HsaINT0095568 @ hg38
Intron Retention
Gene
ENSG00000134013 | LOXL2
Description
lysyl oxidase like 2 [Source:HGNC Symbol;Acc:HGNC:6666]
Coordinates
chr8:23298836-23302163:-
Coord C1 exon
chr8:23302027-23302163
Coord A exon
chr8:23298948-23302026
Coord C2 exon
chr8:23298836-23298947
Length
3079 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
TCTGCCCTGCTTCTCCCTAGGTT
3' ss Score
11.66
Exon sequences
Seq C1 exon
ACATCCAGAAGAATTACGAGTGTGCCAACTTCGGCGATCAGGGCATCACCATGGGCTGCTGGGACATGTACCGCCATGACATCGACTGCCAGTGGGTTGACATCACTGACGTGCCCCCTGGAGACTACCTGTTCCAG
Seq A exon
GTGAGGTGGGTGGGAAGGGGTTCCAGCCCTGCAGGGGGAGGAGGGGAGGCCACCTCCACAGGCTCCTTCCCATTGGTGTCCACACAGGGGCATGGAAGTCAGGCTGTCTAAAGGGCAAGGTGCTACCCCCAGAGGCCATCACGGTCCATCAGTTAACCCAAAGATATCAGGCATGGGGGCCTGAGAAATAGGGCGTGCACAGGACCAGAGACACCACAGGCATTCACATTTGATTGAGTTAACACCTGGTGCATGCAAATCAAAACTCATCAGCAGGCTAGATTTGCTCCTCCGGCCAGTTTATTCCATACATGCTCAGGCAACCCACACCTCTTGTCTCCTATGGAGCTCTTGTCTCCACCATCCCCATTTCTCCTAGTGCCCTAGGCTGCCTTGGTCTGTGCTTTCAAGACTGAAAGCAAACTCATAAAGAGCCAGTCACTTGCAAATATCTGTGACTTAGCTCTTCCGGAAATATCTGCCTCATAGAGGAGGATCTGCAGAAGGGGCCATTCTCAATGCAAAGTGAATCTATAAGAATAAAATACTGAACACGAGACACAGCCTGGCCAGGTGACTTCTTTGTCAGAGGGGTTGCCGAGATTTGTTTCCACATACTCTGGGTGGAAGGCCAGCCCTGAGGAGGAACAAGGGGGCCTTGGCTTCCCTCCTTCCTGAAAACAGCGGCATGTTCTGGCCAGGGCTCTAACTGGGGGAGAAAAGGGGCATTGTGTCCCTAGTGTCTCTCCCAGTGCACGGGTACACGTAGCCTGCAGAAGCTTTATCTCACCCTCTCACTCTCTCCTACGTCCTCACCCATCTCGTTTTCCAGCTTGCCCTGTTGGCTAGCAAAGTGGATGACCAGAAATGTGTCATTCCACCTTGAAAGCTTTCCTGAGGGGGCATTCAGCCAGCCCAGGGCCTGGCCCACGGTCCCCACCTACAGACAGTCCTCTGAAGAAACAACACCTTCAGAGAAGTCACCACAGAGGGGCTTTCAGAGAATTCCTGGGCAGTTTCAGAGGCTGGAAAGCAGACAGCCAAGCACTTTTCCACCCACAAGCCCAGAACCACAGACTTGGAGAGGCCTAACCAGAGAGTTATTTATTTTAAAAGATGAATAGCCGTGGCCATGTGCACGTATACAGTGCCTGGTGGTTTCTGTTTGAGGTTTGCTATCATTTTGCTGGGTGAGTGTGTATCTCCCTGTATTCTGGCCAGTGCCATCCACTTAATAACTACTATCAATTGCCTAAGCCTGGGGAATGCATTGTTTGATTTAATCTCCCAAGGAAGGGGCATCATCATTACCCTCATTTCACGGCCACCCAACCCCAGACATATCAACTCTTTATTTTGTTTTCTCAACCCCTAAACAATACAATTAGCAAATGGACTCATTAGGGGCATGTTAATACCTCTGATTAATCAAAAAGAACATTCCCCTTAAGATAGACATGGAGCTTCTTTAGGTGCCACAAGCACCGGCCTGGGGACTCACGGGACACAAGAGGTGGTCTTCACTTCAGACATCAGTGGTGCTGTGAAGGACAGGAGGAGGGAGCTGGGCGAGGAGGAAGTGACCGTCCACGCAGAGGGACCTGTGCAGAGCTCAGAGGCAGGGGTGAAGGGGCCTCCTGGCTCCTGGTGGCCCCGCTTTATCCGCTTTCTCATCATTTCCTAGATTCACAGACATACAGAAACCTAAAGCCACTTCCCGCAGGCCCTCGTGAGATGTCGGTCTGCAGTAGATGAGTGGGGTGAAACAGTGGGGGACACACATTTCCAGCCCCGCCTCCACCCCACACGTAACACTGGCCCTCGTGTCCCCAACACGAGCCCTTGCTGCATCCAGCCGCCCTCACGGCTGCACTGTCGAGACGCCTGGGCGGCCAAGGAGCTGCCTAGGCCTGCACAGCTGGAGGCCTTGGCATGTGGAGCTGTGTTTGCCCCATGCCATGTGTGGGCCAGGAACGAGGGGGCAGCTAGAATGGTTGGGTGGAAAAGAAAAAACTCAAGCCGCCCCGGAGCAGGGCATGTACCTCCTTAGCTAAAGGCACAGGGCCCCAGCGGGACACAGCTGAGCCAGGTGCAGGCCCCCAGAACAGCCCCGCTGGGCCAGAGCAGAGGGCCGGCTGCCAGGCTGGCCTTGGCTTCCCACAGCACCTCTTTGGGCAAGCCCAGCGGCCTGCTAAAGGTTCGTGTCCAGGCCCTTCTGGGGCCCCAAATTTAGAGAATGTTCCTGAACGAGCAGCCTGTACCCGCCCCCCTGCTGTGGGTCGCAGCCCTTCCAAATGTGGCAGGACCCTCGAGGGAAGGCCTGTCATCTGTGTCCTCTGCCCCTCTGTTCACCACTGTTGTCTCTTCTCCCTCTCCCTCCCTTTCTCTTTTCTCCTCGGGTCCTCACCGTAAACCTCCCCTTTTCTGTTCCCTCACAGACACTCTCCCAGAATATGTCCTTCCTATTCCTGCTGTAGCTGGGGGGATGCGGATACAGGGGTGGGTGGAAGGATGGGGAGAGGGTGCAACTTCTCCAGCAGCCCCAGAGCCAGGCCCTCGGCCAGCAGAGCAGACAGGGACATGGATCCCCAAGTCCCACCTGTCACTTTACAGAGAGAGGAAGGGACATGTCCACAGTCACACGCCTGTGACGAGTGTCCCATCTCCAACGCCCAGGCAGCCCTCTTCCAGGTTCCCACACCGCCAGGTCCTCCCTGCACCCTTCTGCTTCTCTTCAGCATCTTCTTTTTGGGGCCTCCCCAGACCCCAACTTCTGCCTTCCCCAGAACTCCCAGGAGTGGGTGACCCCCTTCCGAAGGCCCACCCTGGGTAGAGGGGTGTGTGTTACACGGATATGGACAGAGGGCAGGGTTTCCCTCTTCCAGGCCATGCTTCCTCTGCTCCCTGACTCATCTCTTCCCCTCCCCAAGGACTTTGTTGAGACCCACAGACCCCCGTCTTGGGTCCCGGCACCTGCCACGCTCCCCTTCCCTGAGGTGCTGGTCTCTCAGAGCCCCAGGCCTGGGTGGAGGTGGCCGCAGAGGGAACAAGCAGCCTCCTCTGCCCTGCTTCTCCCTAG
Seq C2 exon
GTTGTTATTAACCCCAACTTCGAGGTTGCAGAATCCGATTACTCCAACAACATCATGAAATGCAGGAGCCGCTATGACGGCCACCGCATCTGGATGTACAACTGCCACATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134013:ENST00000389131:12
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0118612=Lysyl_oxidase=FE(22.1=100)
A:
NA
C2:
PF0118612=Lysyl_oxidase=FE(18.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development