HsaINT0097554 @ hg38
Intron Retention
Gene
ENSG00000119681 | LTBP2
Description
latent transforming growth factor beta binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6715]
Coordinates
chr14:74506048-74506823:-
Coord C1 exon
chr14:74506698-74506823
Coord A exon
chr14:74506192-74506697
Coord C2 exon
chr14:74506048-74506191
Length
506 bp
Sequences
Splice sites
5' ss Seq
TGGGTGAGG
5' ss Score
6.74
3' ss Seq
CCTGTTCTCACACCTGGCAGATG
3' ss Score
8.84
Exon sequences
Seq C1 exon
ACATAGACGAGTGCGCCAACGACACCATGTGTGGCAGCCACGGCTTCTGTGACAACACTGATGGCTCCTTCCGCTGCCTCTGTGACCAGGGCTTCGAGATCTCTCCCTCAGGCTGGGACTGTGTGG
Seq A exon
GTGAGGAGCCTGTGGGCTACCCAAGGTCTGGGCCAGGGAAGGGAAGGCCCTGGGGTCCTCCTCCTCAACTGGTCCTGGTCACGTGGCTCCATCACGGGTCCCCAGAGCATGGGCAAGGGAGGCTTCAAAGAAGAGGGAGACTTCAACTCCTCGCCCAGGGGCACATGGGCCGGGCGGGTAAGGGGAAGCACAGCCGCGCTCTGCCAGCAGGGCAGCAGGTGTCCTCAAGCCTCAGAGCCTCAGGAGGCAGGAGGTTTGGAGAATGTGCACTGAGGGGTAACCCTTCCTCTTTGTGCACTTCTGTGACCGTTTGCTGCCACTCCTCTCCTTTTTTCTTCTTTCCCATGCCCTCTGTCCATTGGTTCCTCCTCCCTACAAATCTATACTTACTCTTGTTTCTTCCCCAAGGCCTAGCCTGCTTCTTTTGGGGGCAGTGGGCTGTAGTCAGGGGCAGGGGGCACGGGCTGCCTCTTTTCTGCCCACGAGCCTGTTCTCACACCTGGCAG
Seq C2 exon
ATGTGAACGAGTGTGAGCTTATGCTGGCGGTATGTGGGGCCGCGCTCTGTGAGAACGTGGAGGGCTCCTTCCTGTGCCTCTGTGCCAGTGACCTGGAGGAGTACGATGCCCAGGAGGGGCACTGCCGCCCACGGGGGGCTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119681:ENST00000261978:27
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.061
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=95.3),PF0764510=EGF_CA=PU(0.1=0.0)
A:
NA
C2:
PF0764510=EGF_CA=WD(100=85.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACATAGACGAGTGCGCCAAC
R:
CTCCTGGGCATCGTACTCCTC
Band lengths:
242-748
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development