HsaINT0122509 @ hg19
Intron Retention
Gene
ENSG00000152256 | PDK1
Description
pyruvate dehydrogenase kinase, isozyme 1 [Source:HGNC Symbol;Acc:8809]
Coordinates
chr2:173423436-173427019:+
Coord C1 exon
chr2:173423436-173423577
Coord A exon
chr2:173423578-173426947
Coord C2 exon
chr2:173426948-173427019
Length
3370 bp
Sequences
Splice sites
5' ss Seq
CTGGTAAGA
5' ss Score
9.45
3' ss Seq
CCTATTGATCTGCATTTTAGGTA
3' ss Score
8.5
Exon sequences
Seq C1 exon
GATCAGTGAATGCTTGTGAAAAGACCTCATTTATGTTTCTGCGGCAAGAGTTGCCTGTCAGACTGGCAAATATAATGAAAGAAATAAGTCTCCTTCCAGATAATCTTCTCAGGACACCATCCGTTCAATTGGTACAAAGCTG
Seq A exon
GTAAGATTCTCATCTTGTGTTTGCAATTTGATGGAGTTGTGGACTTTATTCAAGGTTACAGCAAATGCTTTTTTTTACTCTTTGGTGGAATCTTTTTTGTTTTGTTTTGTTTTGTTTGAGACGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCGATCTTGCCTCACTGCAAGCTCCGCCTCCCGGGTTCAGGCGATTCTCCTGCCTCAGCCTCCCGAGTAACTGGGATTACAGGCACGTGCCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGATGATCTCGGTCTCCTGAACTCGTGATCCACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGACGTGAGCCACCGTGCCCGACCAGAGTCTTAAGGTAGTAGCAGTATTCTTTTTTTGGCTGGGGGCAGGTGGGGGCAATGTATTTGGGCTTGTGCCCTGAATCGTGGACTCCACAACTTCTTGATTTTGAGAAAGCCAGTCAAAACTGCACTGAAATACAGATGCTAAATTTAGGATTTATGTTAGTATATCTTCAAGGATATTATAAGAAAAAATGTCTGCAATTTGTTGATGACTGGGTATTTATGTATATTGCCTTTAATCCCTTCAACAACCTTGCACAGTGGGTATGATTCTCTCCATTTTATTCATTGTTATTATTTTTATTTACTTTTTGTTTTTGAAATGGAATCTTGCTCTGTTGCCCAGGCTGGAGTGCAATGGCATGATCTTGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCAGAGTAGCTGGGATTACAGGCACCTGCCACCATGCCTGGCTAATTTTTGTATTTTTAGTAGAAATAGAGGTTTCACCATGTTGGCCAGGCTGGTCTCAAGCTCCTGACCTCAGGTGATCCTCCCACCTTGGCTTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACTCCTGGCCTACTTATTTTTTTGAGACAGGTTCTTACTCTGTCACCCAGGTTGGAGTGCAGTGGTGATCACAGCTCAGCTCACTGCAACCTCCACCTCCCTGGCTCAGGTGATCCTCCCACCTCGGCCTCCTGAGTAGCTGGGACCACAAGTGCATGCCACACCCAGCTAATTTTTGTATTTTTTAGCAGAGATGGGGTTTTTCCATGTTGCCTACGCTGGCCTCAAACTCCGGAGGTCAAGGTATTTGCCCACCTGGGCCTCTCAAAGTGCAGGGATTATGGGCATGAGCCATTGTGTCTAGCCTGTTTATTATTTTTTAAATTAATTTATTTTCTTTTTAGAGACAGGGTCTCCATCACCCAGGCTAGAGTGCAGTAGTGTGATCATGGCTCACTGCAGTCTTGACCTCCTGGGGTCAAGAGATTCTCCTGCTAAGGCAGCTGCCTCCCGAGCAGCTGGGACCACAGCCATGCGCCACCATACCTGACCAATTCTTTTATTTTTTTGTAGAGATGGGGGTCTCACTTTTTTGCCCAGGCAGGTTGTGAACTCCTGGGCTCAAGCAGTCCTCTCACCTTGGCTTCACAAAGTGTTGGTATTACAGACATGAGCCACCGCACCTGGCAGGTTAACTCTGTACAGATGAGGATGCTGAGGCACATAAAGGTTAAATCTTTTGCGTAAGACAGTACCATTGATAGTGGAGTTGGGATTCAAACCCCCATTTGTCCATCTCTGCTATACCGTGCTATAGTCAGAATGATGAAATATATGAAAGGATATATGTATTTTTAATAAACTGTGTTTATTGAAGGGTATCTTTTTATAAATTACAAAAGTTAAAATGTTTATTTTTCTGTTTTAAAACAATTAGAAGTTTTTGGAATTGTGTAGAAAAAGTGTGATCTCTTCCCAAAGATAAGTAGAGATGTTAAGGGTATACACTCATGGAGCCACCTATATACAGCCTTCATTAATGTTACTGATTTAAAAGTGTTGTTCTTTTAAGCACTGTATGCTTCAAACAAATGAGTTGCCCAGAGTTAAGTCTTAAATGGAAAAGGTTTAGCTGCAGGGCATTTCCCAGTTATGATTCATGGAGATTCAAGTTTTCTTTTTGTAAGCATTATAGCGTATGGGAGAAGTTGATCTAATCGCAATTTAAAAAAGCAAAATATGACTGCTATATATATGATAATCAGATGCTATCTAGTCCAAGTATGGAATAGTTATAAGTGTGGATTAAATGGGAAGCATTTGTTTAGTAATTATGATGGGATATAATGGAGAAAATATAATATTCCATGGAAGATTTTTCCTGTTTTTAAAAAATTCTTCATTAGAAGTAGAATATGCTGCTTTTTGAAGCTTATCAGTCATGAGGTCTGATCGGTGCCTGTTGTAGGTACTCAAATATCTCTTGGATGGAGAGCGTAGTTGTTCTTGCCAATTAAGAGGAAATTAAGGGTTAAAGCAAAGCAGCAGCTGCTATCAGAATCCCTTAACTTTGGAATGCAGTAAGACATATTGCTTGTCAGAAACAGCTTTCCAAACCAACAGATGGAATTACAGGTTTTTAAAGCACTTCCATTGCTCCTAGATGCCTGCTAAGTTAGGACAGTTGCAGATAAAGTGCTTACAGCCAAGTGGAGCAGATCCCTTACACTGTCGAAGAAAGTAATTCAGTGGTAGCAAGTTATTTTTAGCTCTGGCCCCGCAGTGCCATTGTACTTGCCTGCAAGACCATCAGAAAATCATTTGGCCTTCTCTATTTTGCTCATTCCTTAACAGATGCTTTGATACTTCGAATTGTTAGATAAATTTAAAATGTACATTTTTATGACTTTTGTGTTTTTTGTTCAGTTTAAAAGAACCATGTAGATTATAGGCTTTCAATAAATACTTGTTAGTTGGACATAAATATGTAAAATTAAGGTTTTAAAGCACAGATATTTAAGATACAGTCTTAGAGCAAGAGAGGCTGTCCTCCTTTTACTGATAATAAGACAAATTAAGTCATTTGCCCAAGATCACATAGTTACTGGTGACAGATCTCAGCATAATCAGTATATATACTGTAATGTACAGTGGTAAATTAAAAAAAAATTAAAAGCCATTTTAGAATGTAGAACTCGGAAAATCTTAAAATTCTTAAATTTGACCTTTGCTTTTAGGAGAAAATGTGCACCTTCTACCATTCATTCCCAGCACTTTGCTTGAATGTGCATGGGTGTAAAAATTATACTTCAACCATAATTTATAGCAGTATTCTAAATTAAAAATTATAAAATGCTAAAAATAGCTTTTGAGCTAATTTTCATGATATTGAACTTTCAGAATATAAAAGAACAAACTTATCCTATTGATCTGCATTTTAG
Seq C2 exon
GTATATCCAGAGTCTTCAGGAGCTTCTTGATTTTAAGGACAAAAGTGCTGAGGATGCTAAAGCTATTTATGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000152256-PDK1:NM_002610:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF104364=BCDHK_Adom3=FE(78.3=100),PF104364=BCDHK_Adom3=PU(2.3=4.2)
A:
NA
C2:
PF104364=BCDHK_Adom3=FE(14.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)