HsaINT0082831 @ hg38
Intron Retention
Gene
ENSG00000160255 | ITGB2
Description
integrin subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:6155]
Coordinates
chr21:44889978-44891996:-
Coord C1 exon
chr21:44891809-44891996
Coord A exon
chr21:44890223-44891808
Coord C2 exon
chr21:44889978-44890222
Length
1586 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
GGGGCCCCTCCTGTCCCCAGGTG
3' ss Score
10.24
Exon sequences
Seq C1 exon
ATCACCTTCCAGGTGAAGGTCACGGCCACAGAGTGCATCCAGGAGCAGTCGTTTGTCATCCGGGCGCTGGGCTTCACGGACATAGTGACCGTGCAGGTTCTTCCCCAGTGTGAGTGCCGGTGCCGGGACCAGAGCAGAGACCGCAGCCTCTGCCATGGCAAGGGCTTCTTGGAGTGCGGCATCTGCAG
Seq A exon
GTGAGGCGGGCGCAGGTCCCTGTTGAACCATCCCCGAGCCCCACCCCACAGGGCAGGTGTCGGCAGGTGAGGTGGGTGCAGGTGGCTCCATCCCTTCCCCCACCCCACGGAGCAGGCATCCTGGGGGCCCCCTTCTGCAGGAGGTGGGGAGATTTGGGATTGGAACCCAGAACCCCTCGGCAAGCCCTCACCCGTGCTCCTGAGCCAGGGCACCAGCAATGCCAGCCTGTACTCTACACTCTCTGGCCATGGAGGACCCAAGGCAGGGGACTTGTGGGCAGGAGGACCCCCTCACCAGAGGATGGAGGCCCATCTCAGGGGCACAAGGAGTCCCCGCTGGGCGTGCCCATGGCCTTGAGTGGGTCACTTTCTCTGCCCGACCTTCCTTGACCCTAGGAGCTGGCTTCTCTCTGACCTTGGGGACCCAAGGCCATCAGGCTGGCAGCCCTGGGGCATGGGTGGCTAGAGAGCCTCCTGGGACAGGTGATGGCTTCTGGGAGCCTGGGCCCCATAGGCCACCTCTTGGGCGTGCACACCCCCTGCCAGGCGTGGGCACCCCACCTCAGGGAGAAGTGGGGGACAGGTGGACCCAGTGGGGAGGTTCACATGGCACTCAGCCAGGCGGCCTGCCCGGGGGCTGGATGGCTGTCCCCCTTTCCTTGCTTGCCTGGCCAGAGCTGCTAGGCTGACCTCCCAGGACTCTGCCCCCTTTGCTCTGGTCACCTCCTCCCCTGTCCTGACCGCAGTGCCAATCCACGTCCTGGTGGCAGTGCCCTTCCTCACCTTCAGGTCCCTGCTGCCCCCAGCCTCCTCCCATATCTCAGGACAATGATGGTCTCTGTGGTCTTGGTGGTCTCTGTTGCTGTCCTCGTGCCTCAGTGGCCACCCCGCCCACTGTCCTGGGTGTGCAGCCCTGGGGCGGCCTCTTCACGGGACTGTAGGGGTGACTCAGTCGGAACACTTGGCAGGTGTCGGGGGGTGCCCTGCCACAGGTACTCAGACACTCGGTCCTGCAGCTTCCTCCTCTGGGGAGCAGGAGAGCCCGTGGCAGTGCCGTCTCTGAGGATGCCTCAGGGTGTGTGTGGCTCCTGCCTGCCAGCGGCTTGATGCCAGCTTCCACATCTGTAAAAACCCCTTGTCCCTGCATTCTCCCACAACCTGGCCTGTCAGTGCACGAACGCAGGAGGGAGGGCGGGGCTGTGGCAGGAGGCAGTGCCGAGTCCCCACTGGCCACCATGTGGGGCACGCAGGAGCAGACACCAGCCACTCACAGAGCACCGGTATCGCAGCACAGGCCATGTGCATGGCTGCAACACAGCTCCACAGTGAGCCTGCCGAGCCACTGCATGCGCAGGCCAAGGCCAGGTGTCTGCTTTCCCCTCGGGACATCCTGGGGAGGGAACGCGGGGCCCCTGCACGTTTTGAGCACATTTAGTCCGTGGCAAGTGCTCAGTAGGCCTCGAGGAAAGCAAAATGTGCCATAGGGGTGTTCTCCACCAAGGGCAAGGGGCCTGGAGGACAGGGCGGCTGTCCCTTGTCCCACATCACTGGGGGGAGCCTGACCTTGGGGCCCCTCCTGTCCCCAG
Seq C2 exon
GTGTGACACTGGCTACATTGGGAAAAACTGTGAGTGCCAGACACAGGGCCGGAGCAGCCAGGAGCTGGAAGGAAGCTGCCGGAAGGACAACAACTCCATCATCTGCTCAGGGCTGGGGGACTGTGTCTGCGGGCAGTGCCTGTGCCACACCAGCGACGTCCCCGGCAAGCTGATATACGGGCAGTACTGCGAGTGTGACACCATCAACTGTGAGCGCTACAACGGCCAGGTCTGCGGCGGCCCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160255:ENST00000355153:11
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0036213=Integrin_beta=PD(13.1=60.3)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGGCTTCACGGACATAGTGA
R:
CGTTGTAGCGCTCACAGTTGA
Band lengths:
345-1931
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development