HsaINT0090489 @ hg38
Intron Retention
Gene
ENSG00000135862 | LAMC1
Description
laminin subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:6492]
Coordinates
chr1:183124631-183125550:+
Coord C1 exon
chr1:183124631-183124876
Coord A exon
chr1:183124877-183125396
Coord C2 exon
chr1:183125397-183125550
Length
520 bp
Sequences
Splice sites
5' ss Seq
AAGGTAATC
5' ss Score
7.46
3' ss Seq
TCTCTGTCTTCCTGCCTTAGCCT
3' ss Score
7.91
Exon sequences
Seq C1 exon
GTAAGAGATGTGAGCTCTGTGATGATGGCTACTTTGGAGACCCCCTGGGTAGAAACGGCCCTGTGAGACTTTGCCGCCTGTGCCAGTGCAGTGACAACATCGATCCCAATGCAGTTGGAAATTGCAATCGCTTGACGGGAGAATGCCTGAAGTGCATCTATAACACTGCTGGCTTCTATTGTGACCGGTGCAAAGACGGATTTTTTGGAAATCCCCTGGCTCCCAATCCAGCAGACAAATGCAAAG
Seq A exon
GTAATCAGCCTTTGATCAGATTCTGTCACAGCTAAATGCCCCTTTATTGTGAGAATTCTTGTGTGTCTCTTAAAATATGTATAGTTGTTTAGTCCAATAGAAATACATTGTGAACCGCTTTTGTCTTTTAAAATTTTCTAGTCACCACATTAAAAAAGTATAAAGAAGGACAGTCATGGTGGCTGACACCTGTGGTCCTGTAAAAAGAAACAGGTGAAATGAATACTAATGTATTTTATTTAATATATCCAACATATGATTTCAATAAGTAATCAATAAAAATTGTTAATGAAATATATGTTTTTTCTCACGCTAAGCCTTCAAAATCCAGTGTGTATCTCACGTTTATAGCACATCTCAATTCAGACTCACCAGCCACATTTAAAGTGCTCAGTAGCCACATGTGACAGCAGCTACCAACCTGGCAACACAGGTCTAAAGAATCTCTTTAGGTTGTTTATATTTTAGTATTTCTCTCAGGTGATTTGTGTCTTTTGCCATCTCTGTCTTCCTGCCTTAG
Seq C2 exon
CCTGCAATTGCAATCTGTATGGGACCATGAAGCAGCAGAGCAGCTGTAACCCCGTGACGGGGCAGTGTGAATGTTTGCCTCACGTGACTGGCCAGGACTGTGGTGCTTGTGACCCTGGATTCTACAATCTGCAGAGTGGGCAAGGCTGTGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000135862:ENST00000258341:14
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PD(42.3=26.5),PF0005319=Laminin_EGF=WD(100=65.1)
A:
NA
C2:
PF0005319=Laminin_EGF=WD(100=94.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTAGAAACGGCCCTGTGAGAC
R:
CTTGCCCACTCTGCAGATTGT
Band lengths:
342-862
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development