HsaINT0126146 @ hg19
Intron Retention
Gene
ENSG00000065243 | PKN2
Description
protein kinase N2 [Source:HGNC Symbol;Acc:9406]
Coordinates
chr1:89289993-89294306:+
Coord C1 exon
chr1:89289993-89290069
Coord A exon
chr1:89290070-89294163
Coord C2 exon
chr1:89294164-89294306
Length
4094 bp
Sequences
Splice sites
5' ss Seq
AAGGTAATC
5' ss Score
7.46
3' ss Seq
TTACATTTTATCTTTTCCAGGAA
3' ss Score
10.93
Exon sequences
Seq C1 exon
AGATTTGAAATTGGATAACTTATTGCTAGATACAGAGGGCTTTGTGAAAATTGCTGATTTTGGTCTTTGCAAAGAAG
Seq A exon
GTAATCGAATGTTTTTAAGTTTCTTTTCTGATTCAGAATTACTGTTTCTTTGTGCATCAGTAGTTTTCAAGTTTGTCTATGGAAAACAAACTGTACTTTTAACTTTATTCTTCATTAAGACATTGTAGATACAATGAAAACATTGCTTATATAACCTAATTATCACATTAAGAATTTGTTCTCTGAATACAAATAAGGTTAGATGTATAGAAATCATAGTAAGCTTCTCTGTGTGATTAATAATTTTGTCACTACTTTAAGGAAGTATTGATTAAGCACCAAAATCGTTTATTCTGGTGAGACTGTACACAGTGAATTTCATAGGCCTGATAATTTCCTTCCAGCTTCTTAAAGTTGAAACATTTAAAAATAGAAAATAAATAGAGATAGGTATCTCATGTATGTTTTTTGTATATTCAAAAGTAAATAAGTAAATTGGGGAAATTTGAATCAGAGGTAACATAAGAAAGGATAAAGATCATGGGCTTAGGCACTAAACAGTTCTAGGTTTGAATCGTGGCTTTGCCACTATTTGCTGTTTGTCTTTGGAAAACTTAGTTTTAACCTCTTTGAGTCTTATTTCCCCAATTATAAAAAAATGGACATAGTTCTTTCTGTTTACTAGTTACTAACATTCTCTATCTCCCTCTGCACTGGTGGCTTCTGTTTGCTATTTAGCTTTGTTTCCATAGTGCATAACACAGTGCATGGTACATCTTAAGTATTCAGTAAGTGTTTGATTAATAAGTAGTTGGATGAATAAATGAATGAACTCTGTAGATATATGCCCATCACATACCCACTGACCTAATTGCTGAATCAAGTAAGTTTTTTCTTGACTGGGCTTCTTTTTATTGGACACTGTTCCTCTAAATGCTTTTGTTTCTCAGCATCTCTCCTTAGCCGGCTGCTCTTCACTGCAATTTTTTGACTAGCAGCTATATCCTAATGACTCCCAAATCTATTATTTCCTTTCCTATGGATTCCAAAGATATATATTCAACTGTCTACTAGACAGCTCTGCCTGAATAGTGAAGAGACACCTCAAACACTACCCAAACAAAAATCATTTATTTTCCGCCGGTAGTCTGGGTGTTGGTATCACAATCCCCTCAGCCTTCAATCTGAAAGTAAGGAATTATCTTGCGTTCTATCCTGTTCTCTACTTCCCGTATGTAGTTATTCACAAAATTCTACTGCCACTTAACCTCCTGAATATTTCTGAAATCTATCATTTCCAGTCAGCTCCTTTCACCCATTATCTTGTTTTGACAAGACAGGTATAATAATCTCCTAATTGTTCCTATTTCTAGTCTTTTTCTATCCCAAATCAACCTGCCATGTAATTGCTGAATTGCTTAAGGAGTCCATATAAATACAGATCGGACCATGGCACATACCTGCTGAAAACTCTTCAGTGGCTAGGATAAGGTGACATACAGTGCCGTTACTGATCTGCCTGCCTTCCTCTCTGGCCACATCTCTTGCTGCTCTCTGTTTAGTACTTTTTGCTGCAGCAACAATGAACTGCTTATAGTCTGTGTCCCTCTAGCACTGTCACCCATCCCAACTCTATTTGCTGACTAACATCTGCTCATCCTTGTCATTCAACTCAAGTGTAACCTCTACAGGCAAGTTACCAGAGATTCCCTTTTACTACCCCAACTCCCAAGTCTGCTTTAGGAGCCCTTCTTCACTATTCTACCTTATCTTGCTCTTCCCTTGTTGTTATAAAATTATCAATAAATATCCATTTCCCTCCAGTCTCCTGTAAGCCCCTTAAAGACTGTGTCTTACTCTCGTTTTTATGTTCCCGCTACTTGACACAGGTGCCTAGAACATAAAAGGTGCAGAAAATATGTGTGTTGAATAACCAGACTTATTAATGCATTATCATAAAAACATGTTTAGTAGATTATATAGCTAACAACTTTTGAGTGCTTACCGTGTGCCAAGAATTTTGCTTCATATGCATATCTCCTGTAATTTATAACAATCGTATGAAGGTAGATAGTTTTTTTGGAGGAAATATTTTATTTTTTATTTTATTTTTATTTATATAAATTTATAGGGTAGAAGTGCAATTTTGTTACATGCATAAATTGCATAGTGGTGAAATCAAGGCTTTTAGGATATTCGTCACCCAAATAACATACATTGTACCTATTAAGTAATTTCTCATCATCCACCCCCCTTCCACCTCCTCACCCTTCTGAGTCTTCCTTGTCTTATCATTCCACACTGGTAGATGGTATTATTAACTCTCATATACAGATGAAGAAACCTAGAATTTGATGTTAGACAACTTTCCCAACCTCCCACAGTTAACAAATGACAGAACTGGAACTTAAACCAGGTATTTATTAATCTAGAGCCTGATATTAACCACTTCCATGGAGTTTTACCAGTCTACAAGAAACATAAGTTATATTTCTTCATTAATTAACTTTTTCCTAGTTTTCTCCAAGTTACTAAAAGGCTGGTGCAGAACTTACATAGATATTAATACTATATCACTGTTTTTTTAAATAATATTTTATTGAAGAAAATAAAAATCATTATGATAGTGTTAAAGAAATTTTGCCAAAAAAAAATTTCTCCACTCCAGTGTGCTAATGTATCTAATTGTGCCCTTCAGGTCTTGGTTCATAGACACACATTCATTTCTATTTTATAGTCACTATATATGCATACCTAATTATTCTTAATTTAGGATTGAGAGCTTTTCTTTAAAATTCTTAAAAAGATGACACTTATGACAAGTTTTTAACACTTTGGAATACATAGAGATAATATCTTCAATATGTAGACTATATATTTGATTAACATATTAATAAATTATGAGGAACATATATTTAAAAACTAGTTAGCCAAAATGTTAATACAGGCTGAGTATCCCTTATCCAAAATGCTTAGAATGAGAAATGTTTTGAATTTCAGATTTATTTGGATTTTGGAATATTTGCATATATAAATAATGACATATCTTGAGGCCAAGACCCAAGTCTAAACACAAAATTTATATATGTTTCATATATACCTTATACATAGCCTGAAGGTAAATTTATATAATATTTTTAATAATTTTGTGCATGAAACTAATCTTAAGTACTTGCGGAATTCTCTATGGCATCATGTTGGTGCCCAAAAAGTTTCAGATTTTGAAGCATTTTAGATTTTGGATTTTTGGATTAGGGATGTTCAACCTGTACTCTCCCTTCCCTCCCCTTCCCTTCCCTTCCCTTCCCTTCCCTCCCCTCTTCTCCCCTCCCCTCCCGTCCCCTCCTCTCTCTCTCTCTATATATAATATATATTGAGATATATATATGTTTTTTGTTTGTTTGTTTTTTGAGACAGAGTTTTGCTCTTGTCACCCAGGCTGGAGTGCAATGACACAATCTCAGCTCACTGCAGCCTCCGTCTCCCAAGTTCAAGCAGTTCTCCTGCCTCAACCTCCCGAGTAGCTGAGATTACAGGCGGGAGCCACCATGCCCGGCTAATTTTTGTTTTTGTTTTTTTTGTAGAGACGGGTTTCATCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCACCCGCCTCGGCCTCCCAAAGTGCCGTGATTACAAGCATGAGCCACTGCACACGGCCCTATCTCTCTGTATTATATGACACATTTGGTCAGCTTCTGATTATCCAAGGGTTTGCTTTTTGGTATTTTTGAAACTTATTTTTTTTAGAATGTTGATTTTATAATGAAGTAAATAAACTTATTTAAGATTGAATTGGAAAGATAATGGAACTTCACAATCAGTTCATTTTGTTATAATTTCTTAGCTCCCTTGTAATGACAAGAAGAAAAAGTAACTGAAAAGAAACATGGATATCTTATTTCTATTTACCCATTAATTAGACAGTATAGTTGCTATTGCAGTTTTTGCTATACCAGTCCTTACTGTTTTCTTGAAATGTCTTAGATATGTCTGAATTTGTTCACCATGCACAAATGTGCAACTTTAATTTTGCCTCCCAAAGATAGCTTTGATTTTTTTTTTATGCTAGATTTGTTTTCTTTGCTAACAAATGTTTACATTTTATCTTTTCCAG
Seq C2 exon
GAATGGGATATGGAGATAGAACAAGCACATTTTGTGGCACTCCTGAATTTCTTGCCCCAGAAGTATTAACAGAAACTTCTTATACAAGGGCTGTAGATTGGTGGGGCCTTGGCGTGCTTATATATGAAATGCTTGTTGGTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000065243-PKN2:NM_006256:18
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(10.0=100)
A:
NA
C2:
PF0006920=Pkinase=FE(18.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)