HsaINT0076465 @ hg19
Intron Retention
Gene
ENSG00000198502 | HLA-DRB5
Description
major histocompatibility complex, class II, DR beta 5 [Source:HGNC Symbol;Acc:4953]
Coordinates
chr6:32489682-32498006:-
Coord C1 exon
chr6:32497902-32498006
Coord A exon
chr6:32489952-32497901
Coord C2 exon
chr6:32489682-32489951
Length
7950 bp
Sequences
Splice sites
5' ss Seq
GACGTAAGT
5' ss Score
10.93
3' ss Seq
GATCCTTCGTGTCCCCACAGCAC
3' ss Score
9.82
Exon sequences
Seq C1 exon
CCAGCATGGTGTGTCTGAAGCTCCCTGGAGGTTCCTACATGGCAAAGCTGACAGTGACACTGATGGTGCTGAGCTCCCCACTGGCTTTGGCTGGGGACACCCGAC
Seq A exon
GTAAGTGCACATTGTGGGTGCTGAGCTACTATGGGGTGGGGAAAATAGGGAGTTTTGTTAACATTGTGCCCAGGCCAGGTGCCTTAAGAAATTGTGACATTTTCTTCAGAGATTGCCCATCTTTATCATGGGATCCCAAATTATTTCCTCCACAAAAGGAGCTTGACTACTTGCCCTCTCCATGAGACTGTGTAAGGGGCCTCCATACAGGTCATTTCTTCTCAAATCTCCACCAATGAAACCTTTTCATCACATGTCCTCAGGGTCTTTAGAGGATTTAGAAATAAGGATGCTAAAATAAATTCCCCATACAGCACTTCCCTTTATTATGTTGACCTATGTCAGACAAAACGAGTTTTTTTCTGAAAATTTTGTGGGAGTCAAGGGAATTCAAAGGGTCTCTCCTAGACAATCCTGTGTTATGCCCTTGACAGAACCTGTGATATTGGCTCCTCTTCCTCATATGTGAGAATGGACCCAGTGGCCTCCCCATTACCTCCTTTCTTTTCTTTCTGAACTCCAATGTTTACCCTGTAATGTATGCAAGGTCTCTGACAGAAGTTATGCTTAGTGCTTTTTCTTATGGGGAAAAATCCTTGGAGCTGAAGCTGAGATCTTTAGTATGTGGAGTCACCCTACAGTTAAAGGGCATCTATGAGGTATTCTTTGGTGCCTAAAGGACTTAAGGCATCCTCTAAAAACCTGGCCCAGGTTAGAGTTTATTACAAATCTTTTTTAACCTTTCTATACTATTTGCTCCTATATCTCCTACATGCTCTAACTAGACATGACAGGAAGAGATTCAACTAACATAGGACAAATTATATGAAATTCTATTTTTGTAAGTCAAAAATAGTCAAATATCAGAAATTTGATAAGGTTAAAACTATATACTCTGTGTGGGGTTACAGAGAGAATGTGGACATTGTTCACATCTCATAGGGCTGAAAGTTAATGATCAAGTCCTGGGAACTCATTGTCTTACTGGGGTCTTGTCCTAAATTTCATAGGTTCACCCGTCATGCCCTCAGCTTTCCTTAATTAGCCATGTCTGCTTACCTCTTCCTCCAGTTTCTCTCTATTTTTCCCCAGCTATGTTGTCATCATATCCAGAAATCCCTAAAGCTTGCACAGATCCTTAGCACTATGAGATCCATTGAAAGAGATAATTTTTTTCTTTTTGAGATAGGGCCTGGCTCTGTCACCCAGGCTGTAATGCAGTGGTCCGATCTAGGCTCACTGCAACCTCTGCCTCCAAGACTCAAGCTATCCTTCCTCCTCAGCCTCCAGAGCAGCGGAGACTACAAGCCCAACTAATTTTGTTGGAGATGAGATTTCTGCCATGTTGCCCAGGGTGGTCTTAAACTCCTGGACTCAAACAATCCTCCTGCCTTGGCCTCCCAGCATGCTAGGATTGTAGGTGTAAGCCACCGCACCCAGGCACGGTGAATTCATTGCCCAGGCAATGAATCTCAATGAAAAATTTCTTTTTTCTTAAATCACTGTTTCTTTATCTGTGAATTCTTCTTCCAATTAGAAGGAGGAGAAAGAAGAAATTTGCCTGTATTTCTCACCGGGAGGAGAAGGATTCTAGTGTGACATCAAATTGAAAGAGTGCTGGAGCTCGAGCCCCTTCTTGCTTTCCAGGATCCTTGCAGTGATCAGTTCCCAGAACCATGGTTTATTAATATAAACCACAGTTATTTTTATCAGCAGCTACTCTGTACTGGGCTCCCTTCTAGGTTCAAATCATTCTATTTGAGTAAGATAGAGAGGGTCCCGACTCTCAAGGTTACACAAGAGTGGAGGAGACAGACACTAACCCAATAAGCATTTAACAAAGAAGAAAATTTCAGAGAGTCATAGTGCACTGAAGAAAAGACATCAGGTTTGTGGAAAAGAGAGAAATGGATTCACCTACTTTAGTTCATATGTCTAGAGAGCCCTACTTGAGAAAGTGACATCCAGCTGAGAAAACAAAATAAGTAGACAGTCGTGAAGATCTAAGGGACGAAAGTTCCAGGGAGACCGAATTGGGGGGGAAGCCCTGGTGTGGGAAATTATGTGCAGGGACAGAAAGAAGGCTAGAGGGACTGAAGTGAGCAAGCAAGGAAATGCAGTGGCAGAAGATGAGGTAGGATGCAGAGAGGAAGTCGGGAGCCTCATATCAGGCTCTGATGTCCATGGTAAGAAACTTGAATTTTATTTTATTTTATTAATTTATTTATTTATCTTATTTATTTTTGAGAGGGAGTTTCATTCTTGTTGCCCAGGCTGGAGTGCAATGGCATGGTCTCAGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGTGATTCTCTTGCCTCAGTCTCCCAAGTAGCTGGGATTACAGGTACCTGCCACCATGCTCAGCTATTTTTTCTGTGTTTTTACTAGAGACAGACTTTCACCATGTTGGCCAGGCTGGTCTTCAACTCCTGACCTCAAGTAATCTGCCCGCCTGAGACTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCATGGCCTGAATTTTATTTAAATAGATATGGGAAGCTACTGGATGGTTACAAGGAAAGTCAATTTATATTCTTTTTTTTTAATTTTTTAATTTTTTTTTTTTTTGAGATATAGTCTTGCTCTGTCACCAGGCTGGAGTGCAGTGGCACTATCTCGGCTCACTGCAGCCTCTGCCTTCTGGGTTCAAGAGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGAGTGCACCACCACGCCCAGCTAATTTTGGTATTTTTAGTAAAGACAGGGTTTCACCATGTTGGCCAGGATGGTCTTGATCTCTTGACCTCGTGATCCACCTGCCTCAGCCTCCCAGTGTGCTGGGATTACAGGCGTGAGCCACCGTGCCCGGCCTATATTGAATTTTTAAAACTAATTCTAGCTACTCTGTGGGGATTGGATTGTTGGGGTTGACAAGTGGTTAGGAAGACTATTTAGGAGCACAGCAGGGAATCCTCAGGGAAAATAGGCTTGAGTTCACTAGTGATAAAGACAGTGAAAAAGATAAAGTGGATTTTGCTTACCTTGTTAATGGATTACTGTAAAGGGGGTAGAAATATCAAGCTTATTCCTAAGGATTTTGTTTTGACAAATTAGTGAAAGGTGGTGGTGTTTATTGAGATAGGGAAAACTGTGGGAGGAAATGATTTGAAGTGGGTGGTTGGAAATAAAAGTTTTGTTTAAGTTTGAGATGATTTATTGACATTTGTGTGGAGCAATCAGAAGGTCAATGGCATTTAAAAGACTCATGGTGGGCCAGGCGCAGTGACTCATGCCTGTAATCCCAGCACTTTGGGAGGCCTAGACAGGCGGATCACCAGGTCAGGAGATCAAGACCTTCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGCATGGTGGTGGGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAAGCACGAGAATGGCGTGAACCAGGGAGGTGGAGCTTGCAGTGAGCTGAGATCACACCACTTCACTCCAGGCTGGGTGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAGAGACTCATGGTGAGGCCAGGGCTGGAGGTATTTATGTTGGTGGCATCAATAGGTGTACTGTGTTAAATTCCAGGGAGTGGAAGAGGTTACATAGGGAGATTGTCTGGAGAAAAAAGAAAAGGGCACAGGCCAGCAAAGGGGACTAAGAAAGAGCCCAGGGATGTTGGGAAAAAACCAAGATTACATCATATGTGTAAGTCAAGAAAAATAGATTTTTTTTTTTCAAGGAGAAGGGAGAGGCCAATTGTGGTGAGTACCACTAAGAGGAGGGTGAAGTGAGAATGTGACAGAGAAGCAACGGCTGGGATTGGTGGAGCTGATATTTGCAGTCAGTAGAGTATCCAGGGAGGAAACTGGATTGGACCATTTGAAGAGCGAGTAGAAGAGAGGACAAGGTTAAGGTTGACTGTTTTGAGTAGCGAGCTTCAGGGAAGGACTGTGCTCTGGGTTCAGGGAGCCAGCTGGATCAAAAGGAAAAGGCTAAAGAGGCTGAAGAGAAGCAGGAGGACCTGTGAACCAGAGATGCTCGGTCATTATTATCAAGGAAATATTAGAGGGCCCCTGTGTGCAGTGGTGACTGCTCATGAAGAGGTCACACAGCCAGTATTTCACACAGCCCATATTTATTAGTGACTTAGAATATACCAGTTACTACTCTAGGTCATGAGAATGGAGTGATGAATAAAATGAATCTGGTCTCCATCAGTATATGCCATGTAACATTTTGCAGTGACTGTGTACCAGGCCTATGAATTTCAGTATGCAATTTCAATAATGATCCTGCTGTATCTGTGGTATATAAAAACATGTACATCTCTGGAATCTAAAATTGAAAGGTTATAAGTAAAACCCAGTATCACAAATTTGGTGCTAGAAATCAGATTGCAGTTTAAATCTGAGCATGTAGAAAGTCCATTTCTTCTATGTCAGCAGGTGCCTTTTGTGTGAGGTTTAGGTATACTGCATTATTAGACATAAACCAGTGTTTCTGCCCTCTGTTTTCAGAATGACAATTCTTTATGAAACTAATAGAAGAACAGAAGACAATTGCAAAATCATGATGAAGATACTAATTGCTTTAGAATCATGTAATAGAAAAAATAATGTGAGCTCCAGTTATAGGGATCAAAAAATTAAAATGGGAATACATTTGAGTGTTTATTATGTGATCACTGCTAAGAAGACTCTTTATTAAATTTCACACTTACAAAAATCCTGTGAGGATTATTATAAAATGCATTTGATAGATTACAAATAGGCTTATGGTTGGCAAAAAGTGACCCATTTAAAAGAGGTCATATTTCAATTCATATTTTCTGATTCTAGAATATGAGAGTTTTTCCATCATTAGTGAGTAGTGACTTGATTGTGTCTGAATTATTGACAAAATTTCTAATATTCATATGTACCAGGTTGTTTCTTAGAGTGGGGGCAGAGATGCAAGGGCTTCTAGTTCCAATGTATAAAAGAAACTTTCATTCATTTTGCATTTATCATTTTAAAAGTTCTATAAGTCTATCATAGGCATGTGTTGAAGAACATAAAGAAGTATTAAATCATTCCTTCTTCTGAGGTTTGACTAGCAAGTCTGGCTAGGGTTGTCAGATAACAAACAGGTTCCTAGTTAAATCTGAATTTCAGACACACGACCACAATTTATTGGAAATCCAGATTTACCTGGGCATCCTCTGGTTTTATTTGTCAAATCTGTCAACCCTAAGTGGGACACATGAGCATGGATTACAGTGCTAGCCATGCAAGCCACAGTGACAGTGACTTTACAAATGTTTATTTTTTAACATTCTGTCTGTAAAGAAAGTGCTTACATAATTTAGGAATAGAAAGATAGACATTGTTTGATCCAGGGTGCACACCTCTCTGCCATCATTTCTAAAGGGCAAACGGAGCTTTGTGAAGGTCTCTACACAAAGTCTGGGGACCTGCTCATGTTTTGTAAACTGTCTGTATGAGAACGTCATTTTCTTGGTTTCTGACTTTCTGAGGGGACTTGACTACAAAACCAAGAGTTCTATCTCTGGCCAAGGCTGGTAATTTGATGCCTGCTAGTATTGTTGGGAGTGGGAGACTGAAAGACGTGAGTTAGTTGGGGCATTAAATGGGAATAAAATAGCTGTGGTTGTGATTCACTACTACAGATAATTAGTGGACAAGTGGCAGAGAAATTAAGAAAGAAGATGATATGAAAGACAAATGATATGATTTGGTGACTGGTTGGTAATGCAAGGAAATCAGTAAATCTTAGTTCTCAACAAGTTCATTTTCTGGAAAGATAGCACTGTATTGGGACCAGAATTCTATAAAGCATTCGTTTTATGTAGGACCAAGATATTCACAGATATTTTTCAATACAATTCTCAGCTGCTCCATAACCACTAGTGGCTTGTTCAACACAGGTTTTTTCAGATGGTTCACACCTGTGGTTCTTACCCAGGGATCGTTCACCACCGCTCCTTTCCCTCCCATCACCCTTGGGGAACTTGTGGCAATGTTTGAGCAATTTTTGGTTGTCACCACAGGGGTTTCTTCTGATATTTAATGAGTAGAAGCCAGGGACACTGCTAGAGAACCTACAATGTTCAGAACAGCCTCCTTTACCAACAAAGAATTATCTGGACCAAAATGTCAATAGTGCTGAGGCTGAGAGCACTGTTTCACACTGTGCTCTTTCTGAAAATTCTAGACTCACATCTTTTATACACTCAGCACCCAATTCAGTTCTTTATGGTTTATTTTTGCTTGCTTCATTATGCAAAAGTAGACAGTTGCATAAATTCAACCACTTTCTTGTTGAATCCATTTAGTCAATGCAAGTTTAATAGCTTCATAGTTAGTTTTTGCCTTATGCAATATTTTTCAACATTTTCATGAGTTGTTGGTCAGCACTACCTCTATTAACTTTCAACAACTTGCCCTTATAAGTCACAAATAGTGATGCTCTGCAATTATTTTTCACTAACATGCCTGAGATTTCTGTAGTGATTCTACATTTGGTATGATTCATAATGTAAAATGCTTTTATTTATTCATTTCACTTTTAACCAGAGGATTATTTTTCAGTTATTTTTGTCATTTTTACACTTCAATCAAACATAAAGACAAAAACATCTAAAATATATAGTATTTTACATATGTGTATATTTACACACATATATGTATGTATGTTTACATGTATTGAAACTACAGAAGCTCATGTCACCAATAAGAGCTCTGAGACACTTTTGACCCCTTACTCTTATCAGGTGAAATTTGCCAAATAAGTTTTATGAACAAATTTCTTTTAACTGAATATCTGAGCTTTGTGGATTTAGAAATGCAAAGGAAGGTTTGTGGACATTCATGGGATCATGGTTTTATTCTCCTTAAATCTCTTTGATACTTTCCCACTGTCTTTAGCATAAATCTCAGATCCTAACACCACCCACAACGCTTTTCAATACCTGGCTTCTTGTGATGTCTCCAGTCTAATCTTTTACCCTCCTTCCCCTCAGCCTCTCTGCTTTAGTGAACTTTGTTCTAGTTTCTTGAAGAAGTTCATCAATTCAAGCTTTTGTGCATGGTATTTCCTAAACCTGAAATGTGCTTCCCCCGTTTTGCCCAAACAGACACAGAGTCTCCACTCCGCCCCCTGGTTCACACCTGCTTAACCTGCCAAGTCACATCTGAACTGTCACCCTTCAGAAGGTCCTCCTCTGGCACCCTAATGTAATTGAGATCATCCTATTACTCTGTGTTCTGGAACTCCACACTTCAGACATTTCTCATTCCTGTCTAAGCTCTTGTGTGTTTGGTTTTTGGCCTCACTTTTACTGCTCTTTAAGCTCCCCCAGCGGAGTGGAGAGGTCTGTTTTCCCGTGTTTGGATTCCCAGAGGCAGTGCAAGCCTGGCACAAGGTCATCACTAAAGGAGTGTTCACAGGATGAACGCGGTGGGAGTTAGGGAACGGGTAAAGCCTGTGGGATGAGAGAAGGAGCAGAGATTGTCTTTGGGGTGCAGGCTCCCAGGAGGAGGCGGCGCGGGCTCCGGTGCTGGGCGGATCCTCCTCCAGCTCCTGCTTGGAGGTCTCCAGAATAGGCTGGAGGCGGGGAGGGGGTCCCAAAAGCCTTGGGATCAGAAGGGGTTTTCCTGCCTGGTCCCCCAGACACCCCGTTCGCCTCAGGAAGACGGAGGATGAGCCTCTGGGCTGCGCGTGGTCGGGGTTATGGTTGGGATCAGTTAAGGTTCCAGTGCCCGCACCCCGCCCAGGGAGCCCCGGATGGCGGCGTCTCTGTCAGTATCTTCCCCGGAGGCCGCCCCTGTGACCGGATCCTTCGTGTCCCCACAG
Seq C2 exon
CACGTTTCTTGCAGCAGGATAAGTATGAGTGTCATTTCTTCAACGGGACGGAGCGGGTGCGGTTCCTGCACAGAGACATCTATAACCAAGAGGAGGACTTGCGCTTCGACAGCGACGTGGGGGAGTACCGGGCGGTGACGGAGCTGGGGCGGCCTGACGCTGAGTACTGGAACAGCCAGAAGGACTTCCTGGAAGACAGGCGCGCCGCGGTGGACACCTACTGCAGACACAACTACGGGGTTGGTGAGAGCTTCACAGTGCAGCGGCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198502-HLA-DRB5:NM_002125:1
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0096914=MHC_II_beta=WD(100=82.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)