HsaINT0104095 @ hg38
Intron Retention
Gene
ENSG00000100985 | MMP9
Description
matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176]
Coordinates
chr20:46012427-46013534:+
Coord C1 exon
chr20:46012427-46012582
Coord A exon
chr20:46012583-46013254
Coord C2 exon
chr20:46013255-46013534
Length
672 bp
Sequences
Splice sites
5' ss Seq
ATGGTGAGG
5' ss Score
7.61
3' ss Seq
CACCCCGTGTCTCTTTTTAGGTC
3' ss Score
12.91
Exon sequences
Seq C1 exon
GATACAGTTTGTTCCTCGTGGCGGCGCATGAGTTCGGCCACGCGCTGGGCTTAGATCATTCCTCAGTGCCGGAGGCGCTCATGTACCCTATGTACCGCTTCACTGAGGGGCCCCCCTTGCATAAGGACGACGTGAATGGCATCCGGCACCTCTATG
Seq A exon
GTGAGGCAGGGGCAGGGATGGGAGGAGGAGGGGAAAGGGCGTGGCTGTGCCACAGTACCAAAGAATTGGGGGTTGGGGATCGGGGGAGGAACGGGGCGTGCAGGAGAGGTGGGACCTCAACGTCTGTCTGGAAGCAGAGCCTGGGCCCAGTCGCTGCCATGTCAGTGCTTAGAGGTGGTGATAAAGAGACTCTAGAGAGAGATAGGTGTGACTTCAAAAGCCAGTCTACTCTGGGCATGGTGGCTCACGCCTCTAATCCCAGGGCTTTGGGAGACCCAAGGCGGGAGGATTGCTTAAGCCCAGGAGTTCCAGACCAGCCTCGGCAACATAGCCAGACTCCCATCTCTACAAAAAATAAATGAGCAAGGCGTGAAGGCACATGTCTGTAGTCCTAGCTACTCTGGAGGCTGAGGTGGGAGGATCTCTTGAGCCCAGGAGTTCGAGGCTGTAGTGAGCTATGATTGCACCACTGCATTCCATCCTGGGCCATAGAGGATGTCGCTTAAAACGAAAAAGAAGAAGAAGAAAGTCCTGTGGTTTGGGAAGGGAGGCTGAGTGAGGAGGGGCCTGTGTGCCAGAGGAGGCTTCACTGAGAAGCTTAGGGGAGCAGATGTTCTAGGGGTACAGAGGTATGCAGGAATAGGAAGAGTCTCACCCCGTGTCTCTTTTTAG
Seq C2 exon
GTCCTCGCCCTGAACCTGAGCCACGGCCTCCAACCACCACCACACCGCAGCCCACGGCTCCCCCGACGGTCTGCCCCACCGGACCCCCCACTGTCCACCCCTCAGAGCGCCCCACAGCTGGCCCCACAGGTCCCCCCTCAGCTGGCCCCACAGGTCCCCCCACTGCTGGCCCTTCTACGGCCACTACTGTGCCTTTGAGTCCGGTGGACGATGCCTGCAACGTGAACATCTTCGACGCCATCGCGGAGATTGGGAACCAGCTGTATTTGTTCAAGGATGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100985:ENST00000372330:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.264 A=NA C2=0.713
Domain overlap (PFAM):
C1:
PF0041319=Peptidase_M10=FE(15.8=100)
A:
NA
C2:
PF0041319=Peptidase_M10=PD(0.1=0.0),PF048867=PT=WD(100=38.3),PF0004514=Hemopexin=PU(35.6=17.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGATCATTCCTCAGTGCCGGA
R:
ATGGCGTCGAAGATGTTCACG
Band lengths:
345-1017
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development