HsaINT0120877 @ hg19

Intron Retention

Gene

ENSG00000105717 | PBX4

Description

pre-B-cell leukemia homeobox 4 [Source:HGNC Symbol;Acc:13403]

Coordinates

chr19:19680918-19681642:-

Coord C1 exon

chr19:19681395-19681642

Coord A exon

chr19:19681109-19681394

Coord C2 exon

chr19:19680918-19681108

Length

286 bp

Sequences

Splice sites

5' ss Seq

CAGGTGATC

5' ss Score

4.28

3' ss Seq

TGTCTGTGCTCCCACCCCAGGCC

3' ss Score

9.31

Exon sequences

Seq C1 exon

TGGTAAGCATCCGTGGCATTCAAGACGAAGATCCCCCTGACGCCCAGCTCCTGAGGCTGGATAACATGCTGCTGGCTGAGGGCGTGTGCAGGCCCGAGAAGAGAGGAAGAGGAGGAGCGGTGGCCAGGGCCGGCACAGCAACACCAGGTGGCTGTCCAAATGACAATAGCATTGAGCACTCTGACTACAGGGCCAAGCTGTCCCAGATCCGACAGATTTACCACTCTGAGCTAGAGAAATATGAACAG

Seq A exon

GTGATCTTTCTGCATGGAAGAGTTTCTGTCATGTGAATGCGCATTTGTCAAAGCGAAACACGGAACGCTAACCACCTTTCTTTCGTGGCGCAGAACAGGGAGTCCATGCAGTTGGTCGCTGCAGAGGTGGTCCATTGTTACTGAAAGCCCTTTCCATTTACTTAACAGTCACCCGCCGGTGTGTGAACTACAGGGGGTGGCAGGCGGCTGCTCCGCTGTGGAACCTGCTGCCCTGTGCCACCCTGCTGCCTAGTCACAGGCCGGCGTGTCTGTGCTCCCACCCCAG

Seq C2 exon

GCCTGTCGTGAGTTCACCACGCACGTCACCAACCTCCTCCAGGAGCAGAGCAGGATGAGGCCTGTCTCCCCTAAGGAGATTGAGCGCATGGTCGGCGCCATTCACGGCAAGTTCAGCGCCATCCAGATGCAGTTGAAGCAGAGCACCTGTGAGGCAGTGATGACCCTGCGTTCGCGGCTGCTCGATGCCAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000105717-PBX4:NM_025245:3

Average complexity

IR-S

Mappability confidence:

NA

Protein Impact

ORF disruption upon sequence inclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.398 A=NA C2=0.234

Domain overlap (PFAM):

C1:

PF037928=PBC=FE(41.4=100),PF0076914=ERM=PU(18.6=36.1),PF070286=DUF1319=PU(35.2=37.3),PF040917=Sec15=PU(34.1=33.7),PF0044324=UCH=PU(25.0=73.5)

A:

NA

C2:

PF037928=PBC=PD(30.8=95.3),PF0076914=ERM=FE(39.1=100),PF070286=DUF1319=PD(62.5=85.9),PF040917=Sec15=PD(63.4=81.2),PF0044324=UCH=FE(25.8=100),PF0004624=Homeobox=PU(0.1=0.0)

Main Inclusion Isoform:

NA

Main Skipping Isoform:

ENSP00000251203f2406A