HsaINT0114862 @ hg19
Intron Retention
Gene
ENSG00000134250 | NOTCH2
Description
notch 2 [Source:HGNC Symbol;Acc:7882]
Coordinates
chr1:120539620-120548211:-
Coord C1 exon
chr1:120547952-120548211
Coord A exon
chr1:120539956-120547951
Coord C2 exon
chr1:120539620-120539955
Length
7996 bp
Sequences
Splice sites
5' ss Seq
CAGGTAACT
5' ss Score
8.63
3' ss Seq
TTTTGTTATCCTTCCTTTAGGTA
3' ss Score
12.09
Exon sequences
Seq C1 exon
ATGTCCAGAAGGCTTCTTGGGGGAATATTGTCAACATCGAGACCCCTGTGAGAAGAACCGCTGCCAGAATGGTGGGACTTGTGTGGCCCAGGCCATGCTGGGGAAAGCCACGTGCCGATGTGCCTCAGGGTTTACAGGAGAGGACTGCCAGTACTCAACATCTCATCCATGCTTTGTGTCTCGACCCTGCCTGAATGGCGGCACATGCCATATGCTCAGCCGGGATACCTATGAGTGCACCTGTCAAGTCGGGTTTACAG
Seq A exon
GTAACTAATGAGACCAAAGCCAGTGGTTTCCTACCTTCAGCAGATACCTTTATTTAGCATCTTTTAGATCATGGTGTCTGGCTCTTAAATGTCCCCCAGCTCTGGTGCACATTTAACATTATGATAAGGAACTGGGATGTTCCAGACAACTATCCCTAACTTCCTTTTAAGAGTTTCAGGGGGCAGAGAAAGAGAAAGAAAAAGTACCAAATACTTTGACTGCTTAAAGTATATATGTCAGGGCCAGGTGCGGTGGTGCACGCTTGCAATCCCAGCACTTTGGCAGGCCAAGGCAGGAGGATCACTTGAGGCTAGAGGTTTGAGACCAGCCTGGGAAACACAGCAAGACCCCATCTCTACAAAAAAACAAGAATAAAAATAAAACAAAATTAGTCATGTGTGGTGGTGTGCACCTGTAGTCCTAACTACTTGGGAGGCTGAAGTGGAAGAATTGCTTGAGCCCAGGAGTTTGAGGCTGCAGTGAGCTATGATCGCACCACTGCATTCTAGCCTGGGTGACAGAGTGAGACCCTGTCTCAAAAAAAAAATATGTACACCAGGATGGGGAATCAGAGTTTACTTCACTAAAAGAAATAAGTACACTGTCACCAGAGGAAAAGTTGCTGAAGTTATTGACTATTTGCTTTTAGAAATCTCCCTCCCTAGACATTCAGGGCACTGGCTTTTCTGGTTTTCTGAACCCTGTTCCTTTTGCTTCTTCATTACCTTGTTCTTATCCATTAAATGTTTGTGCTCCCTGGAGCACTGTTTTTCGCCCTCTTTTGAGCCACATCACAGCTCTCCCTAGGGAATTTCACTGTCTGTATTCGCCTCCACTGCCACTGTCTTCATTAGCTTGCTGATGAATCTCACCATCATTCCCTTAGCTCCACCCAACCCTGACATTCAGGCTCATGTTTCTAGCTATCCTTTGTATGTTCTCCTTGGAGATATTCTACAGGTACTTTCAGCTCACCTTGTTGACAGAAATACGTAGCAACCATGTACATCCCAAATACCCACGCTAGAAACTCCCTGTCCCTTGTTCTGACCTCATTTCAACTCAGTCACCCAAGCCAACCTCTGAGTTGCCTTTCACCTGTCTATTCCTCCCATTTCCTCTGCTACCCTGTAGTTGAGGGCCATGTTATCTCTCACCTGGACTTCTGAAATAGTTTCTGAATACGTTTTCTTGCCTTTATTCTCTCCCCATCTCATTCACCCATGATATTACTACATCTTTGATTATAAATGCAAATATTCTAACAATCTCACCTGCTTACAATGTCTAATATTTTTTCATCATCCGCAGAATAAACTGCAAACTCTTTTACATGACTTCCATAGCTCTCTACAGCCTAGACTTTACATCTTTTTGTAGCCTGGCCTCCCCACAAGCATCTAGGCCTAGTCACACCAAATTCTCCTTATTTCCTGAAAATGTTGTACTTATTATTGCTTCCATACAGTTACACACCCTTTTGCCTGGAATGCCCTTTTCTACAACTGGTGATTGTCCAATGTTATTTAAAACTGTGTCTTAGTGACCCTTTCATGATTCCTTTAGGCAAATGGTCTCTAAGTTTTATTAGTTTTATGTATCACATTTTATTGTAATTTTTTTTTACACATATCTCACCTGAATAGATTGTGGGTTTTTCTAGGTGGGTCTGAGCTTTATTCAAAAGTGTTTATTAAATTAGATGAGAAAAGGAGGAACATTCTTCATTTTTTCTCCTGCTTTAAGCACTAAACCAAGAGTTCTATAAATGCAATAAGCAAAAAAGTGAAAAATGTACTCAGAAAACTATACTGGATCAGTTAGTGTAGAATACTGTTATATTAATTTTTCATTGTATTAGGGTTCTCTAGAGGGATGGAACTAATGGAATATATATGTATGTATATATATTCCAACCCAAAGTGTCTTGGTGGCAATCTTAATATATATATATTGGCAATCTTTATATATATATAAAGGAGAGTTTGTTAAGTATTAATTCACATGATCACAAGGTCCCACAATAGGCTGTCTGCAGGCTGAGGAGCAAGGAGAGCCAGTCTGAGTTCCAAAACCAAAGAACTTGGGGTTCGATATTTGAGGGCAGGAAACATCCAGCACGGGAAAAAGATGTAGGCTGGGAGGCTAGGCCAGTCTCGCTTTTTCATGTTTTTCTGCCTGCTTTATATTTACTGACAGATGATCAAATGGTGTCCATCCAGATTAAGGGTGGGTCTGCCTTCCCCAGCCCACTGACTCAAATGTTAATCTCCTTTGGCAACACCTTCACAGACACACCCAAGATCAATACTTTGTATCCTTCAATTCAATCAAGTTGACACACTCAGTTTTAACCACCACAAATCTACCCCTTGTCAACTTGAACCCATACACATCTCCTGAGATCACACATAATCTTCAAATAAAGACAATAATTAGGTCATAATTACACCTGATGTAGTACAACTATTCTTCATACATCCGGAAACACACCAGTCCCCAGCTGAAACACTCTTACATAAAGTTAACGATACTTAAATGCTGATGTGAAGTCAATAAATCTTATGTCACATGATAAAGGAGAAAGGAAATAAAATGAAGATATTTTCTTAGTACAAGTGTGTGCAAGCACAGACATGTTTTTAATAAAAGAAGGAGGAAATACTGAGGACAATTACAGTCCTCATTTCTGCAGCTGGTCACATGGTAGTAGCTGGTATTGATGACTACCTTCTTCTACCCATTTTGTATTCCTTTTGCCTTCAGCAAACACCTCAGCAGGTTATGTTTTTTTTTTTCCTGATGGAGAGGCCCAAACCTTCATTCATCCAGGTGGGACCATTTGTAGTTCCGCCTGGATTGGGCTGTTGTAGTTGCCCATTGACCTTAATCACAGGGCATGGTAATACTAAGAGACGCCCTAATGGATCTCCTGTATTCCATGAATACTCTTTCTTACCTCCGTTCTGGAGTAGTAGACTGATTTCATCTTGATAGCCTGGGTCTTGATAGCCTTGATGTCCCAGCCAACACTGTAACGCCTTTCTTACCCTGTTTACTTAAAGGTAGGAACCCAAAGTGTCCTGGTGGCAATCTTAACTACCAGTTTAATGGAATTGTTGTTGTGTCTTCTGGTGGCAGCATTCCTCCCTCTGGAACTAAGACCTCTAGGCCAGCAGAACTTAATGTTGCGGGAACAGGAAGCAAACATTTTGCTAGTGGATCACTAGGGGTGATGGTGAGTGGTACCACTTCCATTTCCACCCCTTGATTCCTGGACCTGTGAATCCTGGCTATGGGAGAAGCAGTACCACATATTGGACGCTGATTCAGAGCATACACAGCCTTCTTGAGAACTTTGCCCCAACCCTGCAAAGTATTCTCACCTAGTTGGCATTGTAATTGTGACTGCAAAAGGCCATTCCACCGTTCTGCTTCAGGATGTTGGGGAACATGGTAAGACCAGTGAATTCCATGAGCATGAGCCCACTGCTGCACTTCTTTAGCCATAAAGTGAATGCCTTGGTTAGAGGCAATGCTGTGTGGAATACCATGACAGTGGATAAGGCATTCCATGAGTCCGCGGATGGTAGTCTTGGCAGAACCATTGCATGCAGGATAGGCAAACCCATATCCAGAGTAAGTGTCTATTCCAGTAAGGACAAACATCTGCCCTTTTCACAATGGAAGAAGTCCAACATAATCAACCTGCCACCAAGTAGCTGGCTGATCACCCTGAGGAATAGTGCCATATCAAAGGTGCAGTGTTGGTTTCTGCTGCTGGCAAATTGGGCACTCTGTAGTGGCAGTAGCCAGGTCAGCTTTCCACCGGCCCATCTTGTTTTCTGCACTGGGAAGTTGGGGCATGAGCACAAATGTTAGGACCTGAAAGGTGGTGAACTCTGCCTGGGCAGGGCAAAGCCAGAGGAAACTCTGGTGGAGGTCCGTAGCAGTCCTGATGTGCAAATCGGTCATCCAACCTGGGTGTAGGGGCGAAAGACTAATTGAACCATCTAGTAGCTGGTTCCCTCCAAAGTTTCCCTCGGGATAGTTGGCACTCTGGCAAAAACCCCACTCTTGGTACCAATTTACTGTATTAGTCCATTTTCACGCTGCTGATAAAGATATCCCCGAGACCGGAAAGAAAAGAGGTTTAATTGGACTTACAGTTCCATATGGCTGGGGAGGCCTCCGAATTATGGTGGGAGGCAAAAGGCACTTCTTTCGTGGTGGTGGCAAGAGAAAATTAGGAAGAAGCAAAAGCAGAAACCCTGAGAAACCCATCAGATCTCATGAGACTTATTCACTATCATGAGAATAGCACAGGAAAGACTGGCCCCCATGATACAGTTACCCCACTGGGTCCCTCCCACAACACATGGGAATTCTGGGAGATACAATTCAAGTTGAGATTTGGGTGGGGACACTACCAAACCATATCATTCATCAAAAGGTGTTGGTGGGGTAGAGGGTAGTTAGGATGATCCATTATCTCCATCATGACGATGATGGTATTGATGATGTAAGTCACTGAAAATATTTGGTGTTATAAGAATAATTTCTTCCTGATTGTCAGTTTTGAGTTGTTTTGCTATTAGGAGGCAAAGTAGGGGGGCATATACCCACTTAAAATATTTTAATTCTGGCTAGTGGAAATGACAGTAATGCCTTCTTCATAATTAAAATGTCACTCTGAAATGGTCCCAAATTAAAACTTCTTCCTTTGTTGTTAAGAAGGATCTCTTCTTGGTGTGTTCTGCAAGATTCTGATCACCTTTTTTTTTTTTTTTTTTTTGAGATGGAGTATTGCTTTGTCGTCCAGGCTGGAGTGCAGGGCACAATCTCGGTTCACTGCAAGCTCCACCTCCCGGGTTCACGCCATTCTTCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCACCTACCGCCATGCCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGCTTTCACCTTGTTAGCCACAATGGTCTGGATCGCCTGACCTCATGATCCACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACACCCGGCCGATTCTGATCATCTTTTATACATATGCTATTTTTGTCTATCACTTTAGGAATCATCACAGATCAAAGTCATCCTTTTGGTTTTTGTGATAGCACTATACCTCAGTCAGCTTACTAGCTCATCTCCACTCAGAGATGAAGAAGCAGAGGCAGCAAGTTAGTGCCTATACATAATATATATGGAAACCAAATTCAGGGTTGATTCTTTCTTTCTTTCTCCCTTCCTTCCTTCCTTTCTCCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTCTCTCTTTCTCTCTTTCTCTCTCTTTCCCTCTCTCTTTCTGTCTGTCTTTCTTCTCACTCTGTTGCTTAGTACAGTGGCGCAGTCTCGGCTCACTGCAACCTCCACCTCTTGGGTTCGAGTGATTCTTGTGCCTCAGCCTCCCAGGTAGCTGGGATTACAGGCATGCGCCATAAAGCCCGGCTAATTTTTGTATTTTTAGAAAAGATGGCATTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTAACCACAAGTGATCTGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATCAGCCACCACTTCCGGCCCAGGGATCTTTCTGTTTCAGTTGTGGGCATCACTCTGAAAATCACACTTGCTAGAAGTGAGCATTTATATCTCTTCTCCACTGTAAATAAGTGCCTCTTAGTGACATGAGTGGAAAGACAAGAAGAATTGCAGTTCCTTCATTTTCTGTCTTAGCTCCCTGAGATGTATATGCTGTGCCTAAATTTGTGTTATAGTTTTCTCCTTTGATTTGACATTCCTTGATAGGCAGAGAGCACTTTTCTGTGCTCATATGTCACATCTCGCATCTTTTTCCCTTATAGAAAAACTCTTGTGTCTCCCATTTACCTTTCTATGAGGTCAGAGATTTAGATACTTTCCTAGACAATCAACTGGAGTATTAACAAATTCAAGGAGTTCTCGCCATCCCGTTACTGGATATATACCCAAAGAATTATAAATCGTGCTGCTATAAAGACACATGCACACGTATGTTTATTGCGGCACTATTCACAATAGCAAAGACTTGGAACCAACCCAAATGTCCATCAATGATAGACTGGATTAAGAAAATGTGGCACATATACACCATGGAATACTATTCAGCCATAAAAAAGGATGAGTTCATGTCCTTTGTAGGGACATGGATGAAGCTGGAAACCATCATTCTCAGCAAACTATTGCAAGGACAAAAAACCAAACACCGCATGTTCTCACTCATAGGTGGGAATTGAACAATGAGAACACTTGGACACAGGAAGGGGAACATCACAAACCGGGGCCTGTCGTGGGGTGGTGGGACGGGGGAGGGATAGCATTAGGAGATGTACCTAATGTAAATGACGAGTTAATGGGTGCAGCACACCAACATGGCACATATATACATATGTAACAAACCTGCATGTTGTGCACGTGTACCCTAGAACTTAAAGTATAATAATAATAATAATAATAAAAATTCAAGGAGTTCTCATCTCTGTAGTTTAAATAATAAGTGACTTAGACTAATGACAACAAAAAGCCAGCCATGTGAATACCAAATTTACTAGTTCTGTGAGGATATTTTTTTCTCTTTCTCTTTCTGCCTCAAAGAATCTGCTTTGCTTCCCCTGCCATCATGATTTAGTTTTCAACCCGTCAGAGTCTTCCTGCTAGTGCTGGTACTTTCCTACTTGAGAAAGTCCACGGAATACCTTCGAGACCTCTGTCCTCCTGATGGCTTCTATTTCATTTGTTATATAGGGACCCAGAGTTCCTTCATCATTTTCAAACACATCAACAGATATTTATAGCAAGGCCACAATTAATAAAATGTTTCCCAGAATATATGTGTGTGTTACATTTAGAGGAAACAGAAGTAGTATTGACTTGTTTCTATCACCAGAGGTCTATTTAGTAACTATATTTTGTGGAAAATATCGATATATTTTATCCATTCAACAGACATGATTTGAGAGCATACCATGGAGACCCAACCCTGCCAGTGTGGCAGGTGGTATAATAGAAGAAAATAGCAAACTTGGTGTATCTGTGTTTGCGCACATGTATGTATGTGAGGGGCACTAAGGATGACTTTACAGAGGTTGGAACTTTTGAGTACAGTTGCCAAGATAGGGAGAGTTCACTAGGAAAACAGAAGGGAAGTTGATTTTTTTTTTTTTTTTTTTGAAATAGAGTCTTGCTGTGTCGCCCAGGCTGGAGTGCAGTGGTACAATCTCGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTTCTGCCTCAGCCTTCCAAGTAGCTGGGATCACAGGTGCGCGCCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATATTGGCCGGGCTGGTCTTGAACTCCTTACCTCATGATCTGCCTGCCTCGGCCTCCCAAAGTGCTGGAATTACAGGTGTGAGCCACTGCTCCTGGCCCGGAAGTTGATATTCAAACAGGAGCAGCATATGCAAAGACAGTGAGCTCTGAGAGAGTAGATGGATCCAGACTCCTATTGCTGATAGCGTCCTGCAGGATTGGGCTTCAATGTGACTAACCTACAATTGCCTCCAGGTGCTCCACCCACTGAGTCCTTGTGTCTCTGCTGAGGTCCTTGGAGAGTTACTGGAGAGGGCTCTGTGTCAGATTACCTTGAGGAGGCTCTGATTTAGCCTTTTGTAAAATGCAAAGAGTTGAGGTCTTCTCCACGCAAGAGCTCGCTGATGTCAATGAGGTATTGAGGATGGGGCCATCTCCTATTTCTGTGGCCAGTACTGAGTTTTGTTATCCTTCCTTTAG
Seq C2 exon
GTAAGGAGTGCCAATGGACGGATGCCTGCCTGTCTCATCCCTGTGCAAATGGAAGTACCTGTACCACTGTGGCCAACCAGTTCTCCTGCAAATGCCTCACAGGCTTCACAGGGCAGAAATGTGAGACTGATGTCAATGAGTGTGACATTCCAGGACACTGCCAGCATGGTGGCACCTGCCTCAACCTGCCTGGTTCCTACCAGTGCCAGTGCCCTCAGGGCTTCACAGGCCAGTACTGTGACAGCCTGTATGTGCCCTGTGCACCCTCACCTTGTGTCAATGGAGGCACCTGTCGGCAGACTGGTGACTTCACTTTTGAGTGCAACTGCCTTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134250-NOTCH2:NM_024408:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF079748=EGF_2=PD(28.6=11.4),PF0000822=EGF=WD(100=37.5),PF0000822=EGF=PU(93.8=34.1)
A:
NA
C2:
PF0000822=EGF=PD(3.1=0.9),PF0000822=EGF=WD(100=27.4),PF0764510=EGF_CA=WD(100=35.4),PF0000822=EGF=PU(81.2=23.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)