HsaINT0090490 @ hg38
Intron Retention
Gene
ENSG00000135862 | LAMC1
Description
laminin subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:6492]
Coordinates
chr1:183125397-183126262:+
Coord C1 exon
chr1:183125397-183125550
Coord A exon
chr1:183125551-183126119
Coord C2 exon
chr1:183126120-183126262
Length
569 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGA
5' ss Score
7.66
3' ss Seq
TGTCCTGTGTTCATTTTCAGGTG
3' ss Score
13.19
Exon sequences
Seq C1 exon
CCTGCAATTGCAATCTGTATGGGACCATGAAGCAGCAGAGCAGCTGTAACCCCGTGACGGGGCAGTGTGAATGTTTGCCTCACGTGACTGGCCAGGACTGTGGTGCTTGTGACCCTGGATTCTACAATCTGCAGAGTGGGCAAGGCTGTGAGAG
Seq A exon
GTGAGACATAGGTGCCTTTGGTGAAAGTAATCTTTGCTTTTTCTGTTATAAAAAATGAATTTTTATAAGTACATTTAATAATTGACTGTTCAGAAATTACTGGAGCGCCTAATGTAGGCAAGGCATCCTTCAGGGGCAGTGCTGGAGAATTGTAATAAAGCTAATGAAAGAAAGGAGTGGAGCACAGTGGCCCCAGCTGTGCCAGAATCACCTGAGCAACCTTTTAAAAGCACAAATTGCCGGGTCCTTTCTGAGGCACTTAGAATCAGACCCTTCAGGGTTGCAGCCTGGGAACTTCTGTTTTCAAAGCTGCTACTTAGTGTCCATACAGTCCCAGGCTGGAGAGCACTGGTAGCAGTTAAGTTAGGAAAAGAGGTTCTGAATAGCACTCATGAAAATTACTTGAACCTTAGGGGCTTAATAACCCTTAACATTCCATCTTAGTAACCCTTACCATTCAGTTTTCTGATACAAGTTACAAATTACATCAGTGCTATACTAAAAAAAAAAAAAAGTTGTGCTTAAAGTCTGTTTTTCTTGCCTGAGAAATGTCCTGTGTTCATTTTCAG
Seq C2 exon
GTGTGACTGCCATGCCTTGGGCTCCACCAATGGGCAGTGTGACATCCGCACCGGCCAGTGTGAGTGCCAGCCCGGCATCACTGGTCAGCACTGTGAGCGCTGTGAGGTCAACCACTTTGGGTTTGGACCTGAAGGCTGCAAAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000135862:ENST00000258341:15
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=WD(100=94.2)
A:
NA
C2:
PF0005319=Laminin_EGF=WD(100=93.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAATTGCAATCTGTATGGGACC
R:
GTTTGCAGCCTTCAGGTCCAA
Band lengths:
294-863
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development