HsaINT0097555 @ hg38
Intron Retention
Gene
ENSG00000119681 | LTBP2
Description
latent transforming growth factor beta binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6715]
Coordinates
chr14:74504983-74506191:-
Coord C1 exon
chr14:74506048-74506191
Coord A exon
chr14:74505175-74506047
Coord C2 exon
chr14:74504983-74505174
Length
873 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGG
5' ss Score
8.41
3' ss Seq
TGAGCATCTGTCACGCACAGGTC
3' ss Score
5.56
Exon sequences
Seq C1 exon
ATGTGAACGAGTGTGAGCTTATGCTGGCGGTATGTGGGGCCGCGCTCTGTGAGAACGTGGAGGGCTCCTTCCTGTGCCTCTGTGCCAGTGACCTGGAGGAGTACGATGCCCAGGAGGGGCACTGCCGCCCACGGGGGGCTGGAG
Seq A exon
GTGAGGCCTGGGAGACACATTATCCATGGTGACTCAGAGGTTTACAGAGAGCGTGTCCCTCTGCATCCCTCTACTAGCCTCTAGCCGCTGAGGGGGACACTGGGCCAGGGCCTGGGGCAGCATAGGGAGGTGCAGGCGGGGCCTGGTGCATGGAGGGGTGAGGAGGCTGAGGGCCGCGCGCAGCAAAACCAGGAGCTACAGGGTGGCGACGATCCTAGAGGAGGCTCAGGAAACCCTGATGCTGACTTAGGGTGGCCCCAGGGACCGCAGATTGAGCCTTGGAGGGACCCTGAATCCATCTAATCCCTGGGAACCTTCTGGATGAGAGAGGACTTGGAGCTGAACTAAACCGGGCTCTCCCTTTCCCACTTCCCACTCCACCCGAGAGCTCCTGGGTTCAGCCTCTCACGCCAGGCTGGACTAGGACTCAGCTGGTCTTCACTGCCTTGGGGGAAAGTGAGGGAGACGAGGAAGGGTGGGAGGGGCTGGGGTACATGTGAAGCAGAATGGACCAGAGGGCTGCCCATATGGCATGCCAGGCACTGGGGGCAGCCCGTCCCAGGGAGGCAGGCAGCATGGTATACCGCAAAGCGCAGGGGAGGAGGAACTGGGGTCAGATCCCTGCTGCACTGCTTAATAGCTTAATCGCACAGCAGTGGCGAGGCCCCAAGCCTCTCTAAGCCTCAATTTCTTGAGATGATGATTAGGCCACTTCTTAGGGTTGTGGAGAGCCTCAGTGAGGTAATACAGGTAACAGAATTTTTTCCACTGTAAAGTGCTACACAAATGTTAAATTTAAGAAATAAAGTCAAGGACTATTGACCCCCCTTAGAGGGTCATGAACAGACAGTAATGAGCATCTGTCACGCACAG
Seq C2 exon
GTCAGAGTATGTCTGAGGCCCCAACGGGGGACCATGCCCCGGCCCCCACCCGCATGGACTGCTACTCCGGGCAGAAGGGCCATGCGCCCTGCTCCAGTGTCCTGGGCCGGAACACCACACAGGCTGAATGCTGCTGCACCCAGGGCGCTAGCTGGGGAGATGCCTGTGACCTCTGCCCGTCTGAGGACTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119681:ENST00000261978:28
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.061 A=NA C2=0.123
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=85.7)
A:
NA
C2:
PF0068312=TB=PU(85.7=55.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGAACGAGTGTGAGCTTATGC
R:
CTCAGACGGGCAGAGGTCA
Band lengths:
327-1200
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development