HsaINT0090377 @ hg38
Intron Retention
Gene
ENSG00000091136 | LAMB1
Description
laminin subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:6486]
Coordinates
chr7:108001558-108002971:-
Coord C1 exon
chr7:108002849-108002971
Coord A exon
chr7:108001734-108002848
Coord C2 exon
chr7:108001558-108001733
Length
1115 bp
Sequences
Splice sites
5' ss Seq
TAGGTAATT
5' ss Score
7.27
3' ss Seq
GTTGCCTGTCCTTCCCGCAGCCC
3' ss Score
10.64
Exon sequences
Seq C1 exon
AAAGGAAGACGGGAAGAAAGGGCAGGCGGCTCGGCGGGCGTCTTCTCCACTCCTCTGCCGCGTCCCCGTGGCTGCAGGGAGCCGGCATGGGGCTTCTCCAGTTGCTAGCTTTCAGTTTCTTAG
Seq A exon
GTAATTCCGTGGAAACGGTGCGGGGAGGCGGACGGACTTGGGCATGGGGAAGGAAAACCCAAAAGCTGCTTGCTCACCTTCGTGGGATCCTGGGGGCTTGGGAGAGGGACTGGATGGAAATGACGCCCCTGGGATTAAACGCCACCGCCCTTGCTTCGGTGGTGGCTGGAGACAGCGCACGCGGAGCGCCGCGGACCCTCATCCCCCGGGCTCTGCGCCCAAGCCCCGGCCCCTGCGGCCTCCCGCGGCCCCCGCTCAGGGTTTTGCACCCTCGGCCGGTTCACCCTGGGTTTCCCCACCGCAGAGGGCAGGTTCCCTGGGGTTGGCGGTGCTGACCGAGGAGGGCTCTCCAAAAATCCATTGCCCAGGAGAGTGCCTGAGCTGAGCGGAGGCTTCATTCTGGGAACAGATGGGGGCCATGTGGCTTTAATTAACCATCTCTGTTTGTCTCCGGATGGCACCAGAAACAGCAGGACCTGGCGCTTCCCTGGAATGGAGAAGCCTTGAAACCACTCCAGAGCCCCAGGGACTGTCCATGGGCTCCCCTAGCTCCGGAAAGCGGCGTCCACCGCGAGCCCCGGCGCCTCGTCCCCAGCGAAGCGCCGGTGACCCTCGCGCGTGCACGCACACGCACTCTCGCTTCCCAAGCTCACAGATCTCCACGCGCACACTCACACCGAGGATGCGCGGGCTGCCGCGTGCACGCGGGTTCACGTGCGTGGGTGTGTGGCCCTTTGGGGGTCAGCCTCCCTGCGCCGGGCTCCGGACACGTCGAAGTGGAGGGTCTACACATCCACCCTTTGTTGGGGGAGCTGCTCCCCGGGGCTGATCAGGGTGGGCGCGAGCGTCGGTGGGTTTCCCGGGAGGGAGGCTCTCGCTGCTGGACAGACCTGATGACGTGTGTGGGTTTCTTTCCGTGTCCTTCTCCTTTCGGAGTCCCTGCCTTCCCAGCCTCTCCTGCGCTCATCTCTCCATTGTCTTTTCTGTGCATTTTGCTTTCTTCCGAATGGACTGTCCTCTCTCCGCACCCACTCCCCCGCCCCCGCTTGTTCGTTTTTTTCGGGCTCCACTCCCTGCTTGTGTCCCCCCAACTCTGTTGCCTGTCCTTCCCGCAG
Seq C2 exon
CCCTGTGCAGAGCCCGAGTGCGCGCTCAGGAACCCGAGTTCAGCTACGGCTGCGCAGAAGGCAGCTGCTATCCCGCCACGGGCGACCTTCTCATCGGCCGAGCACAGAAGCTTTCGGTGACCTCGACGTGCGGGCTGCACAAGCCCGAACCCTACTGTATCGTCAGCCACTTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000091136:ENST00000222399:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0005512=Laminin_N=PU(15.3=61.0)
Main Inclusion Isoform:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGACGGGAAGAAAGGGCAG
R:
TGCAAGTGGCTGACGATACAG
Band lengths:
294-1409
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development