HsaINT0063043 @ hg19
Intron Retention
Gene
ENSG00000119402 | FBXW2
Description
F-box and WD repeat domain containing 2 [Source:HGNC Symbol;Acc:13608]
Coordinates
chr9:123535032-123538504:-
Coord C1 exon
chr9:123538371-123538504
Coord A exon
chr9:123535119-123538370
Coord C2 exon
chr9:123535032-123535118
Length
3252 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGGA
5' ss Score
9.45
3' ss Seq
AACATGGTTTACATTTGCAGGTA
3' ss Score
7.88
Exon sequences
Seq C1 exon
TATTTAGCGTGGACTACAATGATGAACTGGATATCTTGGTGAGCGGCTCTGCAGACTTCACTGTGAAAGTATGGGCTTTATCTGCTGGGACATGCCTGAACACACTCACCGGGCACACGGAATGGGTCACCAAG
Seq A exon
GTAGGAAGACTTGGAAGAAGTCTCCTGCTTATCAGGCTTTTTGAGGGAGGGCGTGGAGGATGGTAGACACTGCCTTATAAGTGTTAGGTGAGTCATAAGATGGAATTGCTGTACCTACAAAGCATAATGGTACACAACAGTGACCAGCAAGTAGAAGGTACTTAATACATGGTTTAACAAATAAATGACTTATGGACATGGAAAGTTGCCCACAATATATTAGGTGGATAGAGGGGGCAAATAAAACAGATTACATACAAAAAAATATGTAGAGTGTGATACCGGTTTCTGAATGTGTTCATGCATCAAAATGTTGAAGGTGGGTATTTCTGGTGGGATTGTGGGCGTGTTTTTCCCTTTAGAATAAACATGTTTCTTTCTTAATCAGAAAAGCAATTTTCATTTTGAAAAAATAACGCTTACAAGAAGTAGGACAAAGAAAACTGTACAGGATCTTTAGTAAAATATTGTAATGTTTTCTTTTTTAAAAAAAACAAGATTGTTGTGAGGATCAAATGCAGTATTAATAATGGATATACCACGCAGAAGCACTTTTCTTGAGTTTACCATCCCATTCTATGAGGGGGCTGAGAAAACAGGAGTAAGCAAAATAGACCCAGTCCTTACCCTGTGGATGATAGTCTAATAGGAGAAATAGTTTTATTAAACAATTTCATGGGTAAATATATCATTTCAAATTGTGTTAAGTTTTGTGAAGGAACAGTACAGTGTTCTATAAGACAGTCTAGGGCCAGGCACAGAGGCTTACATGTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCACCTGAGCCCAGGAGTTCGAGGCCAGCCTGGCCAACATGGTGAAACTCCGTCGCTACTGAAAGTACAAAAATCAGCCAGGCGTAATCCCAGCTACTCAGGAGGCTGAGACAGGGGAATTAACTTGAAGCTGGGGAGGCGGAGGTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCACCCTAGGCAACAAAGTGAGACTCTTTCAAAAAAAAAAAAAAGTATAGGAAAGTAATTAGTTCAGAAAAAAGTTTTTGAGAAGGGGGTTAAACATGAAGAATAAATAGGAGATAGCTGTGGAAAGAGTAGCTGAAAGATTGTTTCAGAGGGTGCAATACATGCACGGGCCCAGCGGGTGGAAAGAACTTGGAACATTTGATGACCTGGACATAAGCCAGTGGAGCCATGCTGTAGTTGGGAAGATGGGCAGAGAGGTGGTAATCCTGTATGATTTATAAGGCCACAGTAAGTATGGTGGATATCATCAGAAGTGTACTAGGAAGCAATCCACGAGTTCTGAGCAAGTGTCTGGTGCGATCTATGTTTTAGGAAAATTAACTGCTGAATGAAGAATGGACTAGAGTTGGGCACAAGTGGATACAGGGTGACCATTTAGGCTTTGGCAGTAATCTAAGCAAAAGATGCCCATAACTTAGATTTTCCTGGCAATAATGAAAAGGGCACCCATAAAGGATATGTCTTTAAGGTAAAGCCACCTGGCTTGCAGATTCACTGTGGGAAACAAAGAAGAATCATTTGTTGTTGTTTTAATACAGACAGGGTCTCATTCTGTTGCCCAGGCTGGAATGCCGTGTCATGATCATAGCTCTCTGCAACTTTGAATCCCCAGGCTTAAGTGATCCTCTCACCTCAGCCTCCCGAGTAGCTAGCACTACAGCCACGTGCCACCACACTGAGCTAATTTCTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTTTCACTCTTGTTGCGCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAGCATCCATCTGCCGGGTTCAAGTGATTCTCCTGCTTCAGCCTCCAGAGTAGCTGGGATTACAGGCGCCCACCACCATGCCTGGCTAATTTTTTGTGTTTTTAGTAGAGACGGAGTTTCATTGTGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCACCTCGGCCTCCCAAAATGCTGAGATTACAGGCGTGAGCCACCGTGCCCAGCTGCTAATTAAAAAAAATTTTTTGTGTGTGGAGATGGGGGTCTTGCTGTGTTGCCCAGGCTGGTCTTGAACTCCTGGCCTCAAGCAGTCCTCCCTCCTCGGCCTCTCAAAGTGCTGGGATTATAGGCATGAGCCACTGTGCCTAGCCCATGTTAACTTTTTACATGGAAAAGCTATATAGTGTAAGGCAGTTTGGTGTTGTGGAAAATAGTTGATTGGGGCTAGGACACTGACGGTGATGTCTTGGACAAGTTACTCCACCTTCAGGACCTGAGCTGTGTCATCTGCTAAATGTTCCTGTGAACACGAAATGAAATGTTGGGACAGCACCCAGCAAGGTGCCTGATACTTAGTAATAGGTCTGTTTCAGTTGAGTCTGCAATCCAGACTTCTGAATGAGTGAACCCTGCTTCCCCTCTCACCTTAGCCTGATTGATTGCAAAAATAGCTAGAACCTGATGTTTATATACTTATCTCAAGTGCTAACAGAATGTTAGCTTTTATTTTGTTACTACTATAATTTACATTGTTACTTTATCTTTACTGTAATTAAATGAGGTAAGATAATAGGTGCTTGTCTCCTGTTTTAAAGATCAAGAAACTGACCGAGTTTAGATGGTCTTGTCCAAGGTTGCAAAGTCAGCATATGGCAGATTCTGGTCCCAAGTCCAGTGCTTTTTCATTTATGATTCACATAGTTATGAAAGCAGATCATTTGCATCTACGTCAGTGTCTACGGGCTTTTTTCTTTTCTGTTCCCTCTCTTAAGTTACATTTTATAATTTTAAAAAATCAGTCCTAATGTTTGCTTCTAGACGAATGCTAAGATTAAATGCTGCCAATGTTTAGACTGTTTTTTTTTTTTTTTAAGCGTTGTGGTCTTGCTCTGTTGCCCAGGTTGGAGTGCAGTGGTGCAATCATAGCTCACTGCATCCTCCAACTCCTGGGCTCAAGCAATCCTCCCACCTCAGCCTTCCGAGTCACTGGGATTATAGGCGTGACCCACCTCATCTGGCTAACGTTAGACACTTTTAGATACTGCTAATAACAGAGAATATTGTAGTAAAACTTTTAGTAGAGGTTAATTTGGTAATGGAGTTATGGCTTAGCTATTCTAGCATATGTTAAGCTCATTTTTGTATTTTAATTTAAAGAATAAAATCATTATAGGAGCAGCATTAAAAGGATCTTTCCGTAACATGGTTTACATTTGCAG
Seq C2 exon
GTAGTTTTGCAGAAGTGCAAAGTCAAGTCTCTCTTGCACAGTCCTGGAGACTACATCCTCTTAAGTGCAGACAAATATGAGATTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119402-FBXW2:NM_012164:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0040027=WD40=PD(64.1=55.6),PF0040027=WD40=PU(31.9=33.3)
A:
NA
C2:
PF0040027=WD40=FE(59.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)