon
chr2:163051211-163051258
Length
4008 bp
Sequences
Splice sites
5' ss Seq
ACGGTAGGT
5' ss Score
10.15
3' ss Seq
TGTTTTCATCCTGCCCACAGGCC
3' ss Score
11.69
Exon sequences
Seq C1 exon
AATTAGCATTGGAAGCTATCCTCCAAGCAAGAAGTGTGTTACTTGCCATCTAAGGAAAGAAAGGTGCCAATATTACACAGCAAGTTTCAGCGACTACGCCAAGTACTATGCACTTGTCTGCTACG
Seq A exon
GTAGGTAACGGACCTCACATAAGCACAGCATCCCCACAGGCATGGTTGTCATCCTCCTCACCTCTATCTGATCAATTCGTAGCTACAGTTAATGAGCATTTGTTATATGTAAGAATCTTATCTTGTGCTTATAGAAAAAAAATTAAAGGAGGATAGGAAGGTATTATTATCTTTACTTTTTTGCAACTGAGGAAACAGAGTTTGGGGAAACAGGGTAACTTGCCAAAAGGTCCGCACTGCAGCTAAGCATCAGCCAGGACTGAAGCAAGTGCTGTTGCCTCTAAGTCCCATGCTCTTAACCACCACATTCCACAGCACTAAGACTGCGTGCAGAGGCAACCCGTCAGCTAGGCTTCGCAAGACCTGAGCAATCGCAGAAAAAGAAATGTTCTCTGATAAAATGGTTGCTGGACTTTTGGCCCCCTTTGCCCAGAGAAATATCAAACTCTCACATCCAGGGGAATGAACAACGGCTTGGAAACCCGAGATGCCCACGTCGGAGGTCAATCATTCCTCAAACTGTAGTTTCAATGGGGATAGAAGATGAACCTTTGTCCTTTCTAAATTTGGAAAACATCGTAAGTAATGCATCAAATATAACAAACCATAAGTAATAAAATCTACAAAACATTTCCTGGTTGTTTAGGACATACGTACATTTAATGAATAATTTCTACCCATATAATTTTATTTTATGTGCAACCTTTTATCTATATCTTGAGCATGTGGCAAACAATAAAACAGGTTAGGTTAAGAGGCCAATATAGATCAATGAAATATATTGGGGTCTAAGTAGTCATTATGGAGATTTGGAAAACTGACTCGGGAATCTCTAATTCTCCAATCTCTGTCACCTCCCTCCAGCTTATTCCTAATTTGGGGCTGAGAGTTAGAGTACTTGGAAAAAGGTATTACAAAATGTATGCTACCCTCCTGTTTTGGTATCAGCTCCCCTGGTAGGGGTATGTGGCTTAAAGAACAAATGGAATCTTTGACTGCTTGATATCCCTATTCAGTTGCAGAGGCCCTGAAGATCTCATAAAGGGAACCAGAATGAAGGCTACCCTAACATGCCACTTCCCTCAGTCCAGCCACCTGGCCCCGGAACCTGAGCTGCAGCTCATTTGACTACGTGGACATGAATAAGCATTTTAACCCAAATTCTCCCTTGAAGATAGCACAAAGATGTCAGTTTGAAATAACACTTTCATAAAATGTTTGGTCAATGGCATCTTTGAAATGTCAAGAGATTGTTGTTCATGACCATATGTGCTGATTGTGGTTACTGGCATTTAAAGGTATACATTAAATGTCCCTCTCAAGTTATATGCAACATTTTTCAACCTAAGCTATATATTTATGCAACATAGATTGAAAGCTTACATGCCAGGCACATAGTATCATTGAGCTAACTATACTGAGTCATCTGTTTATCTATCTTTTTCTCCTGGAAGGCAGGGGCTACATTCTTTTAATCTTTGTATTTCTAAGACCAAGAAGAATGTCTAATACATAATAGACATTCAATGTTTGTGGAATTAACATAGATATGAGGTAACATTGCTGTCCCTTGCAGTCTACCAAAAAAGCTGGTTTTATGCTGATGCATTTGCTGATGAATGCATCAGTGACACTACATTTACATCCATGCATTTATATATGTATGCATTCTGCATTTGTATAATGCTTTAATGTTTTTGGAAGGCACTATCTCACATTTTGTATTACGTTGTCTTCCTAATATCTACTTGAGCCTGTGTGCCCACTGAAGAGATGAAGAATAAAAGCCTAAGCTCTCATCAAAAGTTGGTGGAAGAGTCCTTTCTAGAACTTGAATCGCCTGACTTTTCCACCACTCACTCTTCCTCGGCAGTATGGTAATTTCCCATTTAGCAAAAAATATACTGTGTGGGAAGCATCACATCGTCTGGTGTTTTTGAAGCTCCAGTAAAATGAGTCACTGCGCCATCATAGGAAAAACCTTGAAATCTTTCCCTTCAGGACTAAGAGTAAAGCCTCATTATGTAACTTCAAACTCTCCCGAGGGATGGTTAGTAAGTCCCAGATGATAGGATCAAAACAGGTAAAATTATATCGATGATGCTGATGGAACAAAAGCATGCAAGGTAGGCTTCTCAAGGTCTGATGTTTAGGCCACTAGGATCACACCTTCATCCAGTGTCAAATACAGTCAGTCATTTATCTGTCTCATTTTTTAGGCAAAAAAAAAAAAAAAAAGATATGCAAGTTTCCATTATTGAAACTACACACTCATGAAAATTCCACAGGGTAGATGCTGGTTGATTAGAGTCTAGAAATTTATATTCATGTCTCATTTCTTTGCATGCTGGCTGAAAATGTAATATGTGTATTTGTCCTTTTTCATAACTTTGATGAAAAACTGGCCAAAATGAAAATCTCTGCAATAACATTCTATAAAATTCTGAGATTCCACACAGGAAGTTTTGAGTCTTGAGGGAGCCTAATAAATACTATCCTTTTTCCTCATTTCCAAATTAGACTAGGATTCAGGCAGGAAACCAAAATATTATCTTTACTTGTAAAGGCTAGTTGGAAAATGTGGTAAAGCTGTGTGGTTTCCCAATATTGCATCCCAGAATTATACTTACACAAATATAGGTATGACAGGGCAGCCACCATCTTCCTCCATGGGGCTTGGCACTGGCACAGGTACAGCACTGAGGAACGGATCAAAAGCATGTTCTCTGCAGGCAGAAAGATGCCAGAAGAAAGACAGAAGGAGCTACTCATACCCAAGTCTTCTCAGAACTCTACAAAAAAATCATTTCTCCTCTGCTTAGCATGAGCCAAGCATGCTACTTTAATGGGTTCCCTCCACATAGAAGGTAGCATCCTCACCCTATCTGGGGGGGGTGGGGTGGCAAATGAACATGTACCTCCAACCTCCACATTTGTTGCTTTTAACCTACTGACTGAGCAAATTTATGCTTAAAAGGTATATTTCCAGACATTATTTGATCCTGTATTTCAAATAAGGAATAATTTGTTTTTAATTATTTGTAGATCTTGCTAAAAATGGCCAGTTTCTGCATAGAGAAGCTGAATGCATGTTGGAATATGTAGTGGACACTGGTGTGCCAGCCAGATCCCTTCATCCCCATCTTCAGGACTGACTCAGTCATTTCTTCAGCTACTGAGAGTGCTAGTGGCTGACAACTTACAGCTGAGCACGCCCCCCAACCCTACCTCCCCCCAACCCGGGAGAAGAGAAGAGTTTTCTCTTCTCCCGGGCCACATCCAATGCTAGGGGGGTAAAGCTCCATGCTAGGGGGTAAAAGTCAGCCTTGTTGCCCCATTGGAGACAACTCTACAAGCTATCTAGGGGTCTCTATGTGACAGCAATGACATCCACCTTTCTTCCCTGCCCTATTCTTCCTCCCTTTCCCCCACAAGTGTGCATCCCAATACCACCCCCACAAACCTCCTTCCAAGACTGCTTCCCAGGGACCTGCCACAGCATATTTTAAAAGGAAGTATATCCCATGTAGATTTCTGCATGTATTATTCCATGGAAAAAATACTCGATTTTACCCATCTAAATAAGCTGAACATTGAACCAAGAAGCCAGATTGAAAATACAATCTGGGTACTGGTGAAGGTTGTTTGATAATAAAGACACAGCCAAAACTGGCCCAATACAGCATGACATCTTCCCAGAAGGCCATTTGTCACTGCAGCTTCTGGGGTGCATTTGTGTAATTCGATATTAATGATTCAGGATTAGTCTTGGAAAAGTGCACAGGCAAGGCTTCTTTCACAGCTGTTCTTTGAGTGGGCTTTGATCTCATGTATTGTTTAAATGTGACTTAGAAGTGATGTTTTCTTCTCTATGGGGAAAAAAATAGCTGCAGAATTAAAAGATGTACTGGCACTTGACACTAATCACAAATACTACCAGCAGCCCGTCTTGAAAAGGAATTGTTATTTTAACACTAAGCCATGATTTTGTTTTCATCCTGCCCACAG
Seq C2 exon
GCCCAGGCATCCCCATTTCCACCCTTCATGATGGACGCACTGATCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078098-FAP:NM_004460:16
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0093016=DPPIV_N=FE(11.4=100)
A:
NA
C2:
PF0093016=DPPIV_N=PD(1.4=29.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)