HsaINT0097569 @ hg19
Intron Retention
Gene
ENSG00000119681 | LTBP2
Description
latent transforming growth factor beta binding protein 2 [Source:HGNC Symbol;Acc:6715]
Coordinates
chr14:74999129-75002703:-
Coord C1 exon
chr14:75002629-75002703
Coord A exon
chr14:74999252-75002628
Coord C2 exon
chr14:74999129-74999251
Length
3377 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGGA
5' ss Score
9.45
3' ss Seq
CATCTCCTCCAACCCTGCAGATA
3' ss Score
8.66
Exon sequences
Seq C1 exon
CCTCCCCGGTGATTGAGAATGGCCAGCTGGAGTGTCCTCAGGGGTACAAGAGACTGAACCTCACTCACTGCCAAG
Seq A exon
GTAGGACCCCCAGGGCCAGGGCTGGGCTCAAGGATGCCGGGGCACACTCCCAGCACCAGACAGGAGGGGTGTCTGTCACTGGCCGAGTGGTCTCCACTGAGTCCCTCTAAGCCCCAGCTTTGGGGAGTGGTGGGGGGCTGCTGATTCCAGGGGACTAAGGAAATCCAGGGACTTGCTTGAGAGTGACAGAGGAAGCCAAGGGGGCCGACACCTCCCCTCGTCCCCATCTCCACCCACACCCACCTGGAACACAGGCTAGGGGCTCTAGGCTATGTGGGGCTGTGTCTGAAGGGGCCACCCCAGTCTGTGCACTTCCACTTTTCTCCTGAGCTGGTCTCCCTGGAGTGGGAAGAATTTCAGCTCTAGGGTGGGAAATCAAGTCAGCCTGAGTTGTTGGGGCCTCTGTGGGCTTTTCCCAACTGAAAACCTTTAGCTACTCAGGCTTCCCTCCCGCTTGCTTCAACCCATAGCCAGGAAAGGGGACGGGGAGCACGGGGGCTTCCTGCCTGGGACAGGCTCCTGGGGCTGGCAGAGGCCAGTGGGGAACAAGGTGGCTTCCCTGTGGGGAGCTTTGACAACTGGACAAACAGTTGTCTGTATGGTTTGCTTTGGGTGGAGCTGGGTCAGAGACAGGGGATTGACCCAGATGGCCTCCAAGGTGCCCTCCTCCTGGAGGTTGCTTCAGAGAGAGGAGTCTGGGGAAGCTCTGCATGGCTGGGCTGTCTTCCTTGGGGGTGCCAGGCTGCAGAAGTGATTCCTAGCCCGTGGATAAGCAAAGGTGCTGGGGCCAAGCAAAAGGGCAGGTCTCTGGCCCAGCCTAGTCCAGAGTCAGACTCCCTCAGGAGCCAGTGGTTTGAGGGCCAAGCAGACAGTGGATGTAGGGAGAAATACGTATTTTTGCCTTTGGAGGGTACATCGGGGCTGTTCATGTCTAAACAGTCACCAGTTGCTTTTCCTCCTGGTATGTTTCCCAATCTGGAGCTTTAAGGTTATACTCAGGATCTCAAATGGGCTCTCTGCCCTCCCTCTACTGAGCCCCAAGATTCAGGACACCAAAGGACCTTCCCTCAGGAGGCCCTGCCCCTGAAACCTCCCCTTCCCATGTATGTGGCTGTGGTCTCTGTGTCTGCGAAGGGACCTGCTCATCTCTGCACCCGCATGCGTCATCTCTCCTCTCTCTCCATCCTTCTCTCCTACTTCCACAGAGTATTGGAGGGGAGGTTACTATGGGCTACATACACTGTGCTAGGAGTACACAGTGATGGAGAAGACAGTCCTGCCCCAAGTGCAGACAGACCCCCTGAACAATCAGGTCTAATGAGCGGGGCATTCTTGAGAGAAAGCAGCAGTCCCTGAGTGCTACAGGATCCCATGGTGGGGGCGCCTTCCCAGACTGGAAGGATCAGGGAAGGCTCCCTGGAAAAGGTGATACCTAAGGCCAAGACTTTAAAAATGAGTACACGTTGGCCAACTAAGAGGATGCAAGCTCTCCAGGCAATGTGAACCCCATAAGCAAAAGAACAGTTTGTGCTGTCTGGAGTGTCCCAGAAAGTACTGTGTACGTGGCCTGTGTACACACGGGAGATGCCACATGTCTGCCAGTGTCTCATCAGAGCCACCTGTTTACCCACAGGCTTTGGGGAAAGGTAGAGGGCCTTGGATACCATGTTAGGGTTTAGAGCCTCCCTCTAAGAAGTGACAGGGAACCCAGAAGCAGAGGGAAGCAAGTCAGATTTGGGTATGGAGGCCCACATCCCACTGTGGCCACAGTCTGGATGCATATGGATCACTGCCCCTTCCCATTTCTCAGTAGCACCTTCCCAGCTCTTATTGGCACCCTGCCACAATGGGGCATCCTACCAAGGAGTAGTGCCCCTTGGTGCTCAGGCTGGGTCACCTTTCAGTCCCTCGTTCCTGTGCCCAGTGCCAATTTCCCCAAACCGGTGGGTGACCTGGCTCTGCAGACACAGGGCTGCCTGTGTTACCGCCTGGCCTGGAGGCAGGTGCCCCTCACAAGCAATTAATGCTTATCATCTCTGCTGCCATCACCACCATCAATAGAAGTGCCATCATCAAGATGGCCCCCGACTCCTCATATCTTAGATTGTGAGGGCTGAGACTTCCCCTTGGCAGGGAGAAGTTTGCAGCAGGAAAAGGGGGTTTCCCCCTTTGAGGTCACAGAAGAAACCAGTGCACCTCCCTTATTTGAAGAACAGCATGAGCCTCCACGGGTTTCCGGGGGGATGCGTGCAGCCTGCACAAGGAAGGGCGTTCAGGAGGACCCGAAGATGTGCCCTTCTGACCCTCAACCTTTGCACACTCTTAACTGTGACCCCTGCTGTCCCCTTCCCCTTCAGTGCCTTCCTCCAGCCTCTGCCTCCTTTTCCTTACCAGGGTCCTCCCTCCTCCAGCTCACTGCAGACATGCTCCCAGGGTCTTGGGGCCTGCAGAGGTGCTTCAGGGACCTCTGGAGGAAGGCTGAATAGGAGGGACTTGGCTGCCCCTTCTCCACCTTCCAACCCACACAGTCCCCCTGATCTGTTTCCTGTCTGCATCTCAACATGCCACTCTCCAGCTGAATGACTCTGTGCCCAGTGCCAATTTCCCCAAACCAGTGGGTGACCTGGCTATTCCTGGGACCTCAGTTTCTTCTCCTGTAAAATGAGGACATGTGGGCCTATTTGATAAAATTGTTTGTGAGAATTAAATGGGGTATTATATGTTAATACCCAGCAGAGTACGTAGCATGTAATAGGTGCTCAATAAACACTAGCGCTTGAGGCCTGGCAAGGCAGCTCATGCTTGTAATCTCAGCACTTCGGGAGGCCAAGGCAGGCAGATTGCTTGAGGCCCAGAGTTTGAGACCAGCCATGGGCAACATGGTGAAAACACATCTCTACAAAAAATACAGTACAAAAATTAGCTGGATGTGGTGGTATGCACCTGTCGTTCCAGCTACTCGGGAGGCTGAGGCATGAGAATTGCTTGAACCTGGGAGGCGGAGACTGCAGTGAGCTGAGATCACACCCCTGCACTCCAGCCTGGGTGGCAAAACGAGACTCTGTCTCAAAAAATAGATAAATAAATAAATAAACATTAGCTCTTAATATTATGATCATTGTTACATGCCACTTATTGGACAAAGTGGTTTGCAATTTGATCTTATCCATTTAACAACACCATCTGGTTGTTACTATCATTATCCTCATTTTACAAATGAGGAAACTGAGGCACAGGGAGAGGAATCCCACTGAATACATAGCAGCTCTTTTGTTGTTGTTTTATCTGGAGAGAGTATTTGAAGATCTCTGCCCAGCCCCTCTGCTCCATCAGGCCTCCGTGGGGCGGGCACTTGGTCATCTCCTCCAACCCTGCAG
Seq C2 exon
ATATCAACGAGTGCTTGACCCTGGGCCTGTGCAAGGACGCGGAGTGTGTGAATACCAGGGGCAGCTACCTGTGCACATGCAGACCTGGCCTCATGCTGGATCCATCGCGGAGCCGCTGTGTGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119681-LTBP2:NM_000428:9
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0068312=TB=PD(5.1=7.7),PF0764510=EGF_CA=PU(0.1=0.0)
A:
NA
C2:
PF0764510=EGF_CA=WD(100=95.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)