HsaINT0103998 @ hg38
Intron Retention
Gene
ENSG00000087245 | MMP2
Description
matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:7166]
Coordinates
chr16:55491801-55493293:+
Coord C1 exon
chr16:55491801-55491956
Coord A exon
chr16:55491957-55493157
Coord C2 exon
chr16:55493158-55493293
Length
1201 bp
Sequences
Splice sites
5' ss Seq
ATGGTAAAC
5' ss Score
4.68
3' ss Seq
AGGTCAGGTGTTCTCCCCAGGGG
3' ss Score
5.43
Exon sequences
Seq C1 exon
GGTACAGCCTGTTCCTCGTGGCAGCCCACGAGTTTGGCCACGCCATGGGGCTGGAGCACTCCCAAGACCCTGGGGCCCTGATGGCACCCATTTACACCTACACCAAGAACTTCCGTCTGTCCCAGGATGACATCAAGGGCATTCAGGAGCTCTATG
Seq A exon
GTAAACCTCCGGGCGGGGGTTGGGGGTGGAGGGTGAGGAGGGGGGAGGTCATGTAGCCTGGGATGGAGGCCCAGGGGGTGGGACCAGCAAGATCTCATCCAGCCAGGAGTGCTGGAGACGAGGGCAGGAAATGGGAGTGTTGACCTGGTCTTGGGAAGGCAGAGCAGCTCTCCAAGGGGATACTTGGATAACTCTTCCCTATCCGAACAATGCTAATATCCATGTCACTCTTAGCGCTCCATTTCTGGGTTTCTCCCATTTTCTAGGTGAGTAAGGTCACCTGGTGCAAGGTTACACAGGTTTGAGCAACCCAGTGGAGTTTAGAATCCAGGAGAATAGCCAAGTACAGGACAGAATTTTCCATCATGTGGAATGACCTTAACAATACGGGGGTGGAAGTTTCTAGTTTTCATAATAAGCTTTGATTTTTAGTATGTAGTAGAAACAGAACAACCAGTGCCTTAAGCCAATTATTTATTTATTTATTTATTTATTTATTTATTTATTTATTTATTTATTGTTGGTTCTTACAGTGAGGCTAGAGTTTAAAAAGTCAGTTCATTTTTAAAAAATATTTAATGGTCCAGGTGATATCTGAGCCAGGCCAAAATAGTGAAAGTGGTGCTTGAGTGATGAAGTTTGGGGACTGCTAGACTCAGGAAAAAGCCCAAGGTCTGCCGTGAGGGGTGCTGGGTTCAAATGTGGCCTCTGCCCTTCACTAGCTGCAAGATATTGTGTAAGTCTTTATACCTCTTTGGACTCAGTTTCCTCATCTCTAAAATAATTGCTTATCATGAAAAGTGCCATACTGTCAGTTCTGGACACACCAGCGGCCCCCTGACCGCCCTGACTCTTGTGGGCATAAGAATCTGAGCTTTGGGTTTGAATCCTTGGGCAAGTCACTCAACTTTTCTGGGCCTCAGTTTCCTCACCTGTGAAATGGTGCAATCATGATACCCCACTCCCAGGGCTATAGAGAGGACTGATTTGGGTGATGTCAGTAAAAAGCATATATAAAGTACAAAGGGCCCCAGGACTCCCCAAGTCCAGGCATCTTCTTGTTACCTTACGGAGCTTACACTAAGGCCAGAAGGCGATTTCTTCTGACTCTTAGATGGTTGGGTGGGCACCCCTGGGGGCTCACCCTAGTGGGGAGAACCTCTGGAGCTGCAGAGAGTCTAAGGTCAGGTGTTCTCCCCAG
Seq C2 exon
GGGCCTCTCCTGACATTGACCTTGGCACCGGCCCCACCCCCACGCTGGGCCCTGTCACTCCTGAGATCTGCAAACAGGACATTGTATTTGATGGCATCGCTCAGATCCGTGGTGAGATCTTCTTCTTCAAGGACCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000087245:ENST00000219070:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.102
Domain overlap (PFAM):
C1:
PF0041319=Peptidase_M10=FE(15.8=100)
A:
NA
C2:
PF0041319=Peptidase_M10=PD(0.1=0.0),PF0004514=Hemopexin=PU(36.4=34.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTACAGCCTGTTCCTCGTG
R:
TTGAAGAAGAAGATCTCACCACGG
Band lengths:
286-1487
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development