HsaINT0121960 @ hg38
Intron Retention
Gene
ENSG00000186642 | PDE2A
Description
phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]
Coordinates
chr11:72578897-72579383:-
Coord C1 exon
chr11:72579284-72579383
Coord A exon
chr11:72579010-72579283
Coord C2 exon
chr11:72578897-72579009
Length
274 bp
Sequences
Splice sites
5' ss Seq
AGGGTGACT
5' ss Score
2.76
3' ss Seq
CCCCATCCTCCCCTCAACAGTGG
3' ss Score
8.32
Exon sequences
Seq C1 exon
GACTATCAGCGCATGCTGGATCTGATGCGGGACATCATCTTGGCCACAGACCTGGCCCACCATCTCCGCATCTTCAAGGACCTCCAGAAGATGGCTGAGG
Seq A exon
GTGACTGCTGTTAGCCCCAGTCCTTGGGGCTGGGGAGGAACAACCAGGGGAAGGATTTGCCAGGGGAGCATTCCCAGGGTGCAGACCCATCCCCTGCAACATCAACCCTTCTCTGGCTGCACGGCCCCCCCCAGGCAGACCCAGCACTGGCCCCTTGGCTCCCATCAAGGGTGCCCAATTCCCTGGACCGCTCTGGGTTGGGCCCTGGGAGCCTTGTCCTCAGAAGGGCAAAGAGGCTGGGCCCCGCTCCTTGACCCCATCCTCCCCTCAACAG
Seq C2 exon
TGGGCTACGACCGAAACAACAAGCAGCACCACAGACTTCTCCTCTGCCTCCTCATGACCTCCTGTGACCTCTCTGACCAGACCAAGGGCTGGAAGACTACGAGAAAGATCGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186642:ENST00000334456:27
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=FE(13.9=100)
A:
NA
C2:
PF0023314=PDEase_I=FE(15.5=100)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGCATGCTGGATCTGATGCG
R:
CGCGATCTTTCTCGTAGTCTTCC
Band lengths:
204-478
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development