HsaINT0096447 @ hg38
Intron Retention
Gene
ENSG00000081479 | LRP2
Description
LDL receptor related protein 2 [Source:HGNC Symbol;Acc:HGNC:6694]
Coordinates
chr2:169145747-169146959:-
Coord C1 exon
chr2:169146739-169146959
Coord A exon
chr2:169145924-169146738
Coord C2 exon
chr2:169145747-169145923
Length
815 bp
Sequences
Splice sites
5' ss Seq
AAGGTTAGA
5' ss Score
6.12
3' ss Seq
TTTCCCCTGTGGGTAAGCAGCAA
3' ss Score
2.65
Exon sequences
Seq C1 exon
GCTTATGTTCTGGACTGACTGGGGAAAGGAACCTAAAATCGAGTCTGCCTGGATGAATGGAGAGGACCGCAACATCCTGGTTTTCGAGGACCTTGGTTGGCCAACTGGCCTTTCTATCGATTATTTGAACAATGACCGAATCTACTGGAGTGACTTCAAGGAGGACGTTATTGAAACCATAAAATATGATGGGACTGATAGGAGAGTCATTGCAAAGGAAG
Seq A exon
GTTAGAAATTAGTTAGAAAGTAATATATTAAATTAATAATTAACATATTTCTAATGTCTTTGCCTGTTTTCTCAAGAAGGAGCCCTGCTCTTAGGAAATGGCTTATATAGTTTTTTAGATACCACCCCTCCACCCCCACCAACTCCCACCTGCTGAATTAAATGCAGATGAGTTCATTAGCAATAATTAAATCCTTTTCGTCCTTTTTACACAACTTTAAAAAAAAATGCTTCTCAGCAGAAGATATTGAAATAACTGAGTTTCCTGTTAGGTTGCCCCAGTAGAGGTGGTTTCATGTGTACCAATGTTAATTCATGTCTAACCGCTTCTGGACACATTCATTTTCACTTTACTAGATTGCCCAGTATGCACAACTGTAAATATCTAGGAGATGAACATTTTTTGTTGTTGTTGTTCAGACTCTGCAGAATTGCAATGACCCAGCACATATCACATTTTTCCTATTTGGTCAGATAGATGTCTTATGTTCAAAAGAAAACATAAAATCTTGCCATTTAAATTGTTTTCCAAAAATGCAGTAAAATCAGTAACTTGAAAGTGAGCTAGGGCCCTGTGATTGGTGTCGGGTGGTATACATCAATGTGGTTTAATTTCTATCTTCTTGACCTCCTAATGCAGCACACTTTCACAGTCCCATGTAGCTAAAGTCAGCCTGAATATTCCCAGAGCTTCAAGGCATTGTATGAGGGAATAATTCAAGCAGAATGACATCAGATCTAGAAGTGGCGGTAGGGTGTAGTGGGTATTTTCTTTTCAATAACCTTCTGTTTTGTTTTTCCCCTGTGGGTAAGCAG
Seq C2 exon
CAATGAACCCTTACAGCCTGGACATCTTTGAAGACCAGTTATACTGGATATCTAAGGAAAAGGGAGAAGTATGGAAACAAAATAAATTTGGGCAAGGAAAGAAAGAGAAAACGCTGGTAGTGAACCCTTGGCTCACTCAAGTTCGAATCTTTCATCAACTCAGATACAATAAGTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000081479:ENST00000263816:69
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=56.0),PF0005812=Ldl_recept_b=PU(72.5=38.7)
A:
NA
C2:
PF0005812=Ldl_recept_b=PD(25.0=16.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGGACTGACTGGGGAAAGGA
R:
CGAACTTGAGTGAGCCAAGGG
Band lengths:
357-1172
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development