HsaINT0082834 @ hg38
Intron Retention
Gene
ENSG00000160255 | ITGB2
Description
integrin subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:6155]
Coordinates
chr21:44886736-44888895:-
Coord C1 exon
chr21:44888693-44888895
Coord A exon
chr21:44886903-44888692
Coord C2 exon
chr21:44886736-44886902
Length
1790 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGG
5' ss Score
8.41
3' ss Seq
GTGTGCTGCTTCTTCCCTAGAGT
3' ss Score
9.54
Exon sequences
Seq C1 exon
CTCCTGCGCCGAGTGCCTGAAGTTCGAAAAGGGCCCCTTTGGGAAGAACTGCAGCGCGGCGTGTCCGGGCCTGCAGCTGTCGAACAACCCCGTGAAGGGCAGGACCTGCAAGGAGAGGGACTCAGAGGGCTGCTGGGTGGCCTACACGCTGGAGCAGCAGGACGGGATGGACCGCTACCTCATCTATGTGGATGAGAGCCGAG
Seq A exon
GTGAGGCCGCTGGGGTGCAGCGGGGACCGGCTCCAGAGCTCCGGCTGCGGGGTCTCCGCAGAGGCGAGGGTGGTGCGGAAGGAGGATCTCACCTCCAGTGTTGTGGGCCCAGCAGGGTGGATGAGCCATGCGGGATGCCCTTGGCATTGCAAGGAGGCCAGAGGCCGGTCCCCTCACCCCCAGCAGCCTCCCCTTTCCCTCCCCTCCTCACCTGACCCCACATCAAGCTGGGCAGCAGACGGCCTGCTCCCTGGGGGCACCACTGCTCCACACCGGGCAGGCCCACCAGCATGCCACACGGCCCGGGCCATCTCCCGCTGGATGCCTCATGGGGCAAGGCTTGCAGTTGCAGGTCCCCAGGGGTGGCCCGCGGTCAGGTTGCTGCGTGAGGCTCCTTTGAGGGGATTGGGAGATCCTGGTGCTCGGCTCTCAGCCCTGGAGGGGCCCAGGGCCACCAGGCACCACCGTCCCCATCACTCGTTCGGCTCCAGTCCAGTCGGAACCAGTCCCAGCCCCACAGTGACCTTGGTGGCACTGACCCTGTCTCATTCGGCTCCAGTCGGAACCAGTCCCAGCCCCACAGTGACCTTGGTGGCACTGACCCTGTCTCATTCAGCTCCAGTTGGAACCAGGCCCAGCCCCACGGTGACCTTGGTGACACTGGCCCTGCTTCTTCAGGTCTCATGTTCCACAGGCTCCTGAGAGGCAGAGGGGCTGGGGCTGGGGGGCCGCTGGCGGACTCCATCAGGCATGGCCAGCAGCCGGCCAGGACTCTTGCAGAACTGAGACCTGGGAGCTCCTCCCTCACCAGGAAGGGACCCGAGGCAGGCGGCGGGGGTCTCTGAGCCTGTAGGTGACATGCCTGGAGCTCACAACCCACATGTGGGCCTGGGGCTGCAGACCCCCACCTGCCAGGGCAGGAACCCCTGCGGGCCACTTTGAGGGACAGACTTGGGTCACGTCTGGTTTGTGCAATCCTGGCCAAGTCACTTCACCTTTGAGGACAGGTGAAGGAAGGCAGGTCCCCCAGGAAAGGCAGGATGGCAGGAGGGGGCACGGGGAGTGAGAGTGCAGGTCAGGATGGCAGGAGGGGGCACAGGGAGTGAGGGTGCAGATCAGGATGGCAGGAGCAACCACAGGGAGTGAGGGTGCAGGTCAGGATGGCAGGAGGGGTACAGGGAGTGAGGATGCCAGACCAGGCCAGGGACTGCACTGAACGCTAGTGTCTGTCCCAGGGTCAGCAGCTGTGGGCCTGGCCCACTATGGCCCACAGTCCCCATGCTCAGGAGGTGGGCACAGCTGCCGTGGGAACCAGGACCTTGCGTTGCTCATCCTGGCACCGGCCTCACCTGCTGAGCTCTGGTCTCTGGTCTTGTCCTTGACGACCACAAATCACTTTCACAGTATGGGGAGTGAACTCCAGCAGGGACCCTGAGCCTGGTTCTGAACTCTGCTGTAGGAGAGCGGGGTCCCTCGCACTGTGTCCTACCCCCCAGTATTAGCACTCTGTCCTGGCTGCCCGGTACCCTGGCCCTGCCTTCTTCTCTGTCAGCAGGGGTGGTGGCAATGGCCCTTAGGTTTCATTTGGAACCACAGGGCCTGGCCTGGAATCCAGCAGGGGCTGGGCCAGGTTCTCACTGACCCCTGGCCATGGTGATGGATGGTGAGCCGGGGCCCTGGGAACCTCCGTCTCTCTAAGTGCTGTGTTGTGGGGTGACCTCGGACCTGTGGGCACACGGCTCAGTGAGATGGGGCTGGACTGACGCTCAGGTGTGCTGCTTCTTCCCTAG
Seq C2 exon
AGTGTGTGGCAGGCCCCAACATCGCCGCCATCGTCGGGGGCACCGTGGCAGGCATCGTGCTGATCGGCATTCTCCTGCTGGTCATCTGGAAGGCTCTGATCCACCTGAGCGACCTCCGGGAGTACAGGCGCTTTGAGAAGGAGAAGCTCAAGTCCCAGTGGAACAAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160255:ENST00000355153:14
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF079657=Integrin_B_tail=FE(86.1=100)
A:
NA
C2:
PF079657=Integrin_B_tail=PD(7.6=10.7),PF087256=Integrin_b_cyt=PU(54.3=44.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCGAGTGCCTGAAGTTCGAAA
R:
AGCTTCTCCTTCTCAAAGCGC
Band lengths:
343-2133
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development