HsaINT0095586 @ hg38
Intron Retention
Gene
ENSG00000115318 | LOXL3
Description
lysyl oxidase like 3 [Source:HGNC Symbol;Acc:HGNC:13869]
Coordinates
chr2:74536291-74536928:-
Coord C1 exon
chr2:74536709-74536928
Coord A exon
chr2:74536472-74536708
Coord C2 exon
chr2:74536291-74536471
Length
237 bp
Sequences
Splice sites
5' ss Seq
GAGGTGTGT
5' ss Score
6.14
3' ss Seq
GGCACTTCTCTCTTCTATAGGCC
3' ss Score
9.89
Exon sequences
Seq C1 exon
GCTGCTAGCCCAACGGCAGCAACACTCCTTTGGTCTGCATGGGGTGGCGTGCGTGGGCACGGAGGCCCACCTCTCCCTCTGTTCCCTGGAGTTCTATCGTGCCAATGACACCGCCAGGTGCCCTGGGGGGGGCCCTGCAGTGGTGAGCTGTGTGCCAGGCCCTGTCTACGCGGCATCCAGTGGCCAGAAGAAGCAACAACAGTCGAAGCCTCAGGGGGAG
Seq A exon
GTGTGTGAGACAGTGATTATGACCTTTCCCACCCCAGGTGGAGAACCCCTAGCCTGGCAACCCCAGACTAAGCACAGCCCTGACCTTTGAGGACAGAGAGGAGCCTTCCAGGGGGTGGGCCACAGACCTGATACCACCCACTCCCTTCCACCAAAGTCTCACTCATCTCCCAGGTCTGCTTAGCCCTCCGTGCAGATGTTGCCATTTGCCTCTGTTGGGCACTTCTCTCTTCTATAG
Seq C2 exon
GCCCGTGTCCGTCTAAAGGGCGGCGCCCACCCTGGAGAGGGCCGGGTAGAAGTCCTGAAGGCCAGCACATGGGGCACAGTCTGTGACCGCAAGTGGGACCTGCATGCAGCCAGCGTGGTGTGTCGGGAGCTGGGCTTCGGGAGTGCTCGAGAAGCTCTGAGTGGCGCTCGCATGGGGCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115318:ENST00000264094:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.174 A=NA C2=0.120
Domain overlap (PFAM):
C1:
PF0053013=SRCR=PD(50.5=68.9)
A:
NA
C2:
PF0053013=SRCR=PU(67.9=90.2),PF0118612=Lysyl_oxidase=PU(23.9=44.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCAACACTCCTTTGGTCTGC
R:
CCACTTGCGGTCACAGACTG
Band lengths:
299-536
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development