HsaINT0090383 @ hg19

Intron Retention

Gene

ENSG00000091136 | LAMB1

Description

laminin, beta 1 [Source:HGNC Symbol;Acc:6486]

Coordinates

chr7:107577538-107580803:-

Coord C1 exon

chr7:107580434-107580803

Coord A exon

chr7:107577723-107580433

Coord C2 exon

chr7:107577538-107577722

Length

2711 bp

Sequences

Splice sites

5' ss Seq

AGAGTAAGT

5' ss Score

9.35

3' ss Seq

GCTTAACTTTCTCTTTACAGGAA

3' ss Score

10.86

Exon sequences

Seq C1 exon

CCTGTGACTGTGACCCCAGGGGCATTGAGACGCCACAGTGTGACCAGTCCACGGGCCAGTGTGTCTGCGTTGAGGGTGTTGAGGGTCCACGCTGTGACAAGTGCACGCGAGGGTACTCGGGGGTCTTCCCTGACTGCACACCCTGCCACCAGTGCTTTGCTCTCTGGGATGTGATCATTGCCGAGCTGACCAACAGGACACACAGATTCCTGGAGAAAGCCAAGGCCTTGAAGATCAGTGGTGTGATCGGGCCTTACCGTGAGACTGTGGACTCGGTGGAGAGGAAAGTCAGCGAGATAAAAGACATCCTGGCGCAGAGCCCCGCAGCAGAGCCACTGAAAAACATTGGGAATCTCTTTGAGGAAGCAGA

Seq A exon

GTAAGTAGTTAATGAGCCAGAGGAATTACTCATAAAGCTGAAAAAATATTGTGAGTTAACAGCAAAGATTTCCTGGCATGGTGCTTCCATCAGGAGGTTTTGTTAGTCCTGTGGGTGAGAACAGATTCTGAGCCATTTATTTTCCAGCAGTCTTGACTGGGCATTTGGGTGAGTGAACGTTGGCACATCAGTGGGGACCAGCCTTCTGGAGGCTGCAGTACAGAATATGCAAGCATTATATTCAGTGCTCCTCCTTGCAAATCATGTTCTAAGTCAGTAAAATGGGAGGAATGCTGGATTTAGAAGACAAAGATCCATAATTGAGTCTTGGCTCTGATGCTAGGCTTGTGAACTTGGATGACTCAATTCCTGAGCCTGTATTTTCTCTCCTGTGGAGAAGGGGTAGGATAATATATGCCATTACCTTATGAAGTAATGAAAGGATTTATATATAAAATAACAACAGGATTGCAGAAAATTATAAATTAAGTATTGCTACTATGGGGGAAATTCCATTACCTCAAAATAAGACTGCTTACTTCAAGTTTTTTCTGCTTCTCCGCCATTAGTCCACCAGACCAGTGCTTCATTCATCTAGTTATAACAGCTGCTCTATGCTGAAAAGTCCTCATCCCACCCCTTCTCTAGGTAATCTTCCCTCTGATTGGACAGTGTTTGTTAGTGGAAGCCTAGAGAATTGACCTTCTCAAGGATCATTTATCTACCCTTTCTCCTACCTCCCCTCTCTTGCCCCTAAACTTCCCAACTCCTTTTGCCAAAAAGGAACCCCCAAAACAGCACAATAAGACCTAAGTGCTAAAGGACAAAAATAGAAAAGGGTATGAGGCATCTGTGCTTCCCTAGATGCTATGGTTTTTTCACTGCAGACTCACCATCTAGGCCTGAGGGGACTGCTTCACAGTTAAATCCTGCACACTGAGGTGTTTATATGACGAAATGACAGTAACATTTTTTGTGTGTGATGAGACTTTAATCAGCACCTTTAAGAAGCCAGAGGGACTTTTCATCTCATACCAGGCATGAGTAGCAGAGGACAGCTGACATTAGCTCAAGCGACTTGAAGGAGGTCCTTCCTAGACCTAGATTTAAAGTAACTGGACCTTGATGTCAAGCCTTGGGTTTTATGCCCAAGACCATGTAGCTGGCCAGAGTGTTAGGAAACGTCTGATGTAGAGTGACAATGCATTTAGTGAGGCATTTTACCTCACTGAAAAGACTAAGCCTCCTAATGTGCAGAGATCACAGTTTTGGCAGGCCGTGGTCCGAATGCAAGCCCATTTAGGAAATGATCCTTGGCCTGGGTCTTAGGCATCTCTGGGAGGAAGAAAAAAATCTGGTGTCCTTTGAGAGCCTGCCAGAAGAGAGATTACATTCCCAAAACAGCTCTGTTTCTACCGTCACTATTCATTTAACTAGACAGATTGTAATAATCACAGGAAAACTAGTTCCATTACTCTTTTTTTTCAACATACTATCCAAGGATACATGTTTTAGGAACCAAAGTGGCCTTATTTTAAAATACGATGTTAGATTTGCTTGTTTTAAAAAAAATTGTATCATTTTATGAGACCTGAGAAGAAATGAAAGCCTTCTGTGAGTCATATAATTAATAAAAGCAAAGCACTGAAAAAAGAAACTATGTATATTAGCCTCAGGAAAAAAAGGCACTGAAATGTAATTTAATCTACCATTTTAAACCATCCCTTTAAGTACTTTTTCTTTGAGTTGGGTTATAGTTTTATCTCAGCCTTACATATCATTTTTCTAATGGCTCCCAACCTTTCAGCATCTTTACATTTTCCTGGTTTTTTATACTATTATATCGCCAAGAAGACAATTACATTCAATTAGGTGAACCAGTAATACCCAGAGGTAAAATCTGCTCAAATATTACTTTCTTTACAATACACATACAACCCTACCCACACCCACCTGGAGCACACTCGCATGTGCACACACACACCCATATCCACACTATGTACACAATAATATACAAATAGATGTCAAAAGTACGGCTTTGTAGGTTTGAAAGTACAGAACAAAATGCAGTTTAGATTCCAAATTAAATACTGTGAAAGCTAAATCTTCTTATTTCATTCTTAGTAGATGCTATTTTCTTATAAAAAATAAAAAGGCTGTTGGTAGAAGGAGGCCCCTCTGACGGAAGAGAGGAGTGTATGAAAGCTGATACTGGTGGCTCCTGTTGTCTTTGTGGCAGGCTATAGGGCTTCCCCTCTGCATGTTCCATCTTGAAGGAGATCCCTGAGGCTTAGGGAAGAATGTTTTGGGCTTGTGGCTGGGAGGCCTAATTGTATAACTGGAGTCATTTATGTCTTCAGTTTTCACAATTGTAAGGGCTTGAAGCTGCCTGTGAATAGAGCCAGAACTCCACACTCTGACCTGTGCTCATCTTACAGCAGAAATTTGGAATCCCTTAAATGGCTTGTCTGCCACAACTCAGCTGAGTGGTACTTCTGTGTTTCTCTCAAAAGTCATTGAACAAAGAAAAATTGTTAGATTTAATACTATCTGTTATAAGGAAAATAAAACTAGCACTTAGGGATGAAATGTTACAAATTACTGAATTGGTTTGAAATTAGTAATGGATACAGTACTAGTAGAAAATATGAAACGTGAAAGTTCTCCCTTGGGTTTATTTTATGTAAGTAAGCTTAACTTTCTCTTTACAG

Seq C2 exon

GAAACTGATTAAAGATGTTACAGAAATGATGGCTCAAGTAGAAGTGAAATTATCTGACACAACTTCCCAAAGCAACAGCACAGCCAAAGAACTGGATTCTCTACAGACAGAAGCCGAAAGCCTAGACAACACTGTGAAAGAACTTGCTGAACAACTGGAATTTATCAAAAACTCAGATATTCGGG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000091136-LAMB1:NM_002291:25

Average complexity

IR-S

Mappability confidence:

NA

Protein Impact

ORF disruption upon sequence inclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.000 A=NA C2=0.455

Domain overlap (PFAM):

C1:

PF0005319=Laminin_EGF=PD(0.1=0.0),PF0005319=Laminin_EGF=WD(100=41.1),PF041117=APG6=PU(54.5=62.9),PF0154413=CorA=PU(50.4=53.2),PF061607=EzrA=PU(43.2=33.1),PF057146=Borrelia_lipo_1=PU(46.7=45.2),PF0157614=Myosin_tail_1=PU(47.5=45.2),PF0001516=MCPsignal=PU(37.1=29.0),PF064286=Sec2p=PU(11.0=6.5),PF0003816=Filament=PU(35.8=30.6)

A:

NA

C2:

PF041117=APG6=FE(43.4=100),PF0154413=CorA=FE(47.3=100),PF061607=EzrA=PD(55.8=84.1),PF057146=Borrelia_lipo_1=FE(51.7=100),PF0157614=Myosin_tail_1=PD(51.7=96.8),PF0001516=MCPsignal=PD(61.9=95.2),PF064286=Sec2p=FE(84.9=100),PF0003816=Filament=FE(58.5=100)

Main Inclusion Isoform:

NA

Main Skipping Isoform:

ENSP00000377191